Detailed information
Bioinformatically predicted
Overview
| Name | comYB | Type | Machinery gene |
| Locus tag | BB164_RS01045 | Genome accession | NZ_CP021867 |
| Coordinates | 173002..174045 (+) | Length | 347 a.a. |
| NCBI ID | WP_223295889.1 | Uniprot ID | - |
| Organism | Streptococcus agalactiae strain SG-M25 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 174119..214121 | 173002..174045 | flank | 74 |
Gene organization within MGE regions
Location: 173002..214121
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BB164_RS01045 (BB164_01045) | comYB | 173002..174045 (+) | 1044 | WP_223295889.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| BB164_RS01050 (BB164_01050) | - | 174042..174110 (+) | 69 | Protein_150 | competence protein ComGF | - |
| BB164_RS01055 (BB164_01055) | - | 174119..175573 (-) | 1455 | WP_001044789.1 | recombinase family protein | - |
| BB164_RS01060 (BB164_01060) | - | 175731..176069 (-) | 339 | WP_000390807.1 | hypothetical protein | - |
| BB164_RS01065 (BB164_01065) | - | 176073..176501 (-) | 429 | WP_000200806.1 | hypothetical protein | - |
| BB164_RS01070 (BB164_01070) | - | 176513..177097 (-) | 585 | WP_000823130.1 | hypothetical protein | - |
| BB164_RS01075 (BB164_01075) | - | 177100..177297 (-) | 198 | WP_000880827.1 | hypothetical protein | - |
| BB164_RS01080 (BB164_01080) | - | 177316..178056 (-) | 741 | WP_000580170.1 | XRE family transcriptional regulator | - |
| BB164_RS01085 (BB164_01085) | - | 178210..178431 (+) | 222 | WP_000215930.1 | helix-turn-helix transcriptional regulator | - |
| BB164_RS11815 | - | 178686..178835 (+) | 150 | WP_001074679.1 | BOW99_gp33 family protein | - |
| BB164_RS01090 (BB164_01090) | - | 178875..179207 (+) | 333 | WP_000072970.1 | hypothetical protein | - |
| BB164_RS01095 (BB164_01095) | - | 179428..180099 (+) | 672 | WP_000131170.1 | ERF family protein | - |
| BB164_RS01100 (BB164_01100) | - | 180103..181098 (+) | 996 | WP_000159058.1 | DUF1351 domain-containing protein | - |
| BB164_RS01105 (BB164_01105) | - | 181100..181651 (+) | 552 | WP_001010334.1 | MazG-like family protein | - |
| BB164_RS01110 (BB164_01110) | ssbA | 181742..182215 (+) | 474 | WP_000609569.1 | single-stranded DNA-binding protein | Machinery gene |
| BB164_RS01115 (BB164_01115) | - | 182212..182490 (+) | 279 | WP_001082484.1 | hypothetical protein | - |
| BB164_RS01120 (BB164_01120) | - | 182504..183295 (+) | 792 | WP_029667750.1 | DNA methyltransferase | - |
| BB164_RS01125 (BB164_01125) | - | 183282..183485 (+) | 204 | WP_000163592.1 | hypothetical protein | - |
| BB164_RS01130 (BB164_01130) | - | 183482..183895 (+) | 414 | WP_000862186.1 | helix-turn-helix domain-containing protein | - |
| BB164_RS01135 (BB164_01135) | - | 183908..184339 (+) | 432 | WP_000412398.1 | hypothetical protein | - |
| BB164_RS01140 (BB164_01140) | - | 184341..185075 (+) | 735 | WP_001293548.1 | hypothetical protein | - |
| BB164_RS01150 (BB164_01150) | - | 185718..186044 (+) | 327 | WP_000836878.1 | DUF1372 family protein | - |
| BB164_RS01155 (BB164_01155) | - | 186177..186785 (+) | 609 | WP_001019158.1 | DUF1642 domain-containing protein | - |
| BB164_RS01160 (BB164_01160) | - | 186772..187020 (+) | 249 | WP_000958011.1 | hypothetical protein | - |
| BB164_RS01165 (BB164_01165) | - | 187031..187426 (+) | 396 | WP_000667207.1 | hypothetical protein | - |
| BB164_RS01170 (BB164_01170) | - | 187423..187812 (+) | 390 | WP_000614972.1 | YopX family protein | - |
| BB164_RS01180 (BB164_01180) | - | 187982..188362 (+) | 381 | WP_000164677.1 | hypothetical protein | - |
| BB164_RS01185 (BB164_01185) | - | 188405..188605 (+) | 201 | WP_001103600.1 | hypothetical protein | - |
| BB164_RS01190 (BB164_01190) | - | 188628..188843 (+) | 216 | WP_223875938.1 | hypothetical protein | - |
| BB164_RS01195 (BB164_01195) | - | 188929..190008 (+) | 1080 | WP_001038279.1 | DUF4417 domain-containing protein | - |
| BB164_RS01200 (BB164_01200) | - | 189998..190408 (+) | 411 | WP_000509432.1 | hypothetical protein | - |
| BB164_RS01205 (BB164_01205) | - | 190601..191044 (+) | 444 | WP_001136854.1 | hypothetical protein | - |
| BB164_RS01210 (BB164_01210) | - | 191031..192344 (+) | 1314 | WP_001167688.1 | PBSX family phage terminase large subunit | - |
| BB164_RS01215 (BB164_01215) | - | 192356..193939 (+) | 1584 | WP_000052338.1 | phage portal protein | - |
| BB164_RS01220 (BB164_01220) | - | 194038..195207 (+) | 1170 | WP_000140092.1 | phage minor capsid protein | - |
| BB164_RS01225 (BB164_01225) | - | 195343..195921 (+) | 579 | WP_000011256.1 | phage scaffolding protein | - |
| BB164_RS01230 (BB164_01230) | - | 195944..196828 (+) | 885 | WP_000224752.1 | hypothetical protein | - |
| BB164_RS01235 (BB164_01235) | - | 196839..197096 (+) | 258 | WP_001269647.1 | hypothetical protein | - |
| BB164_RS01240 (BB164_01240) | - | 197138..197527 (+) | 390 | WP_000221832.1 | hypothetical protein | - |
| BB164_RS01245 (BB164_01245) | - | 197517..197843 (+) | 327 | WP_000565942.1 | putative minor capsid protein | - |
| BB164_RS01250 (BB164_01250) | - | 197843..198205 (+) | 363 | WP_000077535.1 | minor capsid protein | - |
| BB164_RS01255 (BB164_01255) | - | 198206..198613 (+) | 408 | WP_001180646.1 | minor capsid protein | - |
| BB164_RS01260 (BB164_01260) | - | 198616..199071 (+) | 456 | WP_000251918.1 | phage tail tube protein | - |
| BB164_RS01265 (BB164_01265) | - | 199103..199501 (+) | 399 | WP_000069050.1 | hypothetical protein | - |
| BB164_RS01270 (BB164_01270) | - | 199504..200088 (+) | 585 | WP_000459714.1 | Gp15 family bacteriophage protein | - |
| BB164_RS01275 (BB164_01275) | - | 200107..203883 (+) | 3777 | WP_000763172.1 | tape measure protein | - |
| BB164_RS01280 (BB164_01280) | - | 203876..205324 (+) | 1449 | WP_001293185.1 | distal tail protein Dit | - |
| BB164_RS01285 (BB164_01285) | - | 205324..208125 (+) | 2802 | WP_001882115.1 | phage tail protein | - |
| BB164_RS01290 (BB164_01290) | - | 208136..210148 (+) | 2013 | WP_000536261.1 | DUF859 family phage minor structural protein | - |
| BB164_RS01295 (BB164_01295) | - | 210162..210488 (+) | 327 | WP_000404431.1 | DUF1366 domain-containing protein | - |
| BB164_RS01300 (BB164_01300) | - | 210517..210675 (+) | 159 | WP_418287329.1 | CD1375 family protein | - |
| BB164_RS01305 (BB164_01305) | - | 210688..210990 (+) | 303 | WP_000215499.1 | hypothetical protein | - |
| BB164_RS01310 (BB164_01310) | - | 210992..211327 (+) | 336 | WP_001001960.1 | phage holin | - |
| BB164_RS01315 (BB164_01315) | - | 211329..212048 (+) | 720 | WP_000236381.1 | peptidoglycan amidohydrolase family protein | - |
| BB164_RS01320 (BB164_01320) | comGF | 212261..212683 (+) | 423 | WP_001264244.1 | competence type IV pilus minor pilin ComGF | - |
| BB164_RS01325 (BB164_01325) | comGG | 212661..213032 (+) | 372 | WP_000601104.1 | competence type IV pilus minor pilin ComGG | - |
| BB164_RS01330 (BB164_01330) | comYH | 213147..214121 (+) | 975 | WP_001008574.1 | class I SAM-dependent methyltransferase | Machinery gene |
Sequence
Protein
Download Length: 347 a.a. Molecular weight: 39936.65 Da Isoelectric Point: 9.9002
>NTDB_id=234109 BB164_RS01045 WP_223295889.1 173002..174045(+) (comYB) [Streptococcus agalactiae strain SG-M25]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDSMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRNYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGIELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDSMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRNYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGIELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS
Nucleotide
Download Length: 1044 bp
>NTDB_id=234109 BB164_RS01045 WP_223295889.1 173002..174045(+) (comYB) [Streptococcus agalactiae strain SG-M25]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGTATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGAATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTATTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGCCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCCGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGTATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGAATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTATTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGCCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCCGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYB | Streptococcus mutans UA140 |
62.17 |
98.271 |
0.611 |
| comYB | Streptococcus mutans UA159 |
61.877 |
98.271 |
0.608 |
| comYB | Streptococcus gordonii str. Challis substr. CH1 |
56.305 |
98.271 |
0.553 |
| comGB/cglB | Streptococcus mitis NCTC 12261 |
55.224 |
96.542 |
0.533 |
| comGB/cglB | Streptococcus mitis SK321 |
54.627 |
96.542 |
0.527 |
| comGB/cglB | Streptococcus pneumoniae Rx1 |
53.731 |
96.542 |
0.519 |
| comGB/cglB | Streptococcus pneumoniae D39 |
53.731 |
96.542 |
0.519 |
| comGB/cglB | Streptococcus pneumoniae R6 |
53.731 |
96.542 |
0.519 |
| comGB/cglB | Streptococcus pneumoniae TIGR4 |
53.731 |
96.542 |
0.519 |
| comGB | Lactococcus lactis subsp. cremoris KW2 |
50.148 |
97.118 |
0.487 |