Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   A6J87_RS03240 Genome accession   NZ_CP020451
Coordinates   660527..662056 (-) Length   509 a.a.
NCBI ID   WP_014633896.1    Uniprot ID   A0AB33ZGE8
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 655527..667056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS03215 (A6J87_03200) - 655740..656369 (-) 630 WP_070575915.1 ribonuclease P -
  A6J87_RS03220 (A6J87_03205) der 656433..657743 (-) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  A6J87_RS03225 (A6J87_03210) dnaI 657848..658750 (-) 903 WP_002883792.1 primosomal protein DnaI -
  A6J87_RS03230 (A6J87_03215) - 658754..659929 (-) 1176 WP_014633897.1 DnaD domain protein -
  A6J87_RS03235 (A6J87_03220) nrdR 659926..660405 (-) 480 WP_002883820.1 transcriptional regulator NrdR -
  A6J87_RS03240 (A6J87_03225) covS 660527..662056 (-) 1530 WP_014633896.1 HAMP domain-containing histidine kinase Regulator
  A6J87_RS03245 (A6J87_03230) covR 662053..662742 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  A6J87_RS03250 (A6J87_03235) - 662897..663433 (-) 537 WP_037600313.1 DUF177 domain-containing protein -
  A6J87_RS03255 (A6J87_03240) rsmG 663732..664445 (+) 714 WP_048673867.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  A6J87_RS03260 (A6J87_03245) - 664514..665878 (+) 1365 WP_080611560.1 TrkH family potassium uptake protein -
  A6J87_RS03265 (A6J87_03250) - 665918..666589 (+) 672 WP_070575911.1 TrkA family potassium uptake protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58085.46 Da        Isoelectric Point: 5.1853

>NTDB_id=223233 A6J87_RS03240 WP_014633896.1 660527..662056(-) (covS) [Streptococcus salivarius strain FDAARGOS_259]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVIFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=223233 A6J87_RS03240 WP_014633896.1 660527..662056(-) (covS) [Streptococcus salivarius strain FDAARGOS_259]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTATTTTCTCAGCCAATACACTACTTTTACAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATAGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCTGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGTGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGACTCGCCTCCAGGTATGTCCGAGGTAAACAAATTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGCTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATCTTCCATGATTTGGAATTCTA
TTATGCTCTGAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCGACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGACATGTTGGATTCTATCCGTGTCAAAGGGTCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTCGAGAGTTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTGCAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACAACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATTCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.804

100

0.998

Multiple sequence alignment