Detailed information NTG0234812

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: CDO84_RS11845
• Genome accession: NZ_CP021911
• Coordinates: 2368037..2368654 (-)
• Length: 205 a.a.
• NCBI ID: WP_014664669.1
• Uniprot ID: -
• Organism: Bacillus sp. MD-5
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2363037..2373654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CDO84_RS11820 (CDO84_11820)	rpsT	2363338..2363604 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
CDO84_RS11825 (CDO84_11825)	holA	2363619..2364662 (-)	1044	WP_014664666.1	DNA polymerase III subunit delta	-
CDO84_RS21405	-	2364702..2364815 (-)	114	WP_134975484.1	hypothetical protein	-
CDO84_RS11830 (CDO84_11830)	-	2364892..2365026 (+)	135	WP_003229983.1	YqzM family protein	-
CDO84_RS11835 (CDO84_11835)	comEC	2365067..2367397 (-)	2331	WP_040082574.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
CDO84_RS11840 (CDO84_11840)	-	2367401..2367970 (-)	570	WP_014664668.1	ComE operon protein 2	-
CDO84_RS11845 (CDO84_11845)	comEA	2368037..2368654 (-)	618	WP_014664669.1	helix-hairpin-helix domain-containing protein	Machinery gene
CDO84_RS11850 (CDO84_11850)	comER	2368738..2369559 (+)	822	WP_004398597.1	late competence protein ComER	-
CDO84_RS11855 (CDO84_11855)	-	2369625..2370368 (-)	744	WP_014664670.1	class I SAM-dependent methyltransferase	-
CDO84_RS11860 (CDO84_11860)	rsfS	2370365..2370721 (-)	357	WP_014664671.1	ribosome silencing factor	-
CDO84_RS11865 (CDO84_11865)	yqeK	2370739..2371299 (-)	561	WP_014664672.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
CDO84_RS11870 (CDO84_11870)	-	2371289..2371858 (-)	570	WP_014664673.1	nicotinate-nucleotide adenylyltransferase	-
CDO84_RS11875 (CDO84_11875)	yhbY	2371870..2372160 (-)	291	WP_014664674.1	ribosome assembly RNA-binding protein YhbY	-
CDO84_RS11880 (CDO84_11880)	aroE	2372154..2372996 (-)	843	WP_014664675.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21759.57 Da
• Isoelectric Point: 4.9757

>NTDB_id=234812 CDO84_RS11845 WP_014664669.1 2368037..2368654(-) (comEA) [Bacillus sp. MD-5]
MNWLNQHKKAMILAASAAVFTAIMIFLASGRNKEPVKQAVPTETVNTEVKQEAGKDEPSEAIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTNEQADEVQVNLAEILQDGTVVYIPKKGEETAVQQGAGGAVQSGGGKGELVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFHTIEDITKVSGIGEKSFEKIKSSISVK

Nucleotide

• Length: 618 bp

>NTDB_id=234812 CDO84_RS11845 WP_014664669.1 2368037..2368654(-) (comEA) [Bacillus sp. MD-5]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATGATTTTAGCGGCTTCTGCAGCTGTTTTCACAGCAATTATGATCTTTCT
GGCCAGCGGGAGAAACAAAGAGCCGGTGAAGCAGGCTGTACCAACTGAGACGGTAAATACAGAGGTAAAGCAGGAAGCAG
GCAAAGATGAGCCAAGCGAAGCAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGCGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCAGGTGGAACCAATGAGCAAGCTGATGAAGTGCAAGTGAATTTGGCGGA
GATTCTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAAGGAGAGGAAACAGCAGTGCAGCAGGGTGCCGGAGGAGCTG
TTCAAAGCGGTGGAGGGAAGGGGGAGCTGGTAAATATCAATACAGCCACCTTAGAGGAGTTACAAGGCATCTCAGGAGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAAGAAAATGGGCGTTTCCATACTATTGAAGATATCACGAAGGT
TTCAGGAATAGGCGAAAAGTCATTTGAGAAAATAAAGTCTTCCATTTCAGTAAAGTGA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (63-118)

• Helix-hairpin-helix motif (HHH_3) (141-202)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	91.22	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	35.398	100	0.39
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.579	92.683	0.385
comEA/celA/cilE	Streptococcus pneumoniae D39	41.579	92.683	0.385
comEA/celA/cilE	Streptococcus pneumoniae R6	41.579	92.683	0.385