Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   A6J85_RS05955 Genome accession   NZ_CP020450
Coordinates   1183520..1184248 (+) Length   242 a.a.
NCBI ID   WP_082307404.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1178520..1189248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS05940 (A6J85_05875) - 1178692..1180257 (-) 1566 WP_060553909.1 ABC transporter substrate-binding protein/permease -
  A6J85_RS05945 (A6J85_05880) - 1180470..1182461 (+) 1992 WP_260468548.1 DUF2207 domain-containing protein -
  A6J85_RS05950 (A6J85_05885) - 1182550..1183398 (+) 849 WP_082307403.1 undecaprenyl-diphosphate phosphatase -
  A6J85_RS05955 (A6J85_05890) mecA 1183520..1184248 (+) 729 WP_082307404.1 adaptor protein MecA Regulator
  A6J85_RS05960 (A6J85_05895) - 1184242..1185408 (+) 1167 WP_082307405.1 glycosyltransferase family 4 protein -
  A6J85_RS05965 (A6J85_05900) sufC 1185495..1186265 (+) 771 WP_008809634.1 Fe-S cluster assembly ATPase SufC -
  A6J85_RS05970 (A6J85_05905) sufD 1186307..1187569 (+) 1263 WP_020992753.1 Fe-S cluster assembly protein SufD -
  A6J85_RS05975 (A6J85_05910) - 1187609..1188841 (+) 1233 WP_008809632.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28326.99 Da        Isoelectric Point: 4.1819

>NTDB_id=223187 A6J85_RS05955 WP_082307404.1 1183520..1184248(+) (mecA) [Streptococcus gordonii strain FDAARGOS_257]
MEVKQISESTIKITIKLEDLEEHGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKV
DKNLNFEDLADLPDMDELSQMTPDEFLKTLEKNIFEKSRDDIDAVQMLEKAEEEDASEPEEGQEQDRYIYYILRFSDLKN
LIAFTKTIHYPVDTSELYKMDQHYYLTILVDIEGRPSRYPAWLLATMREHAEDTDTTRALLQEHGHLLIVTDAVQHLQKV
NC

Nucleotide


Download         Length: 729 bp        

>NTDB_id=223187 A6J85_RS05955 WP_082307404.1 1183520..1184248(+) (mecA) [Streptococcus gordonii strain FDAARGOS_257]
ATGGAAGTGAAGCAAATTAGTGAATCAACAATTAAGATCACAATTAAATTAGAAGATCTAGAAGAGCACGGCATGGAGAT
GGCAGATTTTCTGGTTCCTCAGGAAAAGACGGAGGAATTTTTCTATACCATTTTAGATGAACTCGAAATGCCAGAAAGCT
TTTTAGATAGTGGAATGCTGAGTTTTCGGGTGACTCCAAAACCAGACAAATTAGACGTTTTTGTCACAAAATCTAAAGTA
GATAAAAATTTGAATTTTGAAGATTTGGCTGACTTGCCTGATATGGACGAACTGTCTCAAATGACTCCGGATGAATTTCT
AAAGACGCTTGAAAAAAACATCTTTGAAAAAAGCCGTGATGATATAGATGCTGTTCAAATGCTGGAAAAAGCAGAAGAGG
AAGATGCATCTGAGCCAGAAGAAGGGCAAGAACAAGATCGCTATATTTATTATATCTTGCGTTTTTCTGACTTGAAAAAT
CTGATCGCTTTCACCAAGACTATCCACTATCCAGTTGATACATCAGAGCTATACAAGATGGATCAGCATTACTATTTGAC
TATTCTAGTAGATATTGAAGGTCGTCCGAGTCGTTATCCTGCTTGGCTTCTGGCAACAATGCGTGAACATGCTGAGGATA
CAGATACGACGAGAGCCCTTCTTCAAGAGCACGGTCACTTGTTGATTGTAACAGATGCTGTGCAACATCTTCAAAAGGTA
AACTGCTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.306

100

0.661
  mecA Streptococcus pneumoniae D39

65.306

100

0.661
  mecA Streptococcus pneumoniae R6

65.306

100

0.661
  mecA Streptococcus pneumoniae TIGR4

65.306

100

0.661
  mecA Streptococcus mutans UA159

51.029

100

0.512
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.488

Multiple sequence alignment