Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CHF41_RS03720 Genome accession   NZ_CP022680
Coordinates   734845..735576 (+) Length   243 a.a.
NCBI ID   WP_119876051.1    Uniprot ID   -
Organism   Streptococcus respiraculi strain HTS25     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 729845..740576
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CHF41_RS03700 - 730789..730998 (+) 210 WP_075098784.1 hypothetical protein -
  CHF41_RS03705 - 731094..731843 (-) 750 WP_119876048.1 amino acid ABC transporter ATP-binding protein -
  CHF41_RS03710 - 731836..733401 (-) 1566 WP_119876049.1 ABC transporter substrate-binding protein/permease -
  CHF41_RS03715 - 733529..734368 (+) 840 WP_119876050.1 undecaprenyl-diphosphate phosphatase -
  CHF41_RS03720 mecA 734845..735576 (+) 732 WP_119876051.1 adaptor protein MecA Regulator
  CHF41_RS03725 - 735573..736745 (+) 1173 WP_119876052.1 glycosyltransferase family 4 protein -
  CHF41_RS03730 sufC 736848..737618 (+) 771 WP_119876053.1 Fe-S cluster assembly ATPase SufC -
  CHF41_RS03735 sufD 737648..738910 (+) 1263 WP_119876054.1 Fe-S cluster assembly protein SufD -
  CHF41_RS03740 - 738914..740143 (+) 1230 WP_119876055.1 cysteine desulfurase -
  CHF41_RS03745 sufU 740130..740561 (+) 432 WP_119876056.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28149.80 Da        Isoelectric Point: 3.9946

>NTDB_id=241564 CHF41_RS03720 WP_119876051.1 734845..735576(+) (mecA) [Streptococcus respiraculi strain HTS25]
MKMKQISDSTLKITIKMEDLEERGMEIADFLVPQEKTEEFFYTVLDELDLPVTFRESGMLSFRVTPKPDKVDIFVTKSDI
DQNLNFDDFADMADLDEISQMTPDEFLKTLEKTIREKSAGDDKAVQYLEQVEADELDVDEVDTENRQYIYYILDFANLQE
AVQFVSLVDFTIEESELYKMNGRYYMTVLINIENRSTRYPDYILSRMLEHADDTSISRAVLQEHGVLLLPVGAIEELGKV
SLV

Nucleotide


Download         Length: 732 bp        

>NTDB_id=241564 CHF41_RS03720 WP_119876051.1 734845..735576(+) (mecA) [Streptococcus respiraculi strain HTS25]
ATGAAGATGAAACAAATTAGTGATTCGACCTTGAAAATCACGATTAAAATGGAGGACTTAGAAGAACGCGGAATGGAGAT
TGCGGACTTTCTCGTCCCGCAAGAAAAGACAGAGGAATTTTTCTATACAGTATTGGATGAATTGGATCTGCCAGTAACCT
TTCGTGAAAGTGGCATGCTTAGTTTTCGAGTGACGCCAAAGCCAGACAAGGTGGATATTTTTGTCACCAAGTCAGACATC
GATCAAAACTTAAATTTTGATGATTTTGCGGATATGGCGGATTTAGATGAGATTTCGCAGATGACGCCAGATGAGTTTTT
AAAGACACTTGAAAAGACCATTCGAGAAAAGAGTGCAGGGGATGATAAGGCGGTTCAGTACTTGGAGCAAGTCGAAGCAG
ATGAATTGGACGTTGACGAAGTGGATACAGAAAATCGTCAGTACATTTACTATATTCTGGATTTTGCTAATCTACAGGAA
GCTGTTCAATTTGTCTCTCTAGTTGATTTTACCATTGAAGAATCAGAGCTCTATAAGATGAATGGTCGTTACTATATGAC
TGTCTTGATTAATATTGAAAATCGTTCAACTCGCTACCCGGACTATATCTTGTCACGAATGTTAGAGCATGCAGACGATA
CATCCATTTCACGTGCGGTGCTTCAAGAGCACGGAGTTTTGTTGCTTCCTGTGGGTGCGATTGAAGAGCTTGGGAAGGTG
AGCTTGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

58.367

100

0.588
  mecA Streptococcus pneumoniae D39

58.367

100

0.588
  mecA Streptococcus pneumoniae R6

58.367

100

0.588
  mecA Streptococcus pneumoniae TIGR4

58.367

100

0.588
  mecA Streptococcus mutans UA159

53.112

99.177

0.527
  mecA Streptococcus thermophilus LMD-9

46.939

100

0.473
  mecA Streptococcus thermophilus LMG 18311

46.531

100

0.469

Multiple sequence alignment