Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   C2E46_RS09445 Genome accession   NZ_CP026082
Coordinates   1880912..1881586 (-) Length   224 a.a.
NCBI ID   WP_001238595.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain YZ1605     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1875912..1886586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS09420 (C2E46_09765) dltC 1876528..1876767 (-) 240 WP_000351975.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  C2E46_RS09425 (C2E46_09770) dltB 1876782..1878047 (-) 1266 WP_161501945.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  C2E46_RS09430 (C2E46_09775) dltA 1878044..1879579 (-) 1536 WP_161501946.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  C2E46_RS09435 (C2E46_09780) - 1879592..1879714 (-) 123 WP_000806141.1 teichoic acid D-Ala incorporation-associated protein DltX -
  C2E46_RS09440 (C2E46_09785) dltS 1879725..1880912 (-) 1188 WP_017650156.1 two-component system sensor histidine kinase DltS -
  C2E46_RS09445 (C2E46_09790) ciaR 1880912..1881586 (-) 675 WP_001238595.1 two-component system response regulator DltR Regulator
  C2E46_RS09450 (C2E46_09795) rpmH 1881942..1882076 (-) 135 WP_000831903.1 50S ribosomal protein L34 -
  C2E46_RS09455 (C2E46_09800) - 1882260..1883615 (-) 1356 WP_000712238.1 YjiH family protein -
  C2E46_RS09460 (C2E46_09805) - 1883795..1884970 (-) 1176 WP_000191687.1 IS256-like element ISSag11 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25478.50 Da        Isoelectric Point: 6.0561

>NTDB_id=224533 C2E46_RS09445 WP_001238595.1 1880912..1881586(-) (ciaR) [Streptococcus agalactiae strain YZ1605]
MRLLVVEDEKSIAEAIQALLADKGYSVDLAFDGDDGLEYILTGLYDLVLLDIMLPKRSGLSVLKRVREAGLETPIIFLTA
KSQTYDKVNGLDLGADDYITKPFEADELLARIRLRTRQSSLIRANQLRLGNIRLNTDSHELKSKESSVKLSNKEFLLMEV
FMRNAKQIIPKNQLISKVWGPSDNSEYNQLEVFISFLRKKLRFLKADIEIITTKGFGYSLEEMT

Nucleotide


Download         Length: 675 bp        

>NTDB_id=224533 C2E46_RS09445 WP_001238595.1 1880912..1881586(-) (ciaR) [Streptococcus agalactiae strain YZ1605]
ATGAGACTTCTTGTAGTTGAGGATGAAAAAAGTATAGCAGAGGCTATTCAGGCTTTATTGGCAGATAAAGGTTATTCTGT
TGATTTAGCATTTGATGGAGATGATGGGTTAGAATACATTTTGACAGGTCTCTATGATTTAGTCTTGTTGGATATTATGT
TACCCAAACGCTCAGGATTATCTGTTTTAAAAAGAGTGAGGGAAGCTGGTTTAGAAACCCCAATAATCTTTTTAACTGCA
AAATCACAGACTTATGATAAAGTTAATGGTTTAGATTTAGGGGCAGATGATTATATCACAAAACCCTTTGAAGCAGATGA
ATTGCTAGCTAGAATTAGGCTGAGAACTAGACAATCTTCTCTAATCAGAGCGAATCAATTGCGGCTTGGAAATATAAGGC
TTAACACAGATTCACATGAGCTAAAATCTAAAGAAAGTAGTGTAAAATTATCCAATAAAGAATTTCTCTTGATGGAAGTT
TTTATGCGAAATGCAAAGCAGATTATTCCTAAAAATCAGTTGATTTCTAAGGTTTGGGGACCTTCAGACAATTCAGAATA
TAACCAGTTAGAAGTATTTATTTCTTTTTTGCGAAAAAAATTGCGCTTTTTAAAAGCAGACATTGAAATAATAACCACTA
AGGGCTTTGGATATTCCTTGGAGGAGATGACATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

37.838

99.107

0.375
  ciaR Streptococcus pneumoniae D39

37.668

99.554

0.375
  ciaR Streptococcus pneumoniae R6

37.668

99.554

0.375
  ciaR Streptococcus pneumoniae Rx1

37.668

99.554

0.375
  ciaR Streptococcus pneumoniae TIGR4

37.668

99.554

0.375
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36

100

0.362
  covR Streptococcus salivarius strain HSISS4

35.526

100

0.362