Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   B7D75_RS23420 Genome accession   NZ_CP020560
Coordinates   4942774..4944111 (+) Length   445 a.a.
NCBI ID   WP_033999343.1    Uniprot ID   -
Organism   Pseudomonas paraeruginosa strain Cr1     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4937774..4949111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7D75_RS23395 (B7D75_23410) pgeF 4937919..4938647 (-) 729 WP_043101190.1 peptidoglycan editing factor PgeF -
  B7D75_RS23400 (B7D75_23415) rluD 4938644..4939606 (-) 963 WP_003150035.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  B7D75_RS23405 (B7D75_23420) - 4939752..4940777 (+) 1026 WP_012077305.1 outer membrane protein assembly factor BamD -
  B7D75_RS23410 (B7D75_23425) - 4940931..4941176 (+) 246 WP_003150030.1 PP0621 family protein -
  B7D75_RS23415 (B7D75_23430) pilS 4941166..4942758 (+) 1593 WP_043101193.1 two-component system sensor histidine kinase PilS Regulator
  B7D75_RS23420 (B7D75_23435) pilR 4942774..4944111 (+) 1338 WP_033999343.1 two-component system response regulator PilR Regulator
  B7D75_RS23425 (B7D75_23440) thiO 4944157..4945251 (-) 1095 WP_041025522.1 glycine oxidase ThiO -
  B7D75_RS23430 (B7D75_23445) - 4945386..4945895 (+) 510 WP_003150026.1 GspH/FimT family pseudopilin -
  B7D75_RS23435 (B7D75_23450) - 4946001..4946507 (+) 507 WP_012077308.1 Tfp pilus assembly protein FimT/FimU -
  B7D75_RS23440 (B7D75_23455) pilV 4946498..4947055 (+) 558 WP_053814569.1 type IV pilus modification protein PilV Machinery gene
  B7D75_RS23445 (B7D75_23460) pilW 4947052..4947876 (+) 825 WP_034081447.1 type 4a pilus minor pilin PilW -
  B7D75_RS23450 (B7D75_23465) pilX 4947873..4948460 (+) 588 WP_034081449.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49762.11 Da        Isoelectric Point: 6.1219

>NTDB_id=224133 B7D75_RS23420 WP_033999343.1 4942774..4944111(+) (pilR) [Pseudomonas paraeruginosa strain Cr1]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPTELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MPMQVKLLRAIQEKAVRAVGGQQEIGVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCENDQIQPHDLRLADAPGASQDGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=224133 B7D75_RS23420 WP_033999343.1 4942774..4944111(+) (pilR) [Pseudomonas paraeruginosa strain Cr1]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACCCTCGGCCGCATGAA
GCTGGATACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAACCGTTCGACCTGTGCCTGACCG
ACATGCGCCTGCCGGACGGTAGCGGCCTCGACCTGGTGCAGTACATCCAGCAGCGTCACCCGCAGACCCCGGTCGCCATG
ATCACCGCCTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGCGCCTTCGACTTCCTCACCAAGCCGGTCGA
CCTCGGCCGCCTGCGCGAACTGGTGGCGACCGCCCTGCGCCTGCGCAATCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCGCTGCGCAACCAGATCGGCAAGCTGGCGCGTAGCCAGGCGCCGGTCTAC
ATCAGCGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCCCGCCTGATCCACGAGCAGGGGCCGCGCATCGAGCGACCGTT
CGTGCCGGTCAACTGCGGCGCGATCCCTACCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACCG
GCGCCATCGAGGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGTACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGCCGATGCAGGTCAAGCTGCTCCGCGCAATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGATCGGCGT
CGACGTCCGCATCCTCTGCGCCACTCACAAGGACCTCGCCGCCGAGGTCGGCGCCGGGCGCTTCCGCCAGGATCTCTACT
ACCGCCTCAACGTCATCGAATTGCGCGTTCCGCCCCTGCGCGAACGCCGCGAGGACATCCCGCTGCTGGCCGAGCGCATC
CTCAAACGCCTGGCCGGCGATACCGGCTTGCCAGCCGCCCGCCTGACCGGCGATGCCCAGGAAAAGCTGAAGAACTATCG
CTTCCCCGGCAACGTGCGTGAACTGGAGAACATGCTGGAGCGCGCCTACACGCTGTGCGAGAACGACCAGATCCAGCCCC
ACGACCTGCGCCTGGCCGACGCGCCGGGCGCCAGCCAGGACGGCGCGGCGAGCCTGAGCGAGATAGACAATCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCTCTCGAGGAGACCCGCTGGAACCGCACTGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGTTCGATGCGTTATCGCCTGAAGAAACTCGGCATAGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

98.652

100

0.987
  pilR Acinetobacter baumannii strain A118

51.416

100

0.53
  luxO Vibrio cholerae strain A1552

38.063

99.775

0.38

Multiple sequence alignment