Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C7M28_RS11265 Genome accession   NZ_CP028215
Coordinates   2170883..2172085 (-) Length   400 a.a.
NCBI ID   WP_046381475.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM102750     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2165883..2177085
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M28_RS11240 (C7M28_02215) - 2166821..2168287 (-) 1467 WP_046381472.1 HAMP domain-containing sensor histidine kinase -
  C7M28_RS11245 (C7M28_02216) - 2168284..2168967 (-) 684 WP_038428106.1 response regulator transcription factor -
  C7M28_RS11250 (C7M28_02217) - 2169179..2170078 (+) 900 WP_046381473.1 PepSY domain-containing protein -
  C7M28_RS11255 (C7M28_02218) - 2170239..2170739 (+) 501 WP_046381474.1 PepSY domain-containing protein -
  C7M28_RS11260 - 2170736..2170862 (-) 127 Protein_2235 hypothetical protein -
  C7M28_RS11265 (C7M28_02219) htrA 2170883..2172085 (-) 1203 WP_046381475.1 serine protease HtrC Regulator
  C7M28_RS11270 (C7M28_02220) vicX 2172167..2172961 (-) 795 WP_046381476.1 MBL fold metallo-hydrolase Regulator
  C7M28_RS11275 (C7M28_02221) walI 2172983..2173825 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  C7M28_RS11280 (C7M28_02222) walH 2173812..2175179 (-) 1368 WP_042976993.1 WalRK two-component regulatory system regulator WalH -
  C7M28_RS11285 (C7M28_02223) walK 2175169..2177004 (-) 1836 WP_024572714.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42784.55 Da        Isoelectric Point: 5.7919

>NTDB_id=240206 C7M28_RS11265 WP_046381475.1 2170883..2172085(-) (htrA) [Bacillus subtilis strain SRCM102750]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQRNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=240206 C7M28_RS11265 WP_046381475.1 2170883..2172085(-) (htrA) [Bacillus subtilis strain SRCM102750]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCAAG
CCTGATTGGTGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACGGGCG
CTTTAGATCAGCAGCGGAACAATAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGATCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTCGATGT
CATCACGGAATTTGACGGTTACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(200-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378