Detailed information NTG0223200

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: A6J85_RS06600
• Genome accession: NZ_CP020450
• Coordinates: 1318453..1320693 (+)
• Length: 746 a.a.
• NCBI ID: WP_082307454.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS_257
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1313453..1325693

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J85_RS06580 (A6J85_06500)	-	1313902..1316271 (-)	2370	WP_048777519.1	cation-translocating P-type ATPase	-
A6J85_RS06585 (A6J85_06505)	-	1316401..1317141 (+)	741	WP_041789898.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
A6J85_RS06590 (A6J85_06510)	-	1317180..1317707 (+)	528	WP_082307452.1	HXXEE domain-containing protein	-
A6J85_RS06595 (A6J85_06515)	comEA/celA/cilE	1317804..1318469 (+)	666	WP_082307453.1	helix-hairpin-helix domain-containing protein	Machinery gene
A6J85_RS06600 (A6J85_06520)	comEC/celB	1318453..1320693 (+)	2241	WP_082307454.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A6J85_RS06605 (A6J85_06525)	holA	1320784..1321821 (+)	1038	WP_096755043.1	DNA polymerase III subunit delta	-
A6J85_RS06610 (A6J85_06530)	-	1321894..1322499 (+)	606	WP_045773124.1	superoxide dismutase	-
A6J85_RS06615 (A6J85_06535)	-	1322611..1323684 (+)	1074	WP_096755044.1	serine hydrolase	-
A6J85_RS06620 (A6J85_06540)	-	1323890..1324678 (+)	789	WP_096755045.1	YhfC family intramembrane metalloprotease	-
A6J85_RS06625 (A6J85_06545)	-	1324656..1324937 (+)	282	WP_012130660.1	autorepressor SdpR family transcription factor	-
A6J85_RS06630 (A6J85_06550)	-	1324924..1325421 (+)	498	WP_082307456.1	DUF1648 domain-containing protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85608.52 Da
• Isoelectric Point: 9.8830

>NTDB_id=223200 A6J85_RS06600 WP_082307454.1 1318453..1320693(+) (comEC/celB) [Streptococcus gordonii strain FDAARGOS_257]
MSQWIKKLPLSPIYLCFLLVWLYFAIYSGEKLAYMGVFLLIARLIWHYPRKKWLPTVAILIAFFIFFYARRELAERTFQS
QPAPARQVLVLPDTIKVNGDSLSFRGRIGGRLYQLYYKLASPREKESFQKLADLVTLEIEAEFNLAEERRNFSGFDYQAY
LKSQGIYRTVKVSRIMSSRSSQSANPFDWLSVWRRKALVFIKSTFPSPMSHYMTGLLFGDLDIDFAEMNDLYSSLGIIHL
FALSGMQVGFFMDVFRKILLRIGLRMETVDWLQFPLSFVYAGLTGFSVSVVRSLVQKLLSQFGVRRLDNFAMTVMVLMFL
MPSFLLTTGGVLSCAYAFIITMLDFEDSSGFRKAVLESLSISLGILPILIYYFAEFQPWSILLTFLFSIVFDTFMLPLLS
LIFLISPLFAFTQVNIFFQWLEMVIRWVASLSTRPIILGQPNLPLLIILLLVLALLYDFRKQKKIRVGLSLLAILLFFLS
KHPLQNEITVVDIGQGDSIFLRDVRGRTIVIDTGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDRLDKLVLTHTDT
DHMGDMLELAKHFSIREIYVSKGSMTQADFVDKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLTQGDGGNDDSIVLYGEF
FRTKFLFTGDLEALGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHKETLDRFEKIR
TKIFRTDEQGAIRFKGWNSWQIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=223200 A6J85_RS06600 WP_082307454.1 1318453..1320693(+) (comEC/celB) [Streptococcus gordonii strain FDAARGOS_257]
ATGTCACAGTGGATTAAAAAACTTCCCCTTTCACCAATCTACTTGTGCTTTCTTTTGGTTTGGCTCTACTTCGCTATTTA
TAGTGGGGAAAAGCTCGCTTATATGGGAGTTTTTCTGCTTATAGCCCGACTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTGTAGCTATCCTAATTGCTTTTTTTATCTTTTTTTATGCTAGACGTGAGTTGGCGGAGCGAACCTTTCAGTCT
CAACCAGCTCCAGCAAGACAAGTCTTAGTTTTACCAGATACAATTAAAGTAAATGGAGATTCCCTGTCATTCCGTGGTAG
AATAGGTGGCAGACTCTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAGAATCATTTCAAAAACTAGCGGACT
TGGTCACTTTAGAGATTGAAGCAGAGTTTAATCTAGCAGAAGAACGGCGCAATTTCTCTGGCTTTGACTATCAGGCTTAT
TTAAAAAGTCAGGGAATCTATCGGACGGTTAAGGTCAGTAGGATTATGTCTAGTCGTTCTAGTCAGTCTGCTAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCCTTGGTTTTCATTAAGTCTACTTTTCCAAGCCCGATGAGTCACTACATGA
CAGGACTCTTGTTTGGTGATTTAGATATTGATTTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAAGTTGGTTTTTTTATGGATGTCTTTCGGAAAATTCTTCTACGCATAGGCTTAAGGATGGA
AACAGTAGATTGGTTGCAATTCCCTTTGTCCTTCGTGTATGCTGGTTTGACCGGATTTTCTGTGTCAGTAGTTAGAAGTT
TAGTGCAAAAGTTGTTGTCTCAATTTGGAGTGAGGCGCTTGGATAATTTTGCGATGACCGTGATGGTTTTGATGTTTCTT
ATGCCAAGTTTTCTCCTGACAACAGGTGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACTATGTTGGATTTTGAGGA
TTCTAGTGGTTTTCGTAAAGCCGTGCTAGAGAGTTTAAGTATCTCGTTAGGCATTTTACCGATTCTTATCTACTATTTTG
CAGAATTCCAACCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTCTTTGATACATTTATGTTGCCTCTCTTGAGT
CTAATTTTTCTCATTTCGCCTTTGTTTGCCTTCACTCAAGTTAACATCTTCTTCCAATGGCTGGAAATGGTGATTCGTTG
GGTAGCTAGTTTGTCAACAAGGCCGATAATTTTAGGACAGCCAAATCTGCCTTTGCTTATTATTCTCCTGCTGGTCTTAG
CCTTGCTCTATGACTTTAGAAAACAAAAAAAGATTAGGGTTGGCCTGAGTCTCTTAGCAATCTTACTATTTTTCCTAAGT
AAACATCCTTTACAAAATGAAATCACAGTGGTAGATATTGGGCAGGGAGACAGTATATTTCTGAGAGATGTCAGAGGTAG
GACTATCGTGATTGATACAGGAGGACGGGTGGAGATTGGAAAAAAAGAAGCTTGGCAAGAGCGCGTGAGAAAAAGTAATG
CGGAAACGACCTTGATCCCTTATCTAAAAAGCCGAGGAGTGGATCGATTGGATAAATTGGTCTTGACTCATACCGATACA
GACCATATGGGAGATATGTTGGAGTTAGCTAAGCACTTTTCTATCCGAGAAATTTATGTTTCCAAAGGAAGTATGACTCA
AGCTGATTTTGTAGACAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTGGTCGAGGTGGGAGATCGGCTTCCTATTTTTG
ATTCGGCTCTTGAAGTGCTCTACCCGCTTACTCAAGGAGATGGAGGTAATGATGATTCAATTGTCTTGTATGGTGAATTT
TTCCGAACCAAGTTTCTTTTCACAGGAGATTTAGAAGCTCTAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAACCGTTACCAGCATCCGCATAAGGAAACTTTAGATAGATTCGAAAAAATCCGG
ACTAAGATTTTTCGGACAGATGAGCAGGGAGCTATTCGATTTAAAGGCTGGAATTCTTGGCAGATAGAAACGGTTCGCTA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

• Competence protein (Competence) (216-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	57.314	100	0.578
comEC/celB	Streptococcus pneumoniae TIGR4	56.359	100	0.564
comEC/celB	Streptococcus mitis NCTC 12261	56.434	100	0.564
comEC/celB	Streptococcus pneumoniae Rx1	55.689	100	0.558
comEC/celB	Streptococcus pneumoniae D39	55.689	100	0.558
comEC/celB	Streptococcus pneumoniae R6	55.689	100	0.558
comEC	Lactococcus lactis subsp. cremoris KW2	49.597	99.732	0.495