Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   Sp14A_RS08705 Genome accession   NZ_CP022601
Coordinates   1693009..1694892 (-) Length   627 a.a.
NCBI ID   WP_115130712.1    Uniprot ID   A0A345VLU1
Organism   Streptococcus pluranimalium strain 14A0014     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1688009..1699892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS08680 (Sp14A_17950) - 1688713..1689072 (-) 360 WP_104968357.1 S1 RNA-binding domain-containing protein -
  Sp14A_RS08685 (Sp14A_17960) - 1689072..1690472 (-) 1401 WP_115130710.1 Cof-type HAD-IIB family hydrolase -
  Sp14A_RS08690 (Sp14A_17970) - 1690520..1691158 (-) 639 WP_104968359.1 response regulator transcription factor -
  Sp14A_RS08695 (Sp14A_17980) - 1691151..1692149 (-) 999 WP_115130711.1 sensor histidine kinase -
  Sp14A_RS08700 (Sp14A_17990) liaF 1692146..1692844 (-) 699 WP_104968361.1 cell wall-active antibiotics response protein LiaF -
  Sp14A_RS08705 (Sp14A_18000) stkP/pknB 1693009..1694892 (-) 1884 WP_115130712.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  Sp14A_RS08710 (Sp14A_18010) - 1694892..1695629 (-) 738 WP_115131188.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  Sp14A_RS08715 (Sp14A_18020) rsmB 1695678..1697000 (-) 1323 WP_115130713.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  Sp14A_RS08720 (Sp14A_18030) fmt 1696990..1697931 (-) 942 WP_115130714.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68189.35 Da        Isoelectric Point: 4.7694

>NTDB_id=241070 Sp14A_RS08705 WP_115130712.1 1693009..1694892(-) (stkP/pknB) [Streptococcus pluranimalium strain 14A0014]
MIQIGKLFAGRYRILKSIGRGGMADVYLAHDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLAMEYVNGPDLKKYIQDHAPLSNTETVRIMSEVLSAMQLAHQKGIVHRDLKPQNVLLTKDGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTCHIPFDGDSAVTIALQHFQKPLPSIIFENRNVP
QALENVVIKATAKKLGDRYVSTTDMYQDLGTSLDSRRARESKLVFQDTTDTKTLPKIEPSPVKEAPKAAVAPDSVEVPKE
KEASKKEASTPPSSKKSKKPFWQRLFRFFILALVLLLAGFAFFFMSSSNDSATVPDVSGQTIQEAQATLEEAGLTVGAVS
RKESDSVEEGKVISTTPKSGTTQKEGSEVDLLVSKGSKRFVMTDYTGMSYRDAVSDLTENYGLSKNQIVKKEVTNNQYEP
GEIISQTPEAGEDFNPSGNDKIIFEVATASTVTIPTLVGYSYADAKNALLDLGFKASQIQTDSDQPSSSATVYAQYPYAG
TSVELSSGETVTLYLTTPEPSSTQPSSSSEEIDTDSSNQTSSSSSSSSSNHSTEATGDANSQPETTD

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=241070 Sp14A_RS08705 WP_115130712.1 1693009..1694892(-) (stkP/pknB) [Streptococcus pluranimalium strain 14A0014]
ATGATCCAAATCGGCAAATTATTTGCTGGGCGTTATCGTATTTTAAAATCTATCGGTCGCGGTGGTATGGCTGATGTTTA
TTTGGCACATGATTTGATTTTGGATAATGAAGAAGTAGCGATTAAGGTGCTTCGAACCAATTATCAAACAGATCAAATTG
CAGTCGCGCGTTTCCAGAGAGAAGCGCGTGCGATGGCTGAATTAAACCATCCTAACATTGTAGCTATCAGAGATATCGGC
GAAGAAGATGGACAACAATTTCTTGCCATGGAATACGTTAATGGTCCAGATTTAAAGAAGTATATTCAAGATCATGCACC
TCTTTCTAATACTGAGACAGTTCGTATCATGAGTGAGGTGTTATCAGCTATGCAGCTGGCTCATCAAAAAGGAATTGTTC
ATCGTGACTTGAAGCCACAGAATGTTCTTTTGACAAAAGACGGAGTAGCTAAGGTAACTGATTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTTTGACACAGACAAATTCGATGTTAGGAAGTGTTCATTACTTGTCACCAGAGCAAGCACGAGGCTC
TAAAGCAACGATACAAAGTGATATTTATGCTATGGGTATCATGTTGTTTGAAATGTTGACTTGTCATATCCCATTTGATG
GTGATAGTGCTGTTACGATTGCGTTGCAACACTTTCAGAAACCTTTGCCATCGATTATTTTTGAAAATCGAAATGTTCCA
CAAGCTTTGGAGAATGTTGTTATCAAAGCAACTGCTAAAAAGCTCGGAGATCGCTATGTATCAACGACCGATATGTATCA
AGATTTAGGGACATCCCTAGATTCGCGCCGTGCTAGAGAATCAAAGTTAGTTTTTCAGGATACAACAGATACTAAGACAT
TACCTAAAATTGAGCCTTCACCTGTTAAAGAGGCACCTAAAGCAGCAGTTGCTCCGGATAGTGTCGAAGTGCCTAAAGAA
AAGGAAGCTTCTAAAAAAGAAGCCTCTACACCGCCGTCATCTAAAAAGTCTAAGAAACCTTTTTGGCAACGTCTATTCAG
ATTTTTCATTTTGGCCCTCGTTTTATTACTAGCCGGTTTTGCATTCTTCTTTATGTCAAGTAGCAATGATAGTGCAACAG
TTCCTGATGTCTCAGGGCAAACAATCCAAGAAGCTCAAGCGACTCTAGAAGAGGCTGGTTTGACTGTAGGAGCTGTTTCT
CGTAAAGAAAGTGACAGTGTTGAGGAAGGAAAGGTCATTTCAACAACACCGAAATCAGGAACCACTCAAAAAGAGGGAAG
CGAAGTTGATCTACTAGTTTCAAAAGGTTCTAAACGCTTTGTTATGACAGATTATACCGGGATGTCATATAGGGATGCTG
TTAGTGATTTGACGGAAAATTATGGTTTGTCTAAAAATCAAATTGTCAAAAAAGAAGTTACAAATAATCAGTATGAACCG
GGAGAAATTATTAGTCAGACTCCAGAAGCTGGCGAAGATTTTAACCCTTCAGGTAATGATAAGATTATTTTTGAAGTAGC
AACAGCTTCAACAGTAACAATACCAACCTTGGTTGGTTACAGTTATGCAGATGCCAAGAATGCTTTATTAGACCTAGGAT
TTAAAGCTTCTCAGATTCAGACAGATTCAGATCAACCGTCGTCATCGGCAACGGTTTATGCACAATACCCATATGCAGGG
ACGTCTGTTGAACTCTCATCTGGAGAAACGGTAACATTGTATCTAACAACTCCTGAGCCATCATCGACGCAACCGTCATC
ATCTTCTGAGGAGATAGATACGGATAGCAGTAATCAGACCTCTTCATCAAGTAGTTCTTCTAGTTCCAACCATTCAACGG
AAGCAACAGGTGATGCAAACAGCCAACCAGAAACTACTGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(441-507)

PASTA domain (PASTA)

(512-576)

PASTA domain (PASTA)

(373-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A345VLU1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

62.969

93.461

0.589
  pknB Streptococcus mutans UA159

61.017

94.099

0.574
  stkP Streptococcus pneumoniae TIGR4

52.57

96.172

0.506
  stkP Streptococcus pneumoniae D39

53.299

94.258

0.502
  stkP Streptococcus pneumoniae R6

53.299

94.258

0.502
  stkP Streptococcus pneumoniae Rx1

53.13

94.258

0.501

Multiple sequence alignment