Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   M28_RS05820 Genome accession   NC_007296
Coordinates   1138016..1138978 (-) Length   320 a.a.
NCBI ID   WP_002995771.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS6180     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1133016..1143978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M28_RS05805 (M28_Spy1128) - 1133853..1134560 (-) 708 WP_011284934.1 O-methyltransferase -
  M28_RS05810 (M28_Spy1129) - 1134626..1135822 (-) 1197 WP_002995765.1 L-lactate MFS transporter -
  M28_RS05815 (M28_Spy1130) pepF 1136198..1138003 (-) 1806 WP_011284935.1 oligoendopeptidase F Regulator
  M28_RS05820 (M28_Spy1131) coiA 1138016..1138978 (-) 963 WP_002995771.1 competence protein CoiA Machinery gene
  M28_RS05825 (M28_Spy1132) - 1139273..1139989 (-) 717 WP_002989197.1 pseudouridine synthase -
  M28_RS05830 (M28_Spy1133) nagB 1140108..1140812 (-) 705 WP_021340997.1 glucosamine-6-phosphate deaminase -
  M28_RS05835 (M28_Spy1134) queA 1141014..1142042 (+) 1029 WP_011284937.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  M28_RS05840 (M28_Spy1135) - 1142049..1143269 (+) 1221 WP_002989189.1 DUF3114 domain-containing protein -
  M28_RS05845 (M28_Spy1136) - 1143383..1143973 (-) 591 WP_002989185.1 serine hydrolase -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37748.20 Da        Isoelectric Point: 10.2013

>NTDB_id=24708 M28_RS05820 WP_002995771.1 1138016..1138978(-) (coiA) [Streptococcus pyogenes MGAS6180]
MTKILTALDGKNQLISLVTQPISTKPPFCCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=24708 M28_RS05820 WP_002995771.1 1138016..1138978(-) (coiA) [Streptococcus pyogenes MGAS6180]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTTGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTGGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTATCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTATAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.903

96.875

0.416
  coiA Streptococcus pneumoniae Rx1

41.613

96.875

0.403
  coiA Streptococcus pneumoniae D39

41.613

96.875

0.403
  coiA Streptococcus pneumoniae R6

41.613

96.875

0.403
  coiA Streptococcus pneumoniae TIGR4

41.613

96.875

0.403
  coiA Lactococcus lactis subsp. cremoris KW2

39.329

100

0.403

Multiple sequence alignment