Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   A6J87_RS03245 Genome accession   NZ_CP020451
Coordinates   662053..662742 (-) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 657053..667742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS03225 (A6J87_03210) dnaI 657848..658750 (-) 903 WP_002883792.1 primosomal protein DnaI -
  A6J87_RS03230 (A6J87_03215) - 658754..659929 (-) 1176 WP_014633897.1 DnaD domain protein -
  A6J87_RS03235 (A6J87_03220) nrdR 659926..660405 (-) 480 WP_002883820.1 transcriptional regulator NrdR -
  A6J87_RS03240 (A6J87_03225) covS 660527..662056 (-) 1530 WP_014633896.1 HAMP domain-containing histidine kinase Regulator
  A6J87_RS03245 (A6J87_03230) covR 662053..662742 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  A6J87_RS03250 (A6J87_03235) - 662897..663433 (-) 537 WP_037600313.1 DUF177 domain-containing protein -
  A6J87_RS03255 (A6J87_03240) rsmG 663732..664445 (+) 714 WP_048673867.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  A6J87_RS03260 (A6J87_03245) - 664514..665878 (+) 1365 WP_080611560.1 TrkH family potassium uptake protein -
  A6J87_RS03265 (A6J87_03250) - 665918..666589 (+) 672 WP_070575911.1 TrkA family potassium uptake protein -
  A6J87_RS03270 (A6J87_03255) - 666677..667507 (-) 831 WP_080611561.1 energy-coupling factor transporter transmembrane protein EcfT -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=223234 A6J87_RS03245 WP_002883757.1 662053..662742(-) (covR) [Streptococcus salivarius strain FDAARGOS_259]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=223234 A6J87_RS03245 WP_002883757.1 662053..662742(-) (covR) [Streptococcus salivarius strain FDAARGOS_259]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCCAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment