Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   CGP92_RS07855 Genome accession   NZ_CP022896
Coordinates   1593952..1594263 (-) Length   103 a.a.
NCBI ID   WP_000472257.1    Uniprot ID   A0A115HMG3
Organism   Staphylococcus aureus strain 277     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1588952..1599263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGP92_RS07820 (CGP92_01450) gcvPA 1589454..1590800 (-) 1347 WP_063636320.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  CGP92_RS07825 (CGP92_01451) gcvT 1590820..1591911 (-) 1092 WP_000093347.1 glycine cleavage system aminomethyltransferase GcvT -
  CGP92_RS07830 (CGP92_01452) - 1592070..1592594 (-) 525 WP_115300159.1 shikimate kinase -
  CGP92_RS07835 - 1592584..1592730 (-) 147 WP_001789879.1 hypothetical protein -
  CGP92_RS07840 (CGP92_01453) comGF 1592827..1593324 (-) 498 WP_001794055.1 competence type IV pilus minor pilin ComGF Machinery gene
  CGP92_RS07845 (CGP92_01454) comGE 1593242..1593541 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  CGP92_RS07850 (CGP92_01455) comGD 1593528..1593974 (-) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  CGP92_RS07855 (CGP92_01456) comGC 1593952..1594263 (-) 312 WP_000472257.1 competence type IV pilus major pilin ComGC Machinery gene
  CGP92_RS07860 (CGP92_01457) comGB 1594277..1595347 (-) 1071 WP_000776412.1 competence type IV pilus assembly protein ComGB Machinery gene
  CGP92_RS07865 (CGP92_01458) comGA 1595319..1596293 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  CGP92_RS07870 (CGP92_01459) - 1596345..1596968 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  CGP92_RS07875 (CGP92_01460) - 1596965..1597294 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  CGP92_RS07880 (CGP92_01461) - 1597294..1598280 (-) 987 WP_000161314.1 ROK family glucokinase -
  CGP92_RS07885 - 1598277..1598480 (-) 204 WP_000087561.1 YqgQ family protein -

Sequence

Protein


Download         Length: 103 a.a.        Molecular weight: 11373.39 Da        Isoelectric Point: 7.8600

>NTDB_id=242865 CGP92_RS07855 WP_000472257.1 1593952..1594263(-) (comGC) [Staphylococcus aureus strain 277]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEEQKTCKSGETITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=242865 CGP92_RS07855 WP_000472257.1 1593952..1594263(-) (comGC) [Staphylococcus aureus strain 277]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGAGCAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(6-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A115HMG3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus N315

99.029

100

0.99
  comGC Staphylococcus aureus MW2

99.029

100

0.99
  comGC/cglC Streptococcus mitis SK321

48.039

99.029

0.476
  comGC/cglC Streptococcus pneumoniae R6

47.059

99.029

0.466
  comGC/cglC Streptococcus pneumoniae D39

47.059

99.029

0.466
  comGC/cglC Streptococcus pneumoniae TIGR4

47.059

99.029

0.466
  comGC/cglC Streptococcus pneumoniae Rx1

47.059

99.029

0.466
  comGC/cglC Streptococcus mitis NCTC 12261

52.326

83.495

0.437
  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408
  comYC Streptococcus suis isolate S10

50

75.728

0.379
  comYC Streptococcus mutans UA140

50

73.786

0.369
  comYC Streptococcus mutans UA159

50

73.786

0.369
  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369
  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369

Multiple sequence alignment