Detailed information NTG0223269

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: A6J87_RS07640
• Genome accession: NZ_CP020451
• Coordinates: 1483139..1485379 (+)
• Length: 746 a.a.
• NCBI ID: WP_080611853.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_259
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1478139..1490379

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J87_RS07615 (A6J87_07585)	-	1479439..1479708 (-)	270	WP_037602798.1	GIY-YIG nuclease family protein	-
A6J87_RS07620 (A6J87_07590)	-	1479712..1480476 (-)	765	WP_080611852.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
A6J87_RS07625 (A6J87_07595)	-	1480526..1481461 (-)	936	WP_176744110.1	polysaccharide deacetylase family protein	-
A6J87_RS07630 (A6J87_07600)	-	1481591..1482346 (+)	756	WP_002948862.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
A6J87_RS07635 (A6J87_07605)	comEA	1482454..1483149 (+)	696	WP_021143743.1	helix-hairpin-helix domain-containing protein	Machinery gene
A6J87_RS07640 (A6J87_07610)	comEC/celB	1483139..1485379 (+)	2241	WP_080611853.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A6J87_RS07645 (A6J87_07615)	-	1485465..1486727 (+)	1263	WP_060971749.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
A6J87_RS07650 (A6J87_07620)	-	1486793..1487338 (+)	546	WP_048673823.1	GNAT family N-acetyltransferase	-
A6J87_RS07655 (A6J87_07625)	spxR	1487331..1488611 (+)	1281	WP_070577035.1	CBS-HotDog domain-containing transcription factor SpxR	-
A6J87_RS07660 (A6J87_07630)	-	1488651..1489511 (+)	861	WP_070577033.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84288.93 Da
• Isoelectric Point: 9.6833

>NTDB_id=223269 A6J87_RS07640 WP_080611853.1 1483139..1485379(+) (comEC/celB) [Streptococcus salivarius strain FDAARGOS_259]
MWLKKAPINLFSLSLLIAALYFTIFVTNVYAIGAFVFLMVCFLKHHWKNKAALKLVGLVGSFFLVYFLFLHHRASVQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKITLTPATGQRNFQGFNYQSY
LASKGIYRIAQIERLDQVVPQKSLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIVLLPFSLCYGLMTGWTASVLRSLVQSLLAEFGIKKLDNMGITLLLLFLL
LPHFLLTVGGVLSCSYAFLLCLFDFEDLSSLKKSIYTSLVLSIGNLPFLTYYYGTFQPVSLILTAIFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMESFLTWIQSWIGQPLILGKPSLFQFGLMIAVLILLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTVVDVGQGDSIFLRSMKGDTILIDVGGKVTFGTKEKWQESSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEEVAKCFKIKEICVSQGALTKPSFVKRLRTIKCPVHTLKAGDKLPMMGSNLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETIERFKQRH
IKILRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=223269 A6J87_RS07640 WP_080611853.1 1483139..1485379(+) (comEC/celB) [Streptococcus salivarius strain FDAARGOS_259]
ATGTGGCTTAAAAAAGCGCCAATCAATCTTTTTTCCTTGTCTCTTTTAATAGCTGCCCTTTATTTTACGATTTTTGTCAC
TAATGTTTACGCTATTGGTGCTTTTGTCTTTCTTATGGTCTGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCACCACAGAGCTAGCGTACAAGATAAACAA
GCCCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCAGCTATCGGTAA
GGCAAAGGGACAAACCTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTCAAGACTACTAGTCAAA
CGCTAGTATTAAAAGGGAAAATTACGTTAACCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTAAAGGTATTTATCGAATCGCTCAGATTGAGCGCTTGGACCAAGTGGTACCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCTTTGGTTCATATCCAGACGCACTTTCCTAGTCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGATATTTGGATAAGGAGTTCGATGAGCAGAGCCAGCTTTACACAAGTTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGTCTCCTACGCTTAGGTCTTCCTAAAGA
TTATCTATTTATCGTCTTGCTGCCTTTTTCCTTATGTTATGGCCTAATGACAGGATGGACAGCTTCAGTCCTACGTTCCT
TGGTTCAAAGTTTGCTGGCTGAGTTTGGTATTAAAAAACTGGACAATATGGGAATAACCTTGCTTCTATTGTTTCTCTTG
TTACCTCATTTTCTCTTAACAGTGGGAGGTGTATTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAGGA
CTTGTCATCTTTAAAGAAATCAATCTATACGAGCTTGGTATTGAGTATTGGGAATTTGCCCTTTCTAACTTACTATTATG
GAACCTTTCAACCAGTTAGTTTAATTCTAACAGCGATTTTTTCCATAGTATTTGATAGCTTTCTCTTGCCTGTATTGACA
GTATTCTTTGCCCTCTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGTCCTTTTTGACTTG
GATACAATCCTGGATAGGTCAACCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGA
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGACTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTGTGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACGTTTGGAACTAAGGAAAAATGGCAAGAGTCTAGCCAGACGAGCAATG
CAGAGAAAACCTTGATTCCCTATCTACAGGCTAGAGGAGTGTCTCAAATTGATTATCTAGTCCTGACGCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGGCCAAGTGTTTTAAGATTAAGGAAATCTGTGTCAGTCAGGGGGCTTTGACTAA
GCCTAGCTTTGTTAAAAGACTTCGGACTATAAAATGCCCAGTTCACACTCTAAAGGCTGGCGACAAATTACCCATGATGG
GAAGCAATCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGCGGTAACAATGATTCGATAGTTCTTTACGGAAAGCTA
TTAGGAAGCAGTTTTCTGTTTACCGGTGATTTGGAAAAAGAAGGAGAGGAGGAACTGATGGCCAGCTATCCAACTTTAAG
GGCAAGCGTCCTCAAAGCTGGACACCACGGTTCAAAAGGTTCTTCGTCTGAAGCTTTTTTGGACCAGCTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACAATAGAACGTTTTAAGCAACGCCAC
ATTAAAATTTTACGAACAGATAAAGACGGAGCCATCCGTTTTAAGGGCTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-694)

• Domain of unknown function (DUF4131) (DUF4131) (30-171)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	47.867	100	0.481
comEC/celB	Streptococcus mitis NCTC 12261	47.797	100	0.48
comEC/celB	Streptococcus pneumoniae Rx1	46.4	100	0.466
comEC/celB	Streptococcus pneumoniae D39	46.4	100	0.466
comEC/celB	Streptococcus pneumoniae R6	46.4	100	0.466
comEC/celB	Streptococcus pneumoniae TIGR4	46.061	100	0.462
comEC	Lactococcus lactis subsp. cremoris KW2	43.767	98.928	0.433