Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   STR_RS07590 Genome accession   NC_006449
Coordinates   1436917..1439016 (-) Length   699 a.a.
NCBI ID   WP_011227488.1    Uniprot ID   -
Organism   Streptococcus thermophilus CNRZ1066     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1431917..1444016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STR_RS07560 (str1608) pptB 1432386..1433420 (-) 1035 WP_373867015.1 ABC transporter permease Regulator
  STR_RS07565 (str1609) pptA 1433420..1434151 (-) 732 WP_002951673.1 ABC transporter ATP-binding protein Regulator
  STR_RS07570 (str1610) - 1434216..1434635 (+) 420 WP_011227486.1 HIT family protein -
  STR_RS07575 (str1611) - 1434632..1434940 (+) 309 WP_011227487.1 hypothetical protein -
  STR_RS11395 (str1612) - 1435492..1435662 (-) 171 WP_011226439.1 hypothetical protein -
  STR_RS07585 (str1613) - 1435732..1436367 (-) 636 WP_011226440.1 DUF4230 domain-containing protein -
  STR_RS11585 - 1436386..1436511 (-) 126 WP_011681534.1 hypothetical protein -
  STR_RS07590 (str1614) clpE 1436917..1439016 (-) 2100 WP_011227488.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  STR_RS07595 (str1615) - 1439731..1440822 (-) 1092 WP_011227489.1 nucleotidyltransferase -
  STR_RS07600 (str1616) - 1440829..1441569 (-) 741 WP_309252055.1 class I SAM-dependent methyltransferase -
  STR_RS07605 (str1617) rsfS 1441894..1442247 (-) 354 WP_011227491.1 ribosome silencing factor -
  STR_RS07610 (str1618) yqeK 1442271..1442861 (-) 591 WP_002951696.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  STR_RS07615 (str1619) - 1442858..1443490 (-) 633 WP_011226445.1 nicotinate-nucleotide adenylyltransferase -
  STR_RS07620 (str1620) yhbY 1443594..1443911 (-) 318 WP_002951701.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77196.10 Da        Isoelectric Point: 4.8262

>NTDB_id=24385 STR_RS07590 WP_011227488.1 1436917..1439016(-) (clpE) [Streptococcus thermophilus CNRZ1066]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESIERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTIIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=24385 STR_RS07590 WP_011227488.1 1436917..1439016(-) (clpE) [Streptococcus thermophilus CNRZ1066]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGCAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCATAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAATCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAGGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(606-676)

AAA lid domain (AAA_lid_9)

(255-349)

AAA domain (Cdc48 subfamily) (AAA_2)

(439-599)

ATPase family associated with various cellular activities (AAA) (AAA)

(114-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.781

100

0.468
  clpC Lactococcus lactis subsp. cremoris KW2

48.906

91.559

0.448
  clpE Streptococcus pneumoniae D39

48.973

90.558

0.443
  clpE Streptococcus pneumoniae Rx1

48.973

90.558

0.443
  clpE Streptococcus pneumoniae R6

48.973

90.558

0.443
  clpE Streptococcus pneumoniae TIGR4

48.892

90.415

0.442
  clpC Bacillus subtilis subsp. subtilis str. 168

46.13

92.418

0.426
  clpC Streptococcus thermophilus LMD-9

43.417

91.273

0.396
  clpC Streptococcus thermophilus LMG 18311

43.26

91.273

0.395
  clpC Streptococcus pneumoniae TIGR4

43.499

89.127

0.388
  clpC Streptococcus pneumoniae Rx1

43.499

89.127

0.388
  clpC Streptococcus pneumoniae D39

43.499

89.127

0.388
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.436

88.269

0.383
  clpC Streptococcus mutans UA159

43.156

88.841

0.383

Multiple sequence alignment