Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   Sp14A_RS07675 Genome accession   NZ_CP022601
Coordinates   1507755..1508471 (-) Length   238 a.a.
NCBI ID   WP_115130564.1    Uniprot ID   A0A345VLA2
Organism   Streptococcus pluranimalium strain 14A0014     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1502755..1513471
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS07660 (Sp14A_15900) - 1503887..1504768 (-) 882 WP_115130562.1 substrate-binding domain-containing protein -
  Sp14A_RS07665 (Sp14A_15920) - 1505010..1506355 (+) 1346 WP_205407072.1 IS3 family transposase -
  Sp14A_RS07670 (Sp14A_15930) - 1506415..1507755 (-) 1341 WP_115130563.1 ATP-binding protein -
  Sp14A_RS07675 (Sp14A_15940) vicR 1507755..1508471 (-) 717 WP_115130564.1 response regulator transcription factor Regulator
  Sp14A_RS07680 (Sp14A_15950) - 1508608..1509456 (-) 849 WP_115130565.1 aldo/keto reductase -
  Sp14A_RS07685 (Sp14A_15960) - 1509797..1510312 (+) 516 WP_104968221.1 RNA polymerase sigma factor -
  Sp14A_RS07690 (Sp14A_15970) - 1510290..1511261 (+) 972 WP_104968222.1 anti sigma factor C-terminal domain-containing protein -
  Sp14A_RS07695 (Sp14A_15980) - 1511841..1512038 (+) 198 WP_104968223.1 hypothetical protein -
  Sp14A_RS07700 (Sp14A_15990) - 1512174..1513220 (-) 1047 WP_104968224.1 LLM class flavin-dependent oxidoreductase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27456.68 Da        Isoelectric Point: 5.4736

>NTDB_id=241060 Sp14A_RS07675 WP_115130564.1 1507755..1508471(-) (vicR) [Streptococcus pluranimalium strain 14A0014]
MQKRVLIVDDEPHILTLVSYHLAKEGFEVTTVDDGRSALDLGQGQPFDFIVLDIMLPQLDGVEVCKRLRKGGIETPILML
SAKGEEFDKVLALELGADDYMTKPFSPRELLARIKAILRRTEKNQLSELPQEEDQSDTKFQVADLSVYLERHQIYKADRE
ISLTPKEFELLVYLLKHPRMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPAIIKTVRGYGYKFEGDK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=241060 Sp14A_RS07675 WP_115130564.1 1507755..1508471(-) (vicR) [Streptococcus pluranimalium strain 14A0014]
ATGCAAAAGCGTGTTTTAATCGTGGATGATGAGCCACATATTCTCACTTTGGTTTCTTACCATTTAGCTAAGGAAGGTTT
TGAGGTGACGACTGTAGACGATGGTCGTTCTGCTCTAGACTTGGGACAAGGTCAGCCCTTTGATTTTATTGTTTTAGATA
TTATGTTGCCACAACTTGATGGTGTTGAAGTTTGTAAAAGACTGCGAAAGGGCGGTATCGAAACCCCTATCCTCATGCTA
TCAGCTAAGGGCGAGGAATTTGATAAGGTTTTAGCTCTGGAATTAGGGGCGGATGACTACATGACCAAGCCCTTTAGTCC
GCGGGAACTTTTGGCTAGAATCAAGGCAATCCTGCGTCGGACTGAGAAAAATCAACTGTCAGAATTGCCCCAAGAAGAAG
ACCAGTCTGATACGAAATTTCAAGTTGCAGACTTATCGGTCTATTTGGAGCGTCATCAGATTTACAAGGCAGATCGAGAG
ATTAGCTTGACACCTAAAGAGTTTGAACTCTTGGTTTATCTTTTGAAGCATCCTCGTATGACGCTGACCAGAGAACGCCT
GTTGGAGCGGATTTGGGGCTATGATTTTGGGCAGGAGACCCGTTTAGTGGATGTGCATATCGGTAAGTTACGTGAAAAAA
TCGAGGATAATCCCAAAGCACCTGCCATTATCAAAACAGTCAGAGGTTACGGCTACAAGTTTGAAGGAGACAAGTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-234)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A345VLA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

50.435

96.639

0.487
  micA Streptococcus pneumoniae Cp1015

49.565

96.639

0.479
  covR Streptococcus salivarius strain HSISS4

41.81

97.479

0.408
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.126

97.059

0.399
  scnR Streptococcus mutans UA159

37.021

98.739

0.366

Multiple sequence alignment