Detailed information NTG0223274

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: A6J87_RS08150
• Genome accession: NZ_CP020451
• Coordinates: 1587112..1588197 (+)
• Length: 361 a.a.
• NCBI ID: WP_013990226.1
• Uniprot ID: A0A1V0H8X8
• Organism: Streptococcus salivarius strain FDAARGOS_259
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1582112..1593197

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J87_RS08135 (A6J87_08105)	amiA	1582652..1584622 (+)	1971	WP_070579760.1	peptide ABC transporter substrate-binding protein	Regulator
A6J87_RS08140 (A6J87_08110)	amiC	1584683..1586176 (+)	1494	WP_060971834.1	ABC transporter permease	Regulator
A6J87_RS08145 (A6J87_08115)	amiD	1586176..1587102 (+)	927	WP_022496729.1	oligopeptide ABC transporter permease OppC	Regulator
A6J87_RS08150 (A6J87_08120)	amiE	1587112..1588197 (+)	1086	WP_013990226.1	ABC transporter ATP-binding protein	Regulator
A6J87_RS08155 (A6J87_08125)	amiF	1588190..1589119 (+)	930	WP_002884751.1	ATP-binding cassette domain-containing protein	Regulator
A6J87_RS08160 (A6J87_08130)	-	1589172..1589957 (-)	786	WP_070576856.1	ABC transporter permease	-
A6J87_RS08165 (A6J87_08135)	-	1589969..1590667 (-)	699	WP_002886849.1	ABC transporter ATP-binding protein	-
A6J87_RS08170 (A6J87_08140)	-	1590672..1591049 (-)	378	WP_021143815.1	GntR family transcriptional regulator	-
A6J87_RS08175 (A6J87_08145)	-	1591231..1592025 (+)	795	WP_021143816.1	HAD-IIB family hydrolase	-
A6J87_RS08180 (A6J87_08150)	-	1592018..1592836 (+)	819	WP_014634817.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 40007.70 Da
• Isoelectric Point: 4.6135

>NTDB_id=223274 A6J87_RS08150 WP_013990226.1 1587112..1588197(+) (amiE) [Streptococcus salivarius strain FDAARGOS_259]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGQDL
TKLKSHQDWAPIRGAKIATIFQDPMTSLDPIKTIGSQIVEVIVKHQGKSAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDKGELFSIPGTPPSLYTPVVGDAFALRSDYAMQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVEKPEVIQNLHEKIRTNMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=223274 A6J87_RS08150 WP_013990226.1 1587112..1588197(+) (amiE) [Streptococcus salivarius strain FDAARGOS_259]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
CATTCGAGGAGTTTCCCTTGATCTGGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGTAAATCAGTTT
TGACTAAGACTTTCACAGGGATGCTTGAAGAAAATGGTCGTGTAGCTAGCGGTTCTATTGATTATCGTGGCCAAGATTTG
ACCAAACTTAAGAGTCACCAAGATTGGGCACCTATTCGTGGAGCTAAGATCGCGACTATCTTCCAAGATCCTATGACCAG
TCTTGACCCAATTAAGACTATCGGTAGCCAAATTGTTGAAGTCATTGTCAAACACCAAGGAAAATCAGCTAAAGAAGCTA
AAAAAATGGCCATTGATTACATGGACAAGGTTGGTATTCCTGATGCTGAAAAACGTTTCAACGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTCATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAGCCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATCGACCTCTTGAAATCACTCAAAGAGGAGTACGGTTTCTCAGTGA
TTTTCATTACCCATGACCTTGGTGTGGTAGCAAGTATCGCTGATAAGGTTGCTGTTATGTATGCTGGTGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCACCCATACACTTGGAGCTTGCTTTCAAGCTTGCCACAGTTGGC
TGACGATAAGGGTGAGCTTTTCTCTATTCCAGGGACACCACCATCACTTTATACACCAGTTGTTGGAGATGCCTTTGCCT
TGCGTTCAGACTATGCCATGCAAATTGACTTCGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCACCAAAAGTTGAAAAACCTGAGGTTATCCAAAATCTACATGAAAAAATCCGTACTAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A1V0H8X8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	99.169	100	0.992
amiE	Streptococcus thermophilus LMG 18311	96.399	100	0.964
amiE	Streptococcus thermophilus LMD-9	96.399	100	0.964
oppD	Streptococcus mutans UA159	54.728	96.676	0.529