Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   STR_RS01015 Genome accession   NC_006449
Coordinates   174416..175165 (+) Length   249 a.a.
NCBI ID   WP_011226806.1    Uniprot ID   -
Organism   Streptococcus thermophilus CNRZ1066     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 169416..180165
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STR_RS10635 (str0156) - 169991..170161 (+) 171 WP_011225360.1 hypothetical protein -
  STR_RS09635 (str0157) - 170248..170355 (+) 108 WP_011226802.1 LPXTG cell wall anchor domain-containing protein -
  STR_RS01000 (str0158) - 170442..171182 (-) 741 WP_011226803.1 amino acid ABC transporter ATP-binding protein -
  STR_RS01005 (str0159) - 171182..172732 (-) 1551 WP_011225362.1 ABC transporter substrate-binding protein/permease -
  STR_RS01010 (str0160) - 172935..173789 (+) 855 WP_041826950.1 undecaprenyl-diphosphate phosphatase -
  STR_RS09640 (str0161) - 173935..174150 (-) 216 WP_011226805.1 DUF3021 family protein -
  STR_RS01015 (str0162) mecA 174416..175165 (+) 750 WP_011226806.1 adaptor protein MecA Regulator
  STR_RS01020 (str0163) - 175169..176326 (+) 1158 WP_002947632.1 glycosyltransferase family 4 protein -
  STR_RS01025 (str0164) sufC 176487..177257 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  STR_RS01030 (str0165) sufD 177294..178556 (+) 1263 WP_002947640.1 Fe-S cluster assembly protein SufD -
  STR_RS01035 (str0166) - 178610..179842 (+) 1233 WP_011226807.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29170.70 Da        Isoelectric Point: 4.0659

>NTDB_id=23945 STR_RS01015 WP_011226806.1 174416..175165(+) (mecA) [Streptococcus thermophilus CNRZ1066]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVNKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=23945 STR_RS01015 WP_011226806.1 174416..175165(+) (mecA) [Streptococcus thermophilus CNRZ1066]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAATT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGAATAAATCAGATCTT
AAGGAAGCCCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMG 18311

99.598

100

0.996
  mecA Streptococcus thermophilus LMD-9

98.795

100

0.988
  mecA Streptococcus mutans UA159

56.967

97.992

0.558
  mecA Streptococcus pneumoniae Rx1

45.783

100

0.458
  mecA Streptococcus pneumoniae D39

45.783

100

0.458
  mecA Streptococcus pneumoniae R6

45.783

100

0.458
  mecA Streptococcus pneumoniae TIGR4

45.783

100

0.458

Multiple sequence alignment