Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvB   Type   Machinery gene
Locus tag   NTHI_RS02050 Genome accession   NC_007146
Coordinates   412606..413613 (-) Length   335 a.a.
NCBI ID   WP_005649027.1    Uniprot ID   Q4QNM6
Organism   Haemophilus influenzae 86-028NP     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 407606..418613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHI_RS02025 (NTHI0425) - 407638..408528 (-) 891 WP_005649010.1 replication initiation protein -
  NTHI_RS02030 (NTHI0426) proC 409189..410004 (+) 816 WP_011271979.1 pyrroline-5-carboxylate reductase -
  NTHI_RS02035 (NTHI0427) - 410004..411170 (+) 1167 WP_011271980.1 3-phenylpropionate MFS transporter -
  NTHI_RS02040 (NTHI0428) xerD 411201..412094 (+) 894 WP_011271981.1 site-specific tyrosine recombinase XerD -
  NTHI_RS02045 (NTHI0429) - 412267..412554 (+) 288 WP_011271982.1 DUF5339 domain-containing protein -
  NTHI_RS02050 (NTHI0430) ruvB 412606..413613 (-) 1008 WP_005649027.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  NTHI_RS02055 (NTHI0431) ruvA 413621..414235 (-) 615 WP_011271983.1 Holliday junction branch migration protein RuvA Machinery gene
  NTHI_RS02060 (NTHI0432) ruvC 414298..414870 (-) 573 WP_011271984.1 crossover junction endodeoxyribonuclease RuvC -
  NTHI_RS02065 (NTHI0433) - 414917..415657 (-) 741 WP_005649034.1 YebC/PmpR family DNA-binding transcriptional regulator -
  NTHI_RS02070 (NTHI0434) nudB 415669..416142 (-) 474 WP_011271985.1 dihydroneopterin triphosphate diphosphatase -
  NTHI_RS02075 (NTHI0435) aspS 416164..417930 (-) 1767 WP_011271986.1 aspartate--tRNA ligase -

Sequence

Protein


Download         Length: 335 a.a.        Molecular weight: 37076.41 Da        Isoelectric Point: 4.7793

>NTDB_id=24607 NTHI_RS02050 WP_005649027.1 412606..413613(-) (ruvB) [Haemophilus influenzae 86-028NP]
MIEADRIISGQAKVDEDVIDRAIRPKLLADYVGQPQVREQMDIFIKAAKLRQDALDHLLIFGPPGLGKTTLANIVANEMG
VNIRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYSVEDLTSIVARSADCLNLELEQQAAFEVARRSRGTPRIANRLLRRVRDYADVRNGG
IISINVAKQALSMLDVDDAGFDYLDRKLLSAVIERFDGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRIA
TSQTYRHFGLQKLSD

Nucleotide


Download         Length: 1008 bp        

>NTDB_id=24607 NTHI_RS02050 WP_005649027.1 412606..413613(-) (ruvB) [Haemophilus influenzae 86-028NP]
ATGATTGAAGCAGATAGAATTATTAGCGGGCAAGCTAAGGTTGATGAAGATGTTATCGACCGTGCTATTCGTCCTAAACT
ATTAGCAGATTATGTTGGGCAGCCGCAAGTACGCGAGCAGATGGATATTTTCATCAAGGCAGCCAAACTACGTCAAGATG
CCTTAGATCATTTATTGATTTTTGGCCCTCCAGGTTTGGGAAAAACAACGCTTGCTAATATTGTGGCAAATGAAATGGGC
GTGAATATTCGTACGACATCAGGGCCTGTATTAGAAAAAGCGGGAGATTTAGCCGCAATGCTAACCAATCTTGAACCGCA
TGATGTGTTATTTATTGATGAAATCCATCGACTTTCCCCTGCTATTGAAGAAGTCCTTTATCCAGCAATGGAAGACTATC
AGTTGGATATTATGATTGGCGAAGGACCCGCTGCTCGTTCCATTAAATTAGATTTGCCCCCTTTTACTTTGGTTGGTGCG
ACCACTAGAGCGGGTTCTTTGACTTCTCCATTGCGTGATCGTTTTGGTATTGTGCAACGTTTGGAATTCTATTCTGTAGA
AGATTTAACATCTATCGTTGCAAGAAGTGCGGACTGTTTAAATCTTGAATTAGAACAACAAGCCGCTTTTGAGGTGGCTC
GTCGTTCACGAGGCACGCCTCGAATTGCAAACCGTTTATTACGACGTGTGCGTGATTATGCAGATGTACGTAATGGCGGT
ATTATTTCTATAAATGTGGCAAAACAAGCGCTTTCAATGCTAGATGTAGACGATGCTGGATTTGATTATTTAGATAGAAA
GTTGTTGTCTGCAGTTATTGAGCGTTTTGATGGTGGCCCTGTGGGGCTAGATAATCTTGCTGCTGCAATTGGCGAAGAAC
GTGATACCATTGAAGATGTTTTAGAGCCTTATTTGATTCAACAGGGGTTTCTACAAAGAACGCCGCGTGGCCGTATTGCA
ACATCGCAAACTTATCGTCATTTTGGTTTGCAGAAATTATCAGACTAG

Domains

Predicted by InterProScan.

Holliday junction DNA helicase RuvB P-loop domain (RuvB_N)

(23-181)

RuvB C-terminal winged helix domain (WHD_RuvB)

(259-328)

RuvB AAA lid domain (AAA_lid_4)

(184-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvB Bacillus subtilis subsp. subtilis str. 168

62.385

97.612

0.609
  ruvB Streptococcus pneumoniae TIGR4

57.975

97.313

0.564
  ruvB Streptococcus pneumoniae R6

57.975

97.313

0.564
  ruvB Streptococcus pneumoniae D39

57.975

97.313

0.564
  ruvB Helicobacter pylori 26695

54.633

93.433

0.51
  ruvB Synechocystis sp. PCC 6803

55.016

92.239

0.507

Multiple sequence alignment