Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   Sp14A_RS05900 Genome accession   NZ_CP022601
Coordinates   1118448..1119119 (-) Length   223 a.a.
NCBI ID   WP_104967889.1    Uniprot ID   A0A2L0D3Z7
Organism   Streptococcus pluranimalium strain 14A0014     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1113448..1124119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS05875 (Sp14A_12250) - 1113692..1114081 (-) 390 WP_115130295.1 cytidine deaminase -
  Sp14A_RS05880 (Sp14A_12270) - 1114674..1115261 (-) 588 WP_104967885.1 class I SAM-dependent methyltransferase -
  Sp14A_RS05885 (Sp14A_12280) coaA 1115388..1116308 (+) 921 WP_115130296.1 type I pantothenate kinase -
  Sp14A_RS05890 (Sp14A_12290) rpsT 1116361..1116609 (+) 249 WP_115130297.1 30S ribosomal protein S20 -
  Sp14A_RS05895 (Sp14A_12300) ciaH 1117151..1118455 (-) 1305 WP_115130298.1 HAMP domain-containing sensor histidine kinase Regulator
  Sp14A_RS05900 (Sp14A_12310) ciaR 1118448..1119119 (-) 672 WP_104967889.1 response regulator transcription factor Regulator
  Sp14A_RS05905 (Sp14A_12320) - 1119365..1121899 (-) 2535 WP_115130299.1 M1 family metallopeptidase -
  Sp14A_RS05910 (Sp14A_12330) phoU 1122021..1122674 (-) 654 WP_115130300.1 phosphate signaling complex protein PhoU -
  Sp14A_RS05915 (Sp14A_12340) pstB 1122700..1123458 (-) 759 WP_115130301.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25377.22 Da        Isoelectric Point: 4.4478

>NTDB_id=241055 Sp14A_RS05900 WP_104967889.1 1118448..1119119(-) (ciaR) [Streptococcus pluranimalium strain 14A0014]
MIKLLLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLTDHTIVYGNISVDTTINRVTVDGKEVEFLGKEFELLMY
FLQNQNVILPKTQIFDRLWGFDSDTTLSVVEVYVSKIRKKLKGTSFADHLQTLRSVGYILKDA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=241055 Sp14A_RS05900 WP_104967889.1 1118448..1119119(-) (ciaR) [Streptococcus pluranimalium strain 14A0014]
ATGATAAAATTACTCTTGGTTGAAGATGATTTGAGTTTGTCCAATTCTGTATTTGATTTTCTGGATGATTTTGCAGATGT
GATGCAGGTCTTTGATGGGGAAGAAGGATTGTATGAAGCTGAATCTGGCGTTTATGATCTTATTTTACTAGATCTTATGC
TTCCAGAGAAAAATGGTTTTCAAGTGCTAAAAGAGCTTCGAGAAAAAGGGATAACAACACCTGTTTTAATTATGACAGCA
AAGGAAGGACTGGATGATAAGGGACATGGTTTTGAGTTAGGAGCAGATGATTATTTAACTAAGCCATTTTATCTAGAAGA
ATTAAAAATGAGAATTCAAGCCTTACTTAAACGTTCTGGAAAGTTGACTGACCACACTATCGTATACGGTAATATTAGCG
TTGACACGACAATTAATCGTGTTACAGTAGATGGCAAAGAAGTAGAATTTTTAGGTAAAGAATTTGAATTGTTAATGTAC
TTTCTACAAAACCAAAATGTTATTTTACCTAAAACACAGATTTTTGATCGTTTATGGGGATTTGATAGCGATACAACGCT
TTCGGTTGTTGAAGTTTATGTGTCAAAAATCCGTAAAAAACTTAAAGGAACGAGTTTTGCAGATCATTTACAGACTTTAA
GAAGTGTTGGTTATATTTTAAAAGATGCATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D3Z7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

87.444

100

0.874
  ciaR Streptococcus pneumoniae Rx1

86.547

100

0.865
  ciaR Streptococcus pneumoniae D39

86.547

100

0.865
  ciaR Streptococcus pneumoniae R6

86.547

100

0.865
  ciaR Streptococcus pneumoniae TIGR4

86.547

100

0.865
  covR Lactococcus lactis subsp. lactis strain DGCC12653

35.841

100

0.363

Multiple sequence alignment