Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   A6J87_RS08220 Genome accession   NZ_CP020451
Coordinates   1601029..1602903 (+) Length   624 a.a.
NCBI ID   WP_037601769.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1596029..1607903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS08205 (A6J87_08175) fmt 1598001..1598936 (+) 936 WP_014634814.1 methionyl-tRNA formyltransferase -
  A6J87_RS08210 (A6J87_08180) rsmB 1598926..1600248 (+) 1323 WP_080612074.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A6J87_RS08215 (A6J87_08185) - 1600292..1601029 (+) 738 WP_070839660.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  A6J87_RS08220 (A6J87_08190) stkP/pknB 1601029..1602903 (+) 1875 WP_037601769.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A6J87_RS08225 (A6J87_08195) - 1603048..1603806 (+) 759 WP_073950478.1 potassium channel family protein -
  A6J87_RS08230 (A6J87_08200) liaF 1603969..1604667 (+) 699 WP_037603001.1 cell wall-active antibiotics response protein LiaF -
  A6J87_RS08235 (A6J87_08205) - 1604664..1605674 (+) 1011 WP_002891418.1 sensor histidine kinase -
  A6J87_RS08240 (A6J87_08210) - 1605664..1606308 (+) 645 WP_002891417.1 response regulator transcription factor -
  A6J87_RS08255 (A6J87_08225) rimM 1607003..1607521 (+) 519 WP_060971504.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67954.70 Da        Isoelectric Point: 6.7045

>NTDB_id=223276 A6J87_RS08220 WP_037601769.1 1601029..1602903(+) (stkP/pknB) [Streptococcus salivarius strain FDAARGOS_259]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAIQTLNRKNISSSSIEYHDYNTGAKLDKDKVPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSNLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=223276 A6J87_RS08220 WP_037601769.1 1601029..1602903(+) (stkP/pknB) [Streptococcus salivarius strain FDAARGOS_259]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAAAAGTGGCTATTAAGGTACTTCGTACCAATTACCAAACTGATCAGGTGG
CTGTGGCCCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTCCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCGCAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACAAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAAAGTGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GCGATAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAACCACTACCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCTTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTACAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCTAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCGAAGGTTGATCCAGTTCCATCAGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAACCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAGAACTTCTTCTCAACCTTACTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCTTATTTAGTCTTTACCAATCCTGATAATGTCCAAGTACCTA
ATGTGGTCGGTCAGGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTG
GAAGATGACTCTGTCGATACGGGTAAGGTCATAAAGACCGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGATTCAAACCTTGAATCGTAAGAATATCT
CAAGTAGTAGCATCGAGTACCACGACTATAATACTGGTGCCAAATTAGATAAGGATAAGGTTCCTAGCAGTACGGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAA
CCTTCAGTCAAGCTCAAGTAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGATAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAACTACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(370-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.718

100

0.987
  pknB Streptococcus mutans UA159

66.974

86.859

0.582
  stkP Streptococcus pneumoniae D39

52.324

93.109

0.487
  stkP Streptococcus pneumoniae R6

52.324

93.109

0.487
  stkP Streptococcus pneumoniae Rx1

52.151

93.109

0.486
  stkP Streptococcus pneumoniae TIGR4

52.439

91.987

0.482

Multiple sequence alignment