Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   Sp14A_RS05895 Genome accession   NZ_CP022601
Coordinates   1117151..1118455 (-) Length   434 a.a.
NCBI ID   WP_115130298.1    Uniprot ID   A0A345VK92
Organism   Streptococcus pluranimalium strain 14A0014     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1112151..1123455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS05870 (Sp14A_12240) - 1112570..1113619 (-) 1050 WP_104967883.1 BMP family protein -
  Sp14A_RS05875 (Sp14A_12250) - 1113692..1114081 (-) 390 WP_115130295.1 cytidine deaminase -
  Sp14A_RS05880 (Sp14A_12270) - 1114674..1115261 (-) 588 WP_104967885.1 class I SAM-dependent methyltransferase -
  Sp14A_RS05885 (Sp14A_12280) coaA 1115388..1116308 (+) 921 WP_115130296.1 type I pantothenate kinase -
  Sp14A_RS05890 (Sp14A_12290) rpsT 1116361..1116609 (+) 249 WP_115130297.1 30S ribosomal protein S20 -
  Sp14A_RS05895 (Sp14A_12300) ciaH 1117151..1118455 (-) 1305 WP_115130298.1 HAMP domain-containing sensor histidine kinase Regulator
  Sp14A_RS05900 (Sp14A_12310) ciaR 1118448..1119119 (-) 672 WP_104967889.1 response regulator transcription factor Regulator
  Sp14A_RS05905 (Sp14A_12320) - 1119365..1121899 (-) 2535 WP_115130299.1 M1 family metallopeptidase -
  Sp14A_RS05910 (Sp14A_12330) phoU 1122021..1122674 (-) 654 WP_115130300.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 49883.42 Da        Isoelectric Point: 9.4851

>NTDB_id=241054 Sp14A_RS05895 WP_115130298.1 1117151..1118455(-) (ciaH) [Streptococcus pluranimalium strain 14A0014]
MHKYIQKKIHSDNFKPFIHFMMVFTAIFFVMTIIILQIMRLGLYSSTDNSLKRARYSAASYIAMTMARNYSWSSDGDGFG
ITIDPSKFKYNDDLAVLDIIVFDRYGEVINTVDAYSEFSSIKLNKKQLNRIVKETHINTYGHAENYRSVTLEVTDLAYPQ
VKYISFLASTRQLDEAFDRYVNVIISIMIIFWLISVITSVYLAKWSRKPIIASYEKQKSFVENASHELRTPLAVLQNRLE
TLFRKPNDTILEHSESIAASLDEVRNMRMLTTNLLNLARRDDGIDPNIEDISPTFFDDVFKNYQLIAQENDKELMVSNHL
KRPIKSDKTLIKQLMTILVDNALKYTKKQGVISISVETKGRRLWLRVSDNGLGISDDDKSKIFDRFYRVDKARTRQSGGF
GLGLSLAKQIVDTLGGEITVKDNTPQGTIFDIFL

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=241054 Sp14A_RS05895 WP_115130298.1 1117151..1118455(-) (ciaH) [Streptococcus pluranimalium strain 14A0014]
ATGCATAAATACATACAAAAAAAAATTCATTCTGATAATTTCAAGCCCTTTATCCATTTTATGATGGTATTCACTGCTAT
TTTCTTTGTGATGACGATTATTATTTTGCAGATTATGAGACTTGGTCTCTACTCTTCAACGGATAATAGTCTGAAAAGAG
CTAGGTACTCTGCGGCTAGTTATATTGCAATGACTATGGCTAGGAATTACTCTTGGAGCTCAGATGGAGATGGTTTCGGT
ATTACAATCGATCCTAGTAAGTTTAAATACAATGATGATCTGGCTGTTTTAGATATTATTGTATTTGATAGATATGGAGA
GGTTATTAATACGGTTGATGCCTATTCTGAATTTTCAAGTATTAAGCTTAATAAAAAACAGCTCAATAGAATTGTTAAAG
AGACTCACATCAACACTTATGGACATGCTGAAAATTATCGCAGTGTCACGCTTGAAGTTACCGATTTAGCCTATCCTCAA
GTAAAATATATTAGTTTTCTAGCGAGTACGAGACAATTGGATGAGGCATTTGACCGCTATGTTAATGTTATTATAAGCAT
TATGATTATCTTTTGGTTGATATCAGTTATCACTAGTGTTTATCTAGCCAAGTGGAGTCGTAAACCAATCATTGCTAGTT
ATGAAAAACAAAAGAGCTTTGTTGAAAATGCCAGCCATGAATTAAGAACGCCCCTGGCTGTACTCCAAAATCGCTTAGAA
ACCTTGTTTAGAAAACCTAATGATACTATTCTTGAACATAGCGAGAGTATTGCAGCAAGTCTTGATGAAGTTAGAAATAT
GAGAATGTTAACGACAAATCTCTTAAACTTGGCTCGTCGTGATGATGGTATTGACCCTAATATAGAAGATATTTCACCAA
CATTTTTTGATGATGTCTTTAAAAATTACCAATTAATTGCTCAGGAGAATGACAAGGAGTTAATGGTATCAAATCATTTG
AAACGACCTATTAAATCAGATAAAACACTCATAAAACAGTTGATGACTATTTTAGTTGATAACGCCTTGAAATATACAAA
GAAGCAAGGGGTTATTAGTATTTCTGTTGAAACCAAGGGGCGCCGTTTGTGGTTGAGAGTATCAGATAATGGTTTAGGTA
TTTCAGATGATGATAAATCGAAAATCTTTGATCGATTTTACCGTGTTGATAAAGCAAGAACGAGACAATCTGGTGGATTT
GGTCTGGGTTTATCTCTTGCTAAGCAGATTGTAGATACTTTGGGTGGAGAGATAACAGTAAAAGATAATACACCTCAAGG
AACTATTTTTGATATTTTCTTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-433)

His Kinase A (phospho-acceptor) domain (HisKA)

(218-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A345VK92

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.207

98.848

0.585
  ciaH Streptococcus pneumoniae Rx1

48.387

100

0.484
  ciaH Streptococcus pneumoniae D39

48.387

100

0.484
  ciaH Streptococcus pneumoniae R6

48.387

100

0.484
  ciaH Streptococcus pneumoniae TIGR4

48.387

100

0.484

Multiple sequence alignment