Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   A6J87_RS03385 Genome accession   NZ_CP020451
Coordinates   687836..689932 (-) Length   698 a.a.
NCBI ID   WP_080611564.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 682836..694932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS03360 (A6J87_03345) - 684378..684689 (-) 312 WP_002886559.1 urease subunit beta -
  A6J87_RS03365 (A6J87_03350) - 684701..685003 (-) 303 WP_002886558.1 urease subunit gamma -
  A6J87_RS03370 (A6J87_03355) - 685028..685543 (-) 516 WP_002886548.1 AmiS/UreI family transporter -
  A6J87_RS03375 (A6J87_03360) - 685948..687342 (+) 1395 WP_225791446.1 DUF4153 domain-containing protein -
  A6J87_RS03380 (A6J87_03365) - 687393..687725 (-) 333 WP_002886546.1 DUF805 domain-containing protein -
  A6J87_RS03385 (A6J87_03370) comA 687836..689932 (-) 2097 WP_080611564.1 peptide cleavage/export ABC transporter Regulator
  A6J87_RS03390 (A6J87_03375) comR 690107..691006 (-) 900 WP_049545716.1 helix-turn-helix transcriptional regulator Regulator
  A6J87_RS03395 (A6J87_03380) - 691185..691835 (-) 651 WP_070575879.1 phosphatase PAP2 family protein -
  A6J87_RS03400 (A6J87_03385) - 691838..692395 (-) 558 WP_080611565.1 ECF transporter S component -
  A6J87_RS03405 (A6J87_03390) - 692706..693215 (-) 510 WP_002886541.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  A6J87_RS03410 (A6J87_03395) trkA 693493..694842 (+) 1350 WP_037598979.1 Trk system potassium transporter TrkA -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78395.38 Da        Isoelectric Point: 9.3567

>NTDB_id=223235 A6J87_RS03385 WP_080611564.1 687836..689932(-) (comA) [Streptococcus salivarius strain FDAARGOS_259]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQGNLSY
PFIVHVVKEGGLQHYYTVFGQIKGQLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGEAYTKYKEDVPGLLSFLPILF
RRRGLIAVIVLLSFLVTLVNIIGSYYLQAIIDRLIPQGAYNLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIVQNQSLFLMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYREIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAF
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSANFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=223235 A6J87_RS03385 WP_080611564.1 687836..689932(-) (comA) [Streptococcus salivarius strain FDAARGOS_259]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGAGAGTTGGCTCAGACTTCTCGTGAAGGTACTTCTGCGCTTGGTTTGGTGG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGGAAACCTATCTTAT
CCTTTTATTGTACATGTGGTTAAAGAAGGTGGGCTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGCAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAATTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAGCCTATACTAAATACAAAGAAGATGTACCTGGACTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAGGGGGTTGATTGCAGTTATTGTCTTATTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAAGCTATTATCGACCGCTTGATTCCTCAGGGGGCCTATAATCTTCTGACCATGATTTCGCTAGGCTTATGTATCTCTT
ATCTTGCTCAACAAGTTTTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGTAATTACCTGTCCATTGCTGTCATT
CTTCCTTATATCAAGCATGTCCTTTCCTTGCCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGAGATGCCAACACTATTATAGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTGTACAAAATCAGTCACTTTTTTTGATGACTCTCACGGTAGTTCCTCTTTATGTTTTAATCATT
CTGGCATTCTATAAGCTTTTTGAAAAAGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGGGTTGAGGAAAGACGTTATCGGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCCTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGGTTAAAGACAGGGGTTCAGTTAGTTTCT
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTTATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTCAATTATTTTACAACTCCTTTAATTAATATCATCAATCTCCAATCTAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTTTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACTCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGAAAAACGACCTTAGCTAAAATGTTGTCAGGTTATTATACGAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCCATTAGCCATGCGGAGTTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACGGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGCTTTCAGACCCAAGTATCTGAAGACGGTGGTCTATCAG
GTGGTCAAAAACAACGTTTGGCTATAGCGAGGGCTCTCTTGTCCAAACAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAACCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTACGTCAACATGTTAGTCGTGTAGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGCGCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter transmembrane region (ABC_membrane)

(167-436)

ABC transporter (ABC_tran)

(494-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.835

98.997

0.533
  comA Streptococcus mitis NCTC 12261

53.401

98.997

0.529
  comA Streptococcus pneumoniae D39

53.256

98.997

0.527
  comA Streptococcus pneumoniae R6

53.256

98.997

0.527
  comA Streptococcus pneumoniae Rx1

53.256

98.997

0.527
  comA Streptococcus gordonii str. Challis substr. CH1

52.73

99.713

0.526
  comA Streptococcus pneumoniae TIGR4

53.111

98.997

0.526
  comA/nlmT Streptococcus mutans UA159

50.435

98.854

0.499

Multiple sequence alignment