Detailed information NTG0241152

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FORC61_RS13650
• Genome accession: NZ_CP022607
• Coordinates: 2630759..2631646 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain FORC_061
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2625759..2636646

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC61_RS13615	-	2625777..2625869 (+)	93	WP_010956583.1	hypothetical protein	-
FORC61_RS13620 (FORC61_2406)	-	2625977..2626474 (-)	498	WP_001065269.1	glutathione peroxidase	-
FORC61_RS13625	-	2626484..2626744 (-)	261	WP_001789910.1	hypothetical protein	-
FORC61_RS13635	-	2627126..2627239 (-)	114	Protein_2534	hypothetical protein	-
FORC61_RS13640 (FORC61_2407)	-	2627898..2629898 (-)	2001	WP_000776739.1	ABC transporter permease	-
FORC61_RS13645 (FORC61_2408)	-	2629895..2630650 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FORC61_RS13650 (FORC61_2409)	braS	2630759..2631646 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FORC61_RS13655 (FORC61_2410)	braR	2631657..2632322 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FORC61_RS13660 (FORC61_2411)	-	2632348..2632548 (-)	201	WP_000604727.1	hypothetical protein	-
FORC61_RS13665 (FORC61_2412)	-	2632746..2634170 (+)	1425	WP_000953762.1	alkaline phosphatase	-
FORC61_RS14230	-	2634240..2634350 (+)	111	WP_001791296.1	hypothetical protein	-
FORC61_RS13675 (FORC61_2413)	-	2634453..2634908 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FORC61_RS13680 (FORC61_2414)	-	2635153..2635914 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=241152 FORC61_RS13650 WP_000143420.1 2630759..2631646(-) (braS) [Staphylococcus aureus strain FORC_061]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=241152 FORC61_RS13650 WP_000143420.1 2630759..2631646(-) (braS) [Staphylococcus aureus strain FORC_061]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993