Detailed information NTG0234302

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: BB165_RS10570
• Genome accession: NZ_CP021870
• Coordinates: 2050378..2051607 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728358.1
• Uniprot ID: A0AAW3HT93
• Organism: Streptococcus agalactiae strain SG-M4
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2045378..2056607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BB165_RS10545 (BB165_10545)	-	2046540..2049119 (+)	2580	WP_000154437.1	YfhO family protein	-
BB165_RS10565 (BB165_10565)	rlmH	2049698..2050177 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
BB165_RS10570 (BB165_10570)	htrA	2050378..2051607 (+)	1230	WP_000728358.1	trypsin-like peptidase domain-containing protein	Regulator
BB165_RS10575 (BB165_10575)	spo0J	2051705..2052478 (+)	774	WP_000456087.1	ParB/RepB/Spo0J family partition protein	Regulator
BB165_RS10580 (BB165_10580)	dnaA	2052677..2054038 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
BB165_RS10585 (BB165_10585)	dnaN	2054193..2055329 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
BB165_RS10590 (BB165_10590)	-	2055387..2056280 (+)	894	WP_000987441.1	diacylglycerol kinase family protein	-
BB165_RS10595 (BB165_10595)	-	2056290..2056487 (+)	198	WP_000285199.1	DUF951 family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43118.59 Da
• Isoelectric Point: 9.5271

>NTDB_id=234302 BB165_RS10570 WP_000728358.1 2050378..2051607(+) (htrA) [Streptococcus agalactiae strain SG-M4]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVVSPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=234302 BB165_RS10570 WP_000728358.1 2050378..2051607(+) (htrA) [Streptococcus agalactiae strain SG-M4]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGTATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.104	96.088	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.281	97.311	0.548
htrA	Streptococcus pneumoniae TIGR4	54.791	99.511	0.545
htrA	Streptococcus pneumoniae Rx1	54.791	99.511	0.545
htrA	Streptococcus pneumoniae D39	54.791	99.511	0.545
htrA	Streptococcus pneumoniae R6	54.791	99.511	0.545