Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   Sp14A_RS01380 Genome accession   NZ_CP022601
Coordinates   252040..252798 (+) Length   252 a.a.
NCBI ID   WP_115129644.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain 14A0014     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 247040..257798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS01355 (Sp14A_02790) - 248312..248815 (-) 504 WP_115129639.1 phosphatidylglycerophosphatase A -
  Sp14A_RS01360 (Sp14A_02800) - 249019..250335 (+) 1317 WP_115129640.1 FAD-containing oxidoreductase -
  Sp14A_RS01365 (Sp14A_02810) - 250345..250701 (+) 357 WP_115129641.1 DUF2200 domain-containing protein -
  Sp14A_RS01370 (Sp14A_02820) - 250906..251463 (+) 558 WP_115129642.1 DUF1697 domain-containing protein -
  Sp14A_RS01375 (Sp14A_02830) - 251464..251961 (+) 498 WP_115129643.1 phosphatase PAP2 family protein -
  Sp14A_RS01380 (Sp14A_02840) mecA 252040..252798 (+) 759 WP_115129644.1 adaptor protein MecA Regulator
  Sp14A_RS01385 (Sp14A_02850) - 252799..253956 (+) 1158 WP_115129645.1 MraY family glycosyltransferase -
  Sp14A_RS01390 (Sp14A_02860) sufC 254064..254834 (+) 771 WP_104967221.1 Fe-S cluster assembly ATPase SufC -
  Sp14A_RS01395 (Sp14A_02870) - 254847..255362 (+) 516 WP_115129646.1 GNAT family N-acetyltransferase -
  Sp14A_RS01400 (Sp14A_02880) sufD 255365..256627 (+) 1263 WP_115129647.1 Fe-S cluster assembly protein SufD -

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 28928.60 Da        Isoelectric Point: 4.2427

>NTDB_id=241036 Sp14A_RS01380 WP_115129644.1 252040..252798(+) (mecA) [Streptococcus pluranimalium strain 14A0014]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKNSGMLSFRVTPKKDRLDVFVTKSEI
DKDLNFDDLAALGDVSQMSPDEFFKTLEKSMLEKGDTEAHEKLKQMEEIVESAMTEQTSEADLVHEPTEDNAEQDSYTHY
VLQFPMLKDAVAFSKAIDFDIEASELYKFNGSYYITILVSLENKPAYYADLVHARLLEHSRGGQKTRAYLQEHGVRLLEG
YAVADLEGIKVV

Nucleotide


Download         Length: 759 bp        

>NTDB_id=241036 Sp14A_RS01380 WP_115129644.1 252040..252798(+) (mecA) [Streptococcus pluranimalium strain 14A0014]
ATGGAAATGAAACAAATTAGCGAAACAACGCTAAAAATCACGATTAGTATGGAAGATTTGGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTTATTCCTCAAGAAAAAACGGAAGAATTTTTTTATTCCGTGATGGACGAACTTGACTTACCAGATAACT
TCAAAAATAGTGGCATGTTGAGTTTTCGAGTGACACCTAAGAAAGATCGATTGGATGTTTTTGTAACCAAGTCTGAAATT
GATAAGGATTTAAACTTTGATGATTTAGCAGCCTTGGGTGATGTCTCTCAAATGTCTCCGGATGAATTCTTTAAGACATT
AGAAAAATCAATGTTGGAGAAGGGAGACACTGAAGCTCACGAGAAGTTAAAACAAATGGAAGAAATCGTGGAATCTGCGA
TGACAGAGCAAACATCAGAAGCAGACTTAGTCCATGAACCTACTGAAGATAATGCTGAACAAGACAGTTATACGCACTAT
GTGTTACAGTTTCCCATGCTGAAAGATGCCGTTGCTTTTTCAAAAGCGATTGACTTTGATATAGAAGCATCAGAACTGTA
TAAATTCAACGGCAGTTACTATATTACTATCTTGGTCAGTCTAGAAAATAAGCCCGCTTATTATGCCGACTTGGTTCACG
CTCGCTTGTTGGAGCACAGTCGTGGTGGTCAAAAAACAAGAGCCTATCTGCAAGAGCATGGCGTCCGTTTGCTTGAAGGC
TATGCGGTGGCTGATTTAGAAGGTATCAAGGTGGTCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

59.839

98.81

0.591
  mecA Streptococcus thermophilus LMD-9

55.512

100

0.56
  mecA Streptococcus thermophilus LMG 18311

54.724

100

0.552
  mecA Streptococcus pneumoniae Rx1

49.603

100

0.496
  mecA Streptococcus pneumoniae D39

49.603

100

0.496
  mecA Streptococcus pneumoniae R6

49.603

100

0.496
  mecA Streptococcus pneumoniae TIGR4

49.603

100

0.496

Multiple sequence alignment