Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   TTH_RS04110 Genome accession   NC_006461
Coordinates   759366..760586 (+) Length   406 a.a.
NCBI ID   WP_011228203.1    Uniprot ID   Q5SK58
Organism   Thermus thermophilus HB8     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 754366..765586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TTH_RS04080 (TTHA0788) holA 754477..755355 (-) 879 WP_011228200.1 DNA polymerase III subunit delta -
  TTH_RS04085 (TTHA0789) - 755390..756547 (-) 1158 WP_011228201.1 acyl-CoA dehydrogenase family protein -
  TTH_RS04090 (TTHA0790) - 756557..757183 (-) 627 WP_011228202.1 GNAT family N-acetyltransferase -
  TTH_RS04095 (TTHA0791) - 757217..758299 (+) 1083 WP_011172884.1 PIG-L deacetylase family protein -
  TTH_RS04100 (TTHA0792) scpB 758243..758776 (-) 534 WP_008632201.1 SMC-Scp complex subunit ScpB -
  TTH_RS04105 (TTHA0793) - 758780..759367 (-) 588 WP_011172885.1 L-threonylcarbamoyladenylate synthase -
  TTH_RS04110 (TTHA0794) pilC 759366..760586 (+) 1221 WP_011228203.1 type II secretion system F family protein Machinery gene
  TTH_RS04115 (TTHA0795) - 760561..761013 (-) 453 WP_011228204.1 EVE domain-containing protein -
  TTH_RS04120 (TTHA0796) - 761082..761549 (+) 468 WP_011228205.1 hypothetical protein -
  TTH_RS04125 (TTHA0797) - 761564..762919 (+) 1356 WP_011228206.1 FAD-binding oxidoreductase -
  TTH_RS04130 (TTHA0798) - 762972..763922 (+) 951 WP_011228207.1 GGDEF domain-containing protein -
  TTH_RS04135 (TTHA0799) - 763907..764986 (-) 1080 WP_011228208.1 prephenate dehydrogenase/arogenate dehydrogenase family protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44687.70 Da        Isoelectric Point: 9.7205

>NTDB_id=24008 TTH_RS04110 WP_011228203.1 759366..760586(+) (pilC) [Thermus thermophilus HB8]
MPVYQYKARDRQGRLVEATIEAEDLRTAARLLRDRGLFVAEIKEPGKGLQAEVRIPALERGPGLKDLAIFSRQLATMLGA
GLTLLQALAILERQTENRKFREILKQVRTDVEGGMAFSEALSKHKIFSRLYVNLVRAGETSGGLDLILDRLASFLEKELE
LRGKIRSAMTYPVIVFVFAVGVAYFLLTGIVPQFAQILTDLGSELPLLTRFLIAVSDLLRAATLPLLLLAVALFFAYRWY
YGTPQGRRVIDRLKLRLPVFGNLNRKTAVARFSRTLALLLSSGVNIVEALDITKGTAGNSVVEEIVEAAKLKIQQGDPLN
LTLAQHPFVFPPMVSSMVAIGEETGALDTMLSKVADFYEREVDEAVASLTAAIEPLMIIFLGVIVGMIVAGMFLPLFKII
GTLSVQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=24008 TTH_RS04110 WP_011228203.1 759366..760586(+) (pilC) [Thermus thermophilus HB8]
ATGCCGGTCTACCAGTATAAGGCCCGGGACCGCCAGGGCCGTCTGGTGGAGGCCACCATTGAGGCCGAGGACCTCCGCAC
CGCCGCGAGGCTCCTCCGCGACCGGGGCCTCTTCGTGGCCGAGATCAAGGAGCCGGGGAAGGGCCTGCAGGCGGAGGTCC
GGATCCCCGCCTTGGAGCGGGGGCCGGGCCTGAAGGACCTCGCCATCTTCTCCCGGCAGCTCGCCACCATGCTGGGGGCG
GGCCTCACCCTCCTCCAGGCCCTCGCCATCCTGGAGCGCCAGACGGAAAACCGGAAGTTCCGGGAGATCCTCAAGCAGGT
GCGCACCGACGTGGAGGGGGGGATGGCCTTCTCCGAGGCCCTCTCCAAGCACAAGATCTTCTCCCGCCTCTACGTGAACC
TGGTGCGGGCGGGGGAGACCTCGGGCGGCCTGGACCTCATCCTGGACCGCTTGGCGAGCTTTCTGGAGAAGGAGCTGGAG
CTAAGGGGCAAGATCCGGAGCGCCATGACCTACCCGGTCATCGTCTTCGTCTTCGCCGTGGGCGTGGCCTACTTCCTCCT
CACGGGGATCGTGCCCCAGTTCGCCCAGATCCTCACGGATTTAGGCTCCGAGCTTCCCCTCCTCACCCGCTTCCTCATCG
CCGTCTCCGACCTTCTTAGGGCGGCCACCCTGCCCCTCCTCCTCCTCGCCGTGGCCCTCTTCTTCGCCTACCGCTGGTAT
TACGGCACCCCCCAGGGGCGTAGGGTCATTGACCGCCTTAAGCTCCGCCTCCCCGTCTTCGGCAACCTCAACCGCAAGAC
CGCCGTGGCCCGCTTCTCCCGCACCCTGGCCCTCCTTCTCTCCAGCGGGGTGAACATCGTGGAGGCCCTGGACATCACCA
AGGGGACCGCGGGCAACAGCGTGGTGGAGGAGATCGTGGAGGCCGCCAAGCTGAAGATCCAGCAGGGCGACCCCTTGAAC
CTCACCCTGGCCCAGCACCCCTTCGTCTTCCCGCCCATGGTGAGCTCCATGGTGGCCATCGGCGAGGAGACGGGGGCCCT
GGACACCATGCTCTCCAAGGTGGCCGACTTCTATGAGCGGGAGGTGGACGAGGCGGTGGCGAGCCTCACCGCGGCCATTG
AGCCCCTCATGATCATCTTCCTGGGCGTCATCGTGGGCATGATCGTGGCCGGGATGTTCCTGCCCCTCTTCAAGATCATC
GGGACCCTCTCCGTACAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(272-395)

Type II secretion system (T2SS), protein F (T2SSF)

(70-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 2WHN

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Thermus thermophilus HB27

100

100

1
  pilC Acinetobacter baylyi ADP1

38.462

99.261

0.382
  pilC Pseudomonas stutzeri DSM 10701

36.908

98.768

0.365
  pilC Acinetobacter baumannii D1279779

36.658

98.768

0.362

Multiple sequence alignment