Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   A6J87_RS05490 Genome accession   NZ_CP020451
Coordinates   1083593..1084693 (+) Length   366 a.a.
NCBI ID   WP_125871313.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1078593..1089693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS05480 (A6J87_05470) - 1082326..1082688 (+) 363 WP_080611679.1 DUF1033 family protein -
  A6J87_RS05485 (A6J87_05475) comGA/cglA/cilD 1082770..1083711 (+) 942 WP_080611681.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J87_RS05490 (A6J87_05480) comYB 1083593..1084693 (+) 1101 WP_125871313.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J87_RS10985 (A6J87_10795) - 1084690..1084758 (+) 69 Protein_1025 competence protein ComGC -
  A6J87_RS05500 (A6J87_05485) - 1084770..1086260 (-) 1491 WP_225791454.1 recombinase family protein -
  A6J87_RS05505 (A6J87_05490) - 1086357..1086962 (-) 606 WP_225791455.1 hypothetical protein -
  A6J87_RS05510 (A6J87_05495) - 1086956..1087333 (-) 378 WP_080611682.1 ImmA/IrrE family metallo-endopeptidase -
  A6J87_RS05515 (A6J87_05500) - 1087340..1087705 (-) 366 WP_080611684.1 helix-turn-helix domain-containing protein -
  A6J87_RS05520 (A6J87_05505) - 1087874..1088077 (+) 204 WP_080611685.1 helix-turn-helix transcriptional regulator -
  A6J87_RS05525 (A6J87_05510) - 1088138..1088881 (+) 744 WP_080611687.1 phage antirepressor KilAC domain-containing protein -
  A6J87_RS11140 - 1089091..1089231 (+) 141 WP_404968625.1 BOW99_gp33 family protein -
  A6J87_RS05530 (A6J87_05515) - 1089279..1089605 (+) 327 WP_080611688.1 transcriptional regulator -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41692.70 Da        Isoelectric Point: 10.0357

>NTDB_id=223251 A6J87_RS05490 WP_125871313.1 1083593..1084693(+) (comYB) [Streptococcus salivarius strain FDAARGOS_259]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGTDLEEALMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=223251 A6J87_RS05490 WP_125871313.1 1083593..1084693(+) (comYB) [Streptococcus salivarius strain FDAARGOS_259]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCAAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGCATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATTCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCTCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCCAAGCTCTTTCGTGAGCT
GGGGACTGATTTAGAAGAGGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTACTCACCCTTTTTTCACTAAGG
AACTATCCTTGATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCTATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

55.102

93.716

0.516
  comYB Streptococcus mutans UA159

55.102

93.716

0.516
  comYB Streptococcus gordonii str. Challis substr. CH1

51.02

93.716

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.144

94.809

0.475
  comGB/cglB Streptococcus mitis SK321

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae Rx1

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae D39

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae R6

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae TIGR4

49.408

92.35

0.456
  comGB Lactococcus lactis subsp. cremoris KW2

45.646

90.984

0.415

Multiple sequence alignment