Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | LJ_RS03175 | Genome accession | NC_005362 |
| Coordinates | 670866..673025 (+) | Length | 719 a.a. |
| NCBI ID | WP_011161716.1 | Uniprot ID | Q74KH8 |
| Organism | Lactobacillus johnsonii NCC 533 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 661355..688430 | 670866..673025 | within | 0 |
| IS/Tn | 669262..670311 | 670866..673025 | flank | 555 |
Gene organization within MGE regions
Location: 661355..688430
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LJ_RS03120 (LJ0763b) | - | 661355..661507 (+) | 153 | WP_004896917.1 | hypothetical protein | - |
| LJ_RS03125 (LJ0764) | - | 661510..662817 (+) | 1308 | WP_011161706.1 | sensor histidine kinase | - |
| LJ_RS03130 (LJ0765) | - | 662960..664117 (+) | 1158 | WP_011161707.1 | RNA-guided endonuclease InsQ/TnpB family protein | - |
| LJ_RS03135 (LJ0766) | - | 664315..665112 (+) | 798 | WP_011161708.1 | LytR/AlgR family response regulator transcription factor | - |
| LJ_RS03140 (LJ0767) | comA | 665125..667284 (+) | 2160 | WP_011161709.1 | peptide cleavage/export ABC transporter | Regulator |
| LJ_RS03145 (LJ0768) | - | 667295..667888 (+) | 594 | WP_011161710.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| LJ_RS03150 (LJ0769) | - | 668015..668242 (+) | 228 | WP_011161711.1 | bacteriocin class II family protein | - |
| LJ_RS03155 (LJ0769b) | - | 668253..668441 (+) | 189 | WP_011161712.1 | Blp family class II bacteriocin | - |
| LJ_RS03160 (LJ0770) | - | 668528..668902 (+) | 375 | WP_011161713.1 | hypothetical protein | - |
| LJ_RS03165 (LJ0772) | - | 669262..670311 (+) | 1050 | WP_011161461.1 | IS30-like element ISLjo1 family transposase | - |
| LJ_RS03170 (LJ0773) | - | 670449..670853 (+) | 405 | WP_250697983.1 | LytTR family DNA-binding domain-containing protein | - |
| LJ_RS03175 (LJ0774) | comA | 670866..673025 (+) | 2160 | WP_011161716.1 | peptide cleavage/export ABC transporter | Regulator |
| LJ_RS03180 (LJ0775) | - | 673036..673629 (+) | 594 | WP_011161717.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| LJ_RS03185 (LJ0775b) | - | 673779..673973 (+) | 195 | WP_011161718.1 | hypothetical protein | - |
| LJ_RS03190 (LJ0776) | - | 674086..674376 (+) | 291 | WP_011161719.1 | bacteriocin immunity protein | - |
| LJ_RS03195 (LJ0777) | - | 674461..675693 (+) | 1233 | WP_011161720.1 | CPBP family intramembrane glutamic endopeptidase | - |
| LJ_RS03200 (LJ0778) | - | 675789..676064 (+) | 276 | WP_135014112.1 | hypothetical protein | - |
| LJ_RS03210 (LJ0780) | - | 676269..676499 (+) | 231 | WP_004896932.1 | hypothetical protein | - |
| LJ_RS03215 (LJ0781) | - | 676622..676936 (+) | 315 | WP_004896933.1 | bacteriocin immunity protein | - |
| LJ_RS03220 (LJ0782) | - | 676939..677223 (+) | 285 | WP_004896934.1 | hypothetical protein | - |
| LJ_RS03225 | - | 677287..680119 (+) | 2833 | Protein_633 | cation-transporting P-type ATPase | - |
| LJ_RS03230 (LJ0785) | - | 680190..681038 (+) | 849 | WP_011161725.1 | patatin-like phospholipase family protein | - |
| LJ_RS03235 (LJ0786) | - | 681139..682632 (+) | 1494 | WP_011161726.1 | ABC transporter substrate-binding protein/permease | - |
| LJ_RS03240 (LJ0787) | - | 682619..683350 (+) | 732 | WP_011161727.1 | amino acid ABC transporter ATP-binding protein | - |
| LJ_RS03245 (LJ0788) | - | 683446..683967 (+) | 522 | WP_004896939.1 | GNAT family N-acetyltransferase | - |
| LJ_RS03250 (LJ0789) | - | 684085..684954 (+) | 870 | WP_004896940.1 | phosphate ABC transporter substrate-binding protein | - |
| LJ_RS03255 (LJ0790) | pstC | 684971..685963 (+) | 993 | WP_011161729.1 | phosphate ABC transporter permease subunit PstC | - |
| LJ_RS03260 (LJ0791) | pstA | 685963..686853 (+) | 891 | WP_011161730.1 | phosphate ABC transporter permease PstA | - |
| LJ_RS03265 (LJ0792) | pstB | 686864..687664 (+) | 801 | WP_004896943.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| LJ_RS03270 (LJ0793) | pstB | 687675..688430 (+) | 756 | WP_011161731.1 | phosphate ABC transporter ATP-binding protein PstB | - |
Sequence
Protein
Download Length: 719 a.a. Molecular weight: 81091.26 Da Isoelectric Point: 6.5844
>NTDB_id=23181 LJ_RS03175 WP_011161716.1 670866..673025(+) (comA) [Lactobacillus johnsonii NCC 533]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYQSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFNEDT
IQYPFIVHVLKQGELLHYYVVLKNTKNYLVIADPDPSVGIIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGLVLAAQNTTLFGITLLALPVYA
IVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKTESLQTALKTFIQ
LSLNVIILWVGARVVMQGEMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LEGMIEYKHVDYRYGYGTDVLKDINLKIKPDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRADISEEEVIKACQIAGIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDKGQIVEEGSHEELMEQHGFYYDLVKG
MLFKYKSVYVPQVDEMDCGVACLAMILKQYQSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFNEDT
IQYPFIVHVLKQGELLHYYVVLKNTKNYLVIADPDPSVGIIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGLVLAAQNTTLFGITLLALPVYA
IVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKTESLQTALKTFIQ
LSLNVIILWVGARVVMQGEMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LEGMIEYKHVDYRYGYGTDVLKDINLKIKPDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRADISEEEVIKACQIAGIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDKGQIVEEGSHEELMEQHGFYYDLVKG
Nucleotide
Download Length: 2160 bp
>NTDB_id=23181 LJ_RS03175 WP_011161716.1 670866..673025(+) (comA) [Lactobacillus johnsonii NCC 533]
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTCTAGCAATGATCTT
AAAGCAGTATCAATCTCGTGTGTCTTTAGCACATTTGCGTCACGAAGCTCGCACAAATCTTGAAGGCACAACTGCGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATACT
ATTCAATACCCTTTTATCGTGCATGTTCTTAAGCAAGGAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGAA
TTACTTAGTAATTGCCGATCCTGATCCATCAGTTGGCATAATAAAGATGCCTAAAGATAAATTTGCTCAAGAATGGACTG
GTATTGCGCTTTTTATGGTTCCGAATGAAGATTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGACTAGTGTTAGCTGCTCAAAATACAACATTATTTGGGATCACATTATTAGCTTTACCAGTGTATGCG
ATAGTAATTCTAGGATTTACTAAGAAATTTGAAAAATTAAATGATGAACAGATGGAGAGTAATGCAGTACTAAGTTCTTC
AGTTATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGCAGAATCGATAGTC
AATTTGTAAACTATTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTGCAGACGGCCTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGAGCAAGAGTAGTGATGCAAGGAGAGATGAGTATTGGTCAATTAATGAC
TTTTAATGCATTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGGCTTCAATCTGCGAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAGGAATGATTGAATACAAGCATGTTGATTATCGATATGGTTATGGTACTGATGTTTTAAAAGATATTAATCTAAA
AATTAAGCCAGATGAAAAATTAGCAATTGTTGGGATGAGTGGATCAGGAAAATCGACGATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCGTAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGGAGAATTTATTACTGGGATGTAGAGCTGATAT
TAGCGAAGAAGAGGTAATTAAAGCCTGTCAGATTGCTGGCATTGATCAGGAGATAGCTAATTTGCCCCTACAATTTGAGA
CAAAGTTAGATGAGAATGCGAAGATTTTATCAGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTTTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGTTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCGGAACGTGCAGATAAGGTCGTTGTAATTGACA
AGGGGCAGATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTCTAGCAATGATCTT
AAAGCAGTATCAATCTCGTGTGTCTTTAGCACATTTGCGTCACGAAGCTCGCACAAATCTTGAAGGCACAACTGCGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATACT
ATTCAATACCCTTTTATCGTGCATGTTCTTAAGCAAGGAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGAA
TTACTTAGTAATTGCCGATCCTGATCCATCAGTTGGCATAATAAAGATGCCTAAAGATAAATTTGCTCAAGAATGGACTG
GTATTGCGCTTTTTATGGTTCCGAATGAAGATTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGACTAGTGTTAGCTGCTCAAAATACAACATTATTTGGGATCACATTATTAGCTTTACCAGTGTATGCG
ATAGTAATTCTAGGATTTACTAAGAAATTTGAAAAATTAAATGATGAACAGATGGAGAGTAATGCAGTACTAAGTTCTTC
AGTTATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGCAGAATCGATAGTC
AATTTGTAAACTATTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTGCAGACGGCCTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGAGCAAGAGTAGTGATGCAAGGAGAGATGAGTATTGGTCAATTAATGAC
TTTTAATGCATTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGGCTTCAATCTGCGAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAGGAATGATTGAATACAAGCATGTTGATTATCGATATGGTTATGGTACTGATGTTTTAAAAGATATTAATCTAAA
AATTAAGCCAGATGAAAAATTAGCAATTGTTGGGATGAGTGGATCAGGAAAATCGACGATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCGTAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGGAGAATTTATTACTGGGATGTAGAGCTGATAT
TAGCGAAGAAGAGGTAATTAAAGCCTGTCAGATTGCTGGCATTGATCAGGAGATAGCTAATTTGCCCCTACAATTTGAGA
CAAAGTTAGATGAGAATGCGAAGATTTTATCAGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTTTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGTTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCGGAACGTGCAGATAAGGTCGTTGTAATTGACA
AGGGGCAGATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus mitis NCTC 12261 |
56.601 |
99.026 |
0.56 |
| comA | Streptococcus mitis SK321 |
56.32 |
99.026 |
0.558 |
| comA | Streptococcus pneumoniae Rx1 |
56.18 |
99.026 |
0.556 |
| comA | Streptococcus pneumoniae D39 |
56.18 |
99.026 |
0.556 |
| comA | Streptococcus pneumoniae R6 |
56.18 |
99.026 |
0.556 |
| comA | Streptococcus pneumoniae TIGR4 |
56.039 |
99.026 |
0.555 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
54.916 |
99.026 |
0.544 |
| comA/nlmT | Streptococcus mutans UA159 |
53.324 |
98.331 |
0.524 |