Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   CCE30_RS01730 Genome accession   NZ_CP021427
Coordinates   330134..332293 (-) Length   719 a.a.
NCBI ID   WP_003649216.1    Uniprot ID   A0AB33C8C0
Organism   Lactobacillus gasseri strain 4M13     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 326261..329396 330134..332293 flank 738


Gene organization within MGE regions


Location: 326261..332293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCE30_RS01695 (CCE30_01695) - 326261..327310 (+) 1050 WP_024273054.1 IS30-like element ISLga1 family transposase -
  CCE30_RS01705 (CCE30_01705) - 327593..327790 (-) 198 WP_003649213.1 Blp family class II bacteriocin -
  CCE30_RS01710 (CCE30_01710) - 327800..328027 (-) 228 WP_049159833.1 Blp family class II bacteriocin -
  CCE30_RS01720 (CCE30_01715) - 328347..329396 (-) 1050 WP_087261269.1 IS30-like element ISLga1 family transposase -
  CCE30_RS01725 (CCE30_01720) - 329530..330123 (-) 594 WP_003649215.1 HlyD family efflux transporter periplasmic adaptor subunit -
  CCE30_RS01730 (CCE30_01725) comA 330134..332293 (-) 2160 WP_003649216.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 719 a.a.        Molecular weight: 81069.37 Da        Isoelectric Point: 7.7712

>NTDB_id=230630 CCE30_RS01730 WP_003649216.1 330134..332293(-) (comA) [Lactobacillus gasseri strain 4M13]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFDENS
IQYPFIAHVLKQGELLHYYVVLKNAKNYLVIADPDPSVGVVKMPKDKFAQEWTGVALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSIFSYGQNFLLNILGQRLSI
DLNLRYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPIYA
VVILGFTKKFEKLNNEQMESNAVLSSSVIEDIQGIETIKALNSENTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFIQ
LSLNVIVLWVGAKIVMQGQLSIGQLMTFNALLAYFIDPLQSIINLQPRLQSASVAQNRLNEVYQVKSEFNQKATIEDRKL
LEGNIEYKNVDYSYGYGTDVLKDINLKISQGEKLTIVGMSGSGKSTMVKLLVDFFSPSKGQVTLNGHATSEIDKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRPDITEEDVIKACQIAEIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKKVIDNLMKLKDKTIIFIAHRLAIAERADKVVVIDHGQIVEEGSHSELMSKHGFYYDLVKG

Nucleotide


Download         Length: 2160 bp        

>NTDB_id=230630 CCE30_RS01730 WP_003649216.1 330134..332293(-) (comA) [Lactobacillus gasseri strain 4M13]
ATGTTATTCAAATATAAATCCGTATACGTGCCACAAGTGGATGAGATGGATTGCGGCGTTGCTTGTCTAGCAATGATCTT
AAAGCAATATCATTCTCGCGTATCTTTAGCACATTTACGTCATGAAGCTCGTACTAATCTTGAAGGCACAACTGCTTTAG
GACTAGTGAAGACAGCACAAAAATTTAATTTCAAAACAGAAGCCGTAAAAGCAGATATGTCTTTATTTGATGAGAATAGT
ATTCAATATCCTTTTATTGCCCACGTCCTAAAACAAGGAGAACTACTTCATTATTACGTAGTTCTTAAAAATGCTAAGAA
TTATTTAGTAATTGCAGATCCTGATCCATCAGTTGGTGTAGTAAAGATGCCAAAAGACAAATTTGCTCAAGAATGGACTG
GTGTTGCACTCTTTATGGTTCCTAACGAAGACTTTGAACCAATCAAAGAAAAGAAGAATAATTTATGGTCTCTCTTTCCA
TATATGTTTAAACAAAAGCGGCTGATGATTAACATCATTTTAGCCGCTTTATTAATGACCATAATTAGTATCTGTAGTTC
ATATTTTGTTCAAGGAATAATTGATACTTACATTCCAGATGGAACCTATCAGACTCTTTCGATCTTAGCTGTTGGACTAT
TAATTGCTTATGTCTTTAATTCAATTTTTTCTTATGGACAGAATTTTTTATTAAATATTTTAGGTCAAAGATTAAGTATT
GATCTAAATCTGCGATACATCAGGCATATTTTTGAATTACCAATGGAATTCTTTGTAACAAGAAGAACGGGTGAAATTAC
TTCGCGTTTTTCTGATGCAAGTAGAATTATTGACGCTTTGGCAAGTACAGTTATTTCGCTCTTCTTAGACCTCTCAATTG
TGATTGTGATGGGATTAGTCTTAGCAGCACAAAATATGACATTATTTGGGATTACACTGTTAGCTTTGCCTATTTATGCA
GTTGTAATTCTAGGTTTTACTAAAAAGTTTGAAAAACTAAATAACGAACAAATGGAAAGTAATGCTGTTTTGAGTTCTTC
AGTTATTGAAGATATTCAAGGAATTGAAACTATTAAAGCTTTAAATAGTGAGAATACAAGATATAGAAGAATCGACAGTC
AGTTTGTAGATTACTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTACAGACAGCACTCAAGACATTTATTCAA
TTATCTCTTAATGTAATTGTTCTTTGGGTTGGTGCAAAGATTGTAATGCAAGGACAATTGAGCATTGGTCAGTTAATGAC
GTTCAATGCATTGCTGGCATATTTCATTGATCCCTTGCAAAGTATTATTAATTTACAACCGCGACTTCAATCAGCTAGTG
TTGCTCAAAATCGATTAAATGAGGTCTATCAAGTAAAAAGTGAATTCAATCAGAAGGCTACTATTGAAGATCGTAAGCTC
CTAGAAGGAAATATTGAATATAAGAATGTGGATTATAGCTATGGTTATGGCACAGATGTCTTAAAAGATATTAATCTCAA
AATTAGCCAGGGCGAAAAATTAACGATTGTTGGAATGAGTGGTTCTGGAAAATCTACGATGGTTAAGTTGTTAGTAGATT
TCTTTTCGCCAAGTAAAGGTCAGGTTACATTAAATGGACATGCAACAAGTGAGATTGATAAGCATACGTTGCGGTCATAT
GTAAATTATGTACCTCAAACTCCATATATCTTTTCTGGAACAGTTAAAGAGAATTTGTTGTTAGGTTGTAGGCCAGATAT
CACTGAAGAAGATGTAATAAAGGCTTGTCAAATTGCTGAGATTGACCAAGAAATAGCTAATCTACCTTTGCAATTTGAAA
CAAAATTAGATGAAAATGCCAAAATTTTATCTGGTGGACAAAAACAAAGGTTAACTATTGCCCGGGCATTACTATCTCCT
GCAAAGGTATTTATTTTTGATGAAGTAACAAGTGGCTTAGATACAATTACTGAGAAGAAAGTGATTGATAATTTGATGAA
GCTAAAGGATAAGACAATTATCTTTATTGCGCATCGACTAGCAATTGCAGAACGGGCAGACAAGGTAGTTGTAATTGATC
ATGGTCAAATAGTTGAAGAAGGCAGCCACAGCGAATTGATGAGTAAGCATGGTTTTTACTATGACTTAGTGAAGGGATAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(501-651)

Peptidase C39 family (Peptidase_C39)

(7-143)

ABC transporter transmembrane region (ABC_membrane)

(169-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

57.725

99.026

0.572
  comA Streptococcus mitis SK321

57.444

99.026

0.569
  comA Streptococcus pneumoniae Rx1

57.303

99.026

0.567
  comA Streptococcus pneumoniae D39

57.303

99.026

0.567
  comA Streptococcus pneumoniae R6

57.303

99.026

0.567
  comA Streptococcus pneumoniae TIGR4

57.163

99.026

0.566
  comA Streptococcus gordonii str. Challis substr. CH1

55.478

99.026

0.549
  comA/nlmT Streptococcus mutans UA159

53.748

98.331

0.529

Multiple sequence alignment