Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   A6J87_RS07635 Genome accession   NZ_CP020451
Coordinates   1482454..1483149 (+) Length   231 a.a.
NCBI ID   WP_021143743.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1477454..1488149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS07610 (A6J87_07580) - 1477651..1479237 (+) 1587 WP_008535313.1 DEAD/DEAH box helicase -
  A6J87_RS07615 (A6J87_07585) - 1479439..1479708 (-) 270 WP_037602798.1 GIY-YIG nuclease family protein -
  A6J87_RS07620 (A6J87_07590) - 1479712..1480476 (-) 765 WP_080611852.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  A6J87_RS07625 (A6J87_07595) - 1480526..1481461 (-) 936 WP_176744110.1 polysaccharide deacetylase family protein -
  A6J87_RS07630 (A6J87_07600) - 1481591..1482346 (+) 756 WP_002948862.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  A6J87_RS07635 (A6J87_07605) comEA 1482454..1483149 (+) 696 WP_021143743.1 helix-hairpin-helix domain-containing protein Machinery gene
  A6J87_RS07640 (A6J87_07610) comEC/celB 1483139..1485379 (+) 2241 WP_080611853.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A6J87_RS07645 (A6J87_07615) - 1485465..1486727 (+) 1263 WP_060971749.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  A6J87_RS07650 (A6J87_07620) - 1486793..1487338 (+) 546 WP_048673823.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24504.46 Da        Isoelectric Point: 4.6690

>NTDB_id=223268 A6J87_RS07635 WP_021143743.1 1482454..1483149(+) (comEA) [Streptococcus salivarius strain FDAARGOS_259]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTTLSTSSSKEGSKSLTEVSSQSKTEESEKDK
SKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSVNLAASLSDEEVIYVATKDENLSVLGQSGTSQVSDKG
GQTNAKDGKINLNTATAEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESIYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=223268 A6J87_RS07635 WP_021143743.1 1482454..1483149(+) (comEA) [Streptococcus salivarius strain FDAARGOS_259]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTCTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAACATTGTCAA
CCTCCTCATCCAAAGAAGGGTCAAAATCACTTACTGAAGTGTCTTCTCAGTCAAAGACGGAAGAAAGTGAAAAGGATAAG
TCAAAAGTAACAGTGGATGTTAAGGGGGCTGTGGCCAATCCAGGTGTTTATACCTTAAAAGCAAGCGCTAGGGTGACTGA
CGCCATCAAAGCCGCTGGGGGAATGACCGAGGATGCGGATGCTAAGAGTGTTAATTTAGCCGCAAGCTTGTCAGACGAAG
AGGTTATCTATGTAGCAACTAAGGATGAAAACCTTTCTGTCCTTGGTCAATCAGGAACTAGTCAGGTGTCTGACAAAGGA
GGACAAACTAATGCTAAGGATGGGAAAATTAACTTAAATACAGCGACTGCAGAGGAATTGCAAACCATTTCTGGAATTGG
AGCTAAGCGAGCAGAGGATATCATCGCCTATCGCGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACCTGAAAAATGTTT
CAGGAATTGGTGATAAAACGTTAGATAAAATCAGAGAGTCCATCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(168-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

89.177

100

0.892
  comEA/celA/cilE Streptococcus mitis SK321

40.435

99.567

0.403
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

40.175

99.134

0.398
  comEA Latilactobacillus sakei subsp. sakei 23K

34.855

100

0.364

Multiple sequence alignment