Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CCZ24_RS05185 Genome accession   NZ_CP021773
Coordinates   1019195..1019875 (+) Length   226 a.a.
NCBI ID   WP_071659919.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain B105     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1014195..1024875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCZ24_RS05170 (CCZ24_05090) pstB 1014893..1015651 (+) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -
  CCZ24_RS05175 (CCZ24_05095) phoU 1015685..1016338 (+) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  CCZ24_RS05180 (CCZ24_05100) - 1016484..1019033 (+) 2550 WP_000859382.1 M1 family metallopeptidase -
  CCZ24_RS05185 (CCZ24_05105) ciaR 1019195..1019875 (+) 681 WP_071659919.1 response regulator transcription factor Regulator
  CCZ24_RS05190 (CCZ24_05110) ciaH 1019859..1021172 (+) 1314 WP_000042576.1 HAMP domain-containing sensor histidine kinase Regulator
  CCZ24_RS05195 (CCZ24_05115) - 1021261..1021593 (+) 333 WP_000402075.1 putative DNA-binding protein -
  CCZ24_RS05200 (CCZ24_05120) ffh 1021611..1023176 (+) 1566 WP_000863591.1 signal recognition particle protein -
  CCZ24_RS05205 (CCZ24_05125) - 1023243..1023929 (+) 687 WP_000280311.1 SatD family protein -
  CCZ24_RS05210 (CCZ24_05130) - 1023919..1024692 (+) 774 WP_000622399.1 DUF3307 domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25851.64 Da        Isoelectric Point: 4.2854

>NTDB_id=233341 CCZ24_RS05185 WP_071659919.1 1019195..1019875(+) (ciaR) [Streptococcus agalactiae strain B105]
MIKILLIEDDLSLSNSVFDFLDDFADVMQIFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KESIDDKGQGFDLGADDYLTKPFYLEELKMRIQALLKRSGKFNDNSLIYGDIRVDMSTNSTFVNQTEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSNTTISVVEVYVSKVRKKLKGTLFSENLQTLRSVGYILKHVETD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=233341 CCZ24_RS05185 WP_071659919.1 1019195..1019875(+) (ciaR) [Streptococcus agalactiae strain B105]
ATGATAAAAATTTTATTAATTGAAGATGACTTGAGTCTTTCCAATTCCGTTTTTGATTTCCTTGATGACTTTGCCGATGT
CATGCAAATTTTTGATGGAGAAGAGGGTCTTTACGAAGCCGAAAGTGGAGTCTATGATCTGATTCTTCTAGATCTCATGT
TACCTGAAAAAAACGGCTTCCAAGTGTTGAAAGAGCTACGTGAAAAAGGTATTACAACCCCTGTATTAATAATGACCGCT
AAAGAAAGCATTGATGATAAGGGACAAGGTTTCGACTTAGGTGCTGATGATTATCTAACAAAACCTTTTTACCTAGAAGA
ACTAAAAATGCGAATTCAGGCTCTTTTAAAGCGTTCTGGAAAATTTAATGATAACAGCCTAATTTATGGTGATATTCGCG
TAGACATGTCTACTAACTCAACCTTTGTTAATCAAACAGAAGTTGAGCTCTTAGGTAAAGAGTTTGATCTTTTAGTCTAT
TTCCTTCAAAATCAAAATGTTATCTTACCGAAATCTCAAATCTTTGATCGTATTTGGGGATTTGATAGTAATACAACGAT
TTCAGTTGTAGAAGTCTATGTCTCTAAGGTTCGGAAAAAATTAAAAGGAACACTTTTTTCAGAAAACCTTCAAACTTTGC
GTAGTGTAGGATATATTTTAAAGCATGTCGAAACCGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

87.946

99.115

0.872
  ciaR Streptococcus pneumoniae D39

87.946

99.115

0.872
  ciaR Streptococcus pneumoniae R6

87.946

99.115

0.872
  ciaR Streptococcus pneumoniae Rx1

87.946

99.115

0.872
  ciaR Streptococcus mutans UA159

88.235

97.788

0.863
  vicR Streptococcus mutans UA159

35.193

100

0.363
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.607

99.115

0.363

Multiple sequence alignment