Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SMU_RS08605 Genome accession   NC_004350
Coordinates   1773449..1775740 (-) Length   763 a.a.
NCBI ID   WP_002263352.1    Uniprot ID   Q8DSC1
Organism   Streptococcus mutans UA159     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1768449..1780740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMU_RS08585 (SMU.1876) - 1768984..1769454 (+) 471 WP_002263356.1 hypothetical protein -
  SMU_RS08590 (SMU.1877) - 1770331..1771323 (+) 993 WP_002263355.1 PTS sugar transporter subunit IIB -
  SMU_RS08595 (SMU.1878) - 1771358..1772176 (+) 819 WP_002263354.1 PTS mannose/fructose/sorbose transporter subunit IIC -
  SMU_RS08600 (SMU.1879) - 1772191..1773117 (+) 927 WP_002263353.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
  SMU_RS08605 (SMU.1881c) comA/nlmT 1773449..1775740 (-) 2292 WP_002263352.1 peptide cleavage/export ABC transporter Regulator
  SMU_RS08610 (SMU.1882c) - 1776290..1776643 (-) 354 WP_002263351.1 hypothetical protein -
  SMU_RS08615 (SMU.1883) - 1776962..1777330 (+) 369 WP_002263350.1 DUF956 family protein -
  SMU_RS08620 (SMU.1884c) - 1777567..1778640 (-) 1074 WP_002263349.1 acyltransferase -
  SMU_RS08625 (SMU.1886) serS 1779164..1780444 (+) 1281 WP_002263348.1 serine--tRNA ligase -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 86450.75 Da        Isoelectric Point: 7.1052

>NTDB_id=22999 SMU_RS08605 WP_002263352.1 1773449..1775740(-) (comA/nlmT) [Streptococcus mutans UA159]
MNIFSYLLLTVVSVLLVNLFLEFIKYFFKTTPAMNKENSKKSSIFLWSRTRRFKFVPQVDNRDCGPAALASIAKHYGSYY
SLVHLRELTKTDRQGTTALGIIEAAKNIGFETYSLDADMSLFNYDDLIYPFIVHVVKNKRLQHYYVVYDDEGDSLIIGDP
DPSVKVIRMSKERFQHEWTGVAIFFSPKDDYQPQKDKRRGLTSFIPSFLKQKSLLFYIIMASLIITLIEIIGAFYLQVML
DEYIPSQKISTLGFITLGLIITYVAQQIIAFAKEYLLIILGQRLVIDVILTYIKHIFILPMSFFSTRRTGEITSRFTDAN
QIIDAVASTIFSIFLDISMVFIVGGVLLIQNVVLFFLALLCVPIYIIIVFAFMKMFGYLNYEVMESNAIMSSSVIEDING
IETIKSLTSEEVSYQRIDKEFVDFLEKSFRLHKYGAIQVSIKTAAKLILNIVILWYGARLVMTGKISVGQMIAFNVLLGY
FSSPIENMINLQIKLQSARIANTRLNEVYLVDSEFENNGELSEGSFLDGDISFEKLSYKYGYGRDTLSDINLTIKKGSKV
SLVGASGSGKTTLAKMIVNFYEPIQGLIRLNGYDLKDIDKTVLRQHINYLPQQAYVFSGTIMDNLTLGAKEDTIQEDIIR
ACEIAEIHSDIEQMPLGYQTELSDSTGVSGGQKQRIALARALLTQAPVLILDEATSSLDVLTEKKIVNNLMAMTNKTIVF
VAHRLSIAQRTDRIIVMDQGKIVEEGSHKELLAHKGFYYKLFN

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=22999 SMU_RS08605 WP_002263352.1 1773449..1775740(-) (comA/nlmT) [Streptococcus mutans UA159]
ATGAACATATTTTCTTATCTTCTTTTGACTGTAGTTTCAGTATTATTAGTCAATTTATTCTTAGAATTTATAAAATACTT
TTTTAAAACAACTCCAGCAATGAATAAGGAAAATTCTAAGAAATCTTCAATTTTTTTGTGGAGTCGAACTAGACGTTTTA
AATTTGTACCACAAGTCGATAATAGAGACTGTGGCCCGGCTGCTCTAGCCTCTATTGCCAAACATTATGGTTCATATTAT
TCCTTGGTTCATCTGCGTGAACTTACAAAGACAGATCGACAAGGCACCACAGCATTAGGCATCATTGAAGCTGCCAAAAA
TATTGGATTTGAAACTTACTCGCTAGATGCTGATATGTCTTTATTTAATTATGATGACCTTATTTACCCTTTTATTGTTC
ACGTTGTTAAAAATAAACGTCTTCAACATTACTATGTTGTTTATGACGATGAAGGAGATAGTCTAATCATCGGAGATCCA
GATCCTTCTGTCAAAGTTATTCGCATGTCTAAGGAGAGATTTCAGCATGAATGGACAGGTGTAGCTATCTTCTTTTCCCC
AAAGGATGATTATCAGCCTCAAAAAGATAAAAGAAGAGGATTAACAAGTTTCATACCTTCTTTTTTAAAGCAAAAGAGTC
TCTTGTTCTATATTATAATGGCGAGTTTAATCATTACTTTAATAGAAATTATTGGAGCTTTTTATCTCCAAGTAATGCTG
GATGAGTATATTCCCAGTCAAAAAATTTCAACTTTAGGCTTTATCACTTTAGGATTAATAATAACTTATGTTGCCCAACA
AATAATAGCTTTTGCAAAAGAGTACTTATTAATTATATTAGGACAAAGGCTGGTAATTGATGTTATACTTACTTATATTA
AGCACATTTTTATTCTTCCGATGTCTTTTTTTTCGACAAGACGAACGGGAGAAATCACATCTCGCTTCACTGATGCCAAT
CAAATTATTGATGCTGTGGCGTCAACAATTTTTTCTATTTTCTTAGACATTTCGATGGTATTTATAGTTGGTGGAGTATT
ATTAATTCAAAATGTCGTTTTATTTTTCCTAGCCTTGCTCTGCGTTCCTATCTACATTATCATTGTTTTTGCATTTATGA
AAATGTTTGGTTACTTAAACTATGAGGTAATGGAAAGTAATGCGATAATGTCTTCATCTGTTATTGAGGATATTAATGGA
ATAGAAACTATCAAATCTTTGACGAGTGAAGAAGTTAGCTATCAGAGAATTGACAAGGAATTTGTTGATTTTTTAGAGAA
ATCTTTTAGGCTGCATAAGTATGGAGCTATTCAAGTCTCAATTAAAACTGCTGCAAAGCTAATTTTGAATATCGTTATTC
TATGGTATGGAGCACGATTGGTTATGACCGGGAAAATTTCAGTGGGTCAAATGATTGCTTTTAATGTGCTTTTAGGATAT
TTTTCAAGCCCAATTGAAAATATGATTAATTTACAAATTAAGCTCCAATCAGCCCGCATAGCTAATACGCGTCTCAATGA
AGTCTATCTGGTCGATTCTGAGTTTGAAAATAATGGGGAGCTTTCAGAAGGCAGCTTTTTGGATGGGGATATCTCTTTTG
AAAAGTTATCTTACAAGTATGGTTATGGTCGTGATACTCTGTCAGATATCAATCTAACTATTAAAAAAGGTTCAAAGGTC
AGTCTGGTCGGAGCCTCTGGTTCTGGTAAAACGACTCTTGCCAAGATGATTGTCAATTTTTATGAACCTATACAGGGTCT
TATCCGTCTTAATGGCTATGACCTAAAAGATATAGATAAGACTGTTTTACGCCAGCATATTAACTATCTCCCCCAACAAG
CTTATGTCTTTAGTGGTACCATTATGGATAATCTGACCTTGGGAGCCAAGGAAGACACTATTCAGGAAGATATTATTCGA
GCCTGTGAAATTGCTGAGATTCATTCAGACATTGAACAAATGCCGCTGGGGTACCAGACTGAGTTATCTGATAGTACTGG
AGTTTCCGGTGGCCAGAAGCAGCGGATTGCCTTGGCTCGCGCTCTCTTAACCCAAGCTCCAGTTTTGATTTTGGATGAAG
CCACCAGCAGTCTGGATGTCCTGACTGAAAAGAAAATCGTCAACAACCTCATGGCCATGACCAATAAGACTATTGTTTTT
GTGGCACACCGTTTGAGTATTGCTCAACGGACAGACCGAATTATTGTTATGGATCAAGGTAAGATTGTGGAAGAAGGTAG
CCATAAGGAACTTTTAGCTCATAAAGGCTTCTACTACAAGCTGTTTAACTAA

Domains

Predicted by InterProScan.

ABC transporter transmembrane region (ABC_membrane)

(215-484)

Peptidase C39 family (Peptidase_C39)

(53-189)

ABC transporter (ABC_tran)

(547-696)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DSC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.81

99.083

0.731
  comA Streptococcus mitis NCTC 12261

62.676

93.054

0.583
  comA Streptococcus pneumoniae Rx1

61.831

93.054

0.575
  comA Streptococcus pneumoniae D39

61.831

93.054

0.575
  comA Streptococcus pneumoniae R6

61.831

93.054

0.575
  comA Streptococcus mitis SK321

61.831

93.054

0.575
  comA Streptococcus pneumoniae TIGR4

61.549

93.054

0.573
  comA Streptococcus gordonii str. Challis substr. CH1

60.224

93.578

0.564