Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   I3Y_RS20720 Genome accession   NZ_CP028379
Coordinates   4005843..4006967 (-) Length   374 a.a.
NCBI ID   WP_000228550.1    Uniprot ID   -
Organism   Escherichia coli O145 str. RM9872     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 4000843..4011967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3Y_RS20690 (I3Y_21190) yrdA 4002643..4003197 (+) 555 WP_022581407.1 gamma carbonic anhydrase family protein -
  I3Y_RS20695 (I3Y_21195) yrdB 4003173..4003430 (-) 258 WP_001070559.1 DUF1488 domain-containing protein -
  I3Y_RS20700 (I3Y_21200) aroE 4003427..4004245 (-) 819 WP_000451242.1 shikimate dehydrogenase -
  I3Y_RS20705 (I3Y_21205) tsaC 4004250..4004822 (-) 573 WP_001301437.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  I3Y_RS20710 (I3Y_21210) yrdD 4004827..4005369 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  I3Y_RS20715 (I3Y_21215) smg 4005398..4005871 (-) 474 WP_000460670.1 DUF494 family protein Smg -
  I3Y_RS20720 (I3Y_21220) dprA 4005843..4006967 (-) 1125 WP_000228550.1 DNA-protecting protein DprA Machinery gene
  I3Y_RS20725 (I3Y_21225) def 4007097..4007606 (+) 510 WP_000114984.1 peptide deformylase -
  I3Y_RS20730 (I3Y_21230) fmt 4007621..4008568 (+) 948 WP_000004448.1 methionyl-tRNA formyltransferase -
  I3Y_RS20735 (I3Y_21235) rsmB 4008614..4009903 (+) 1290 WP_000744779.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I3Y_RS20740 (I3Y_21240) trkA 4009925..4011301 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  I3Y_RS20745 (I3Y_21245) mscL 4011431..4011841 (+) 411 WP_000022441.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41002.96 Da        Isoelectric Point: 6.3366

>NTDB_id=240980 I3Y_RS20720 WP_000228550.1 4005843..4006967(-) (dprA) [Escherichia coli O145 str. RM9872]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=240980 I3Y_RS20720 WP_000228550.1 4005843..4006967(-) (dprA) [Escherichia coli O145 str. RM9872]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCACTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393

Multiple sequence alignment