Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CGZ53_RS01935 Genome accession   NZ_CP022435
Coordinates   358405..359163 (+) Length   252 a.a.
NCBI ID   WP_046392074.1    Uniprot ID   A0A6L6G5N0
Organism   Streptococcus uberis strain NZ01     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 353405..364163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGZ53_RS01920 (CGZ53_01915) - 353728..355278 (-) 1551 WP_012657875.1 ABC transporter substrate-binding protein/permease -
  CGZ53_RS01925 (CGZ53_01920) - 355480..357381 (+) 1902 WP_100911914.1 DUF2207 domain-containing protein -
  CGZ53_RS01930 (CGZ53_01925) - 357451..358290 (+) 840 WP_012657877.1 undecaprenyl-diphosphate phosphatase -
  CGZ53_RS01935 (CGZ53_01930) mecA 358405..359163 (+) 759 WP_046392074.1 adaptor protein MecA Regulator
  CGZ53_RS01940 (CGZ53_01935) - 359170..360327 (+) 1158 WP_100911915.1 glycosyltransferase family 4 protein -
  CGZ53_RS01945 (CGZ53_01940) - 360649..361005 (+) 357 WP_100911916.1 hypothetical protein -
  CGZ53_RS01950 (CGZ53_01945) sufC 361201..361971 (+) 771 WP_012657881.1 Fe-S cluster assembly ATPase SufC -
  CGZ53_RS01955 (CGZ53_01950) sufD 362076..363347 (+) 1272 WP_100911917.1 Fe-S cluster assembly protein SufD -

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 29418.22 Da        Isoelectric Point: 4.1355

>NTDB_id=239369 CGZ53_RS01935 WP_046392074.1 358405..359163(+) (mecA) [Streptococcus uberis strain NZ01]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKEINFDDLADLGDVSQMTPEDFFKTIEKSMIEKGDVNAHEKLEKIEEMMEEAVDAVMTQNAEEQKEEESPFEPLDYVHY
VLDFMTIQDAITFSKTVTFPIEASELYKSSDRYHMTILLDIQNQPSYYANVMYARLIEHALPGSKTRAYLQEHAHQLLED
YAVTELQKVELV

Nucleotide


Download         Length: 759 bp        

>NTDB_id=239369 CGZ53_RS01935 WP_046392074.1 358405..359163(+) (mecA) [Streptococcus uberis strain NZ01]
ATGGAAATGAAACAAATCAGCGAAACAACGCTAAAAATCACTATTAGTATGGATGATCTGGAAGAAAGAGGAATGGAGTT
AAAAGACTTCTTAATCCCTCAAGAAAAAACGGAAGAATTCTTTTACACTGTCATGGATGAGCTAGACTTACCTGATAATT
TTAAAGACAGTGGTATGTTAAGTTTCCGAGTTACTCCAAGAAAGGACCGTTTGGATGTCTTTGTCACCAAATCAGATTTG
AATAAAGAAATTAATTTTGATGATTTGGCAGACTTGGGAGATGTTTCTCAAATGACACCTGAAGACTTCTTCAAAACAAT
TGAGAAGAGTATGATTGAAAAAGGTGATGTTAACGCTCATGAGAAACTAGAGAAAATTGAAGAAATGATGGAAGAAGCAG
TAGATGCTGTTATGACGCAAAATGCTGAAGAGCAAAAGGAAGAAGAATCTCCTTTTGAACCACTAGACTATGTGCACTAC
GTTTTGGATTTCATGACCATTCAAGATGCCATTACCTTTTCTAAAACAGTGACCTTCCCGATAGAAGCTTCTGAATTATA
TAAAAGTTCTGACCGATATCACATGACCATATTATTGGATATTCAAAACCAACCTTCTTATTATGCCAATGTCATGTATG
CTAGATTAATTGAGCATGCACTCCCAGGTAGTAAGACTAGAGCTTACTTGCAGGAACATGCCCATCAATTACTGGAAGAT
TATGCAGTAACAGAATTACAAAAAGTAGAGTTGGTGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6L6G5N0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.855

98.81

0.631
  mecA Streptococcus thermophilus LMD-9

59.274

98.413

0.583
  mecA Streptococcus thermophilus LMG 18311

58.871

98.413

0.579
  mecA Streptococcus pneumoniae Rx1

48.81

100

0.488
  mecA Streptococcus pneumoniae D39

48.81

100

0.488
  mecA Streptococcus pneumoniae R6

48.81

100

0.488
  mecA Streptococcus pneumoniae TIGR4

48.413

100

0.484

Multiple sequence alignment