Detailed information NTG0238990

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: QMA0248_RS04650
• Genome accession: NZ_CP022392
• Coordinates: 951720..952565 (+)
• Length: 281 a.a.
• NCBI ID: WP_003099573.1
• Uniprot ID: A0A1J0MYY1
• Organism: Streptococcus iniae strain QMA0248
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 946720..957565

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMA0248_RS04625 (QMA0248_0934)	-	946842..948164 (+)	1323	WP_225111305.1	PTS sugar transporter subunit IIC	-
QMA0248_RS04630 (QMA0248_0935)	-	948161..949000 (+)	840	WP_003099563.1	alpha/beta hydrolase	-
QMA0248_RS04635 (QMA0248_0936)	ylqF	949470..950324 (+)	855	WP_003099566.1	ribosome biogenesis GTPase YlqF	-
QMA0248_RS04640 (QMA0248_0937)	-	950308..951093 (+)	786	WP_003099568.1	ribonuclease HII	-
QMA0248_RS04645 (QMA0248_0938)	-	951106..951654 (+)	549	WP_003099570.1	sugar O-acetyltransferase	-
QMA0248_RS04650 (QMA0248_0939)	dprA	951720..952565 (+)	846	WP_003099573.1	DNA-processing protein DprA	Machinery gene
QMA0248_RS04655 (QMA0248_0940)	topA	952662..954797 (+)	2136	WP_003099575.1	type I DNA topoisomerase	-
QMA0248_RS04660 (QMA0248_0941)	-	954891..955775 (-)	885	WP_003099578.1	LysR family transcriptional regulator	-
QMA0248_RS04665 (QMA0248_0942)	-	955941..956999 (+)	1059	WP_089180080.1	PTS transporter subunit IIC	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31550.74 Da
• Isoelectric Point: 9.9826

>NTDB_id=238990 QMA0248_RS04650 WP_003099573.1 951720..952565(+) (dprA) [Streptococcus iniae strain QMA0248]
MNNFELYKLKKAGLKNHHILNIIHYSQQTKKSLSLRNMAVVSGTSKPCLFLENYKLLNIKELRVEFKKYPSFSILDKTYP
LALKEIDNPPVLLFYQGNLELLNRHKLAVVGSRKSSAVGNKSVESLIKQLNNQFVIVSGLARGIDTVAHFSSIKQGGETI
AVIGSGLDIYYPKENRRLQEFIAEKHLLLSEYCPKEAPLAHHFPERNRIIAGLSMGVLVAEAKWRSGSLITCRFALDYGR
DIFVVPGAILDKQSQGGNHLIQEGAKLVTKGLDIISEYQFL

Nucleotide

• Length: 846 bp

>NTDB_id=238990 QMA0248_RS04650 WP_003099573.1 951720..952565(+) (dprA) [Streptococcus iniae strain QMA0248]
ATGAATAACTTTGAACTGTATAAATTAAAGAAAGCTGGCCTAAAAAATCATCATATTCTAAATATCATTCATTATAGCCA
GCAAACTAAGAAATCTCTATCACTTAGAAATATGGCTGTTGTTTCAGGAACAAGTAAACCATGTCTGTTTTTAGAAAATT
ACAAGCTGTTAAATATAAAAGAGTTACGAGTAGAATTTAAGAAGTATCCCAGCTTTTCAATTTTAGACAAGACCTATCCC
CTTGCTTTAAAAGAAATTGATAATCCGCCAGTATTATTATTTTATCAAGGAAATTTAGAGCTTTTAAATCGGCATAAATT
AGCAGTGGTAGGGTCAAGGAAATCCTCAGCAGTTGGAAACAAATCTGTTGAATCTCTCATCAAGCAACTTAATAATCAGT
TTGTTATTGTTAGTGGGTTGGCTAGAGGAATTGATACTGTAGCTCATTTTTCGAGCATCAAACAAGGTGGAGAGACTATT
GCTGTTATTGGATCAGGGTTAGACATTTATTATCCTAAGGAAAATAGAAGATTACAGGAGTTTATTGCTGAAAAGCATTT
ATTATTAAGTGAATATTGCCCTAAGGAAGCACCTTTAGCACATCATTTTCCAGAACGAAATCGCATAATTGCAGGCTTAT
CTATGGGAGTTTTAGTGGCAGAAGCCAAATGGCGTTCTGGTAGTCTAATCACTTGTCGCTTTGCACTTGATTACGGTAGG
GATATTTTTGTTGTTCCAGGCGCCATCCTTGACAAACAGTCGCAGGGAGGGAATCACCTCATTCAAGAGGGAGCGAAGCT
TGTTACAAAAGGACTTGACATCATTTCTGAATACCAATTTTTATAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

3D structure

• AlphaFold DB: A0A1J0MYY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.786	99.644	0.665
dprA/cilB/dalA	Streptococcus mitis SK321	57.5	99.644	0.573
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae D39	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae R6	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	56.786	99.644	0.566
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.644	0.544