Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   B9H01_RS06565 Genome accession   NZ_CP020863
Coordinates   1302001..1302705 (-) Length   234 a.a.
NCBI ID   WP_012775218.1    Uniprot ID   -
Organism   Streptococcus suis strain SC19     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1297001..1307705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B9H01_RS06545 (B9H01_06545) - 1297876..1298625 (-) 750 WP_162286913.1 ATP-binding cassette domain-containing protein -
  B9H01_RS06550 (B9H01_06550) - 1298788..1299330 (-) 543 WP_012027299.1 ATP-binding cassette domain-containing protein -
  B9H01_RS06555 (B9H01_06555) vicX 1299849..1300652 (-) 804 WP_012027300.1 MBL fold metallo-hydrolase Regulator
  B9H01_RS06560 (B9H01_06560) micB 1300659..1302008 (-) 1350 WP_012027301.1 cell wall metabolism sensor histidine kinase VicK Regulator
  B9H01_RS06565 (B9H01_06565) micA 1302001..1302705 (-) 705 WP_012775218.1 response regulator YycF Regulator
  B9H01_RS06570 (B9H01_06570) - 1302899..1303660 (+) 762 WP_012027304.1 amino acid ABC transporter ATP-binding protein -
  B9H01_RS06575 (B9H01_06575) - 1303671..1304510 (+) 840 WP_012027305.1 transporter substrate-binding domain-containing protein -
  B9H01_RS06580 (B9H01_06580) - 1304525..1305223 (+) 699 WP_012028333.1 amino acid ABC transporter permease -
  B9H01_RS06585 (B9H01_06585) - 1305238..1305897 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26807.81 Da        Isoelectric Point: 4.8957

>NTDB_id=226626 B9H01_RS06565 WP_012775218.1 1302001..1302705(-) (micA) [Streptococcus suis strain SC19]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELPETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=226626 B9H01_RS06565 WP_012775218.1 1302001..1302705(-) (micA) [Streptococcus suis strain SC19]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATAGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTACAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGCCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.906

100

0.829
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

37.975

100

0.385

Multiple sequence alignment