Detailed information NTG0240587

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: CG712_RS07010
• Genome accession: NZ_CP022547
• Coordinates: 1320798..1321547 (+)
• Length: 249 a.a.
• NCBI ID: WP_096811807.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain B59671
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1315798..1326547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CG712_RS09985	-	1316372..1316542 (+)	171	WP_011680664.1	hypothetical protein	-
CG712_RS06985 (CG712_07035)	-	1316629..1316736 (+)	108	WP_084829946.1	LPXTG cell wall anchor domain-containing protein	-
CG712_RS06990 (CG712_07040)	-	1316824..1317564 (-)	741	WP_002949253.1	amino acid ABC transporter ATP-binding protein	-
CG712_RS06995 (CG712_07045)	-	1317564..1319114 (-)	1551	WP_096811805.1	ABC transporter substrate-binding protein/permease	-
CG712_RS07000 (CG712_07050)	-	1319317..1320171 (+)	855	WP_041828107.1	undecaprenyl-diphosphate phosphatase	-
CG712_RS07005 (CG712_07055)	-	1320317..1320532 (-)	216	WP_011226805.1	DUF3021 family protein	-
CG712_RS07010 (CG712_07060)	mecA	1320798..1321547 (+)	750	WP_096811807.1	adaptor protein MecA	Regulator
CG712_RS07015 (CG712_07065)	-	1321551..1322708 (+)	1158	WP_096811808.1	glycosyltransferase family 4 protein	-
CG712_RS07020 (CG712_07070)	sufC	1322873..1323643 (+)	771	WP_002947634.1	Fe-S cluster assembly ATPase SufC	-
CG712_RS07025 (CG712_07075)	sufD	1323680..1324942 (+)	1263	WP_002947640.1	Fe-S cluster assembly protein SufD	-
CG712_RS07030 (CG712_07080)	-	1324996..1326228 (+)	1233	WP_002949261.1	cysteine desulfurase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29199.78 Da
• Isoelectric Point: 4.1121

>NTDB_id=240587 CG712_RS07010 WP_096811807.1 1320798..1321547(+) (mecA) [Streptococcus thermophilus strain B59671]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALENNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKKVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=240587 CG712_RS07010 WP_096811807.1 1320798..1321547(+) (mecA) [Streptococcus thermophilus strain B59671]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAAATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGAAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMD-9	98.795	100	0.988
mecA	Streptococcus thermophilus LMG 18311	98.795	100	0.988
mecA	Streptococcus mutans UA159	57.787	97.992	0.566
mecA	Streptococcus pneumoniae Rx1	46.586	100	0.466
mecA	Streptococcus pneumoniae D39	46.586	100	0.466
mecA	Streptococcus pneumoniae R6	46.586	100	0.466
mecA	Streptococcus pneumoniae TIGR4	46.586	100	0.466