Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   A6J85_RS00780 Genome accession   NZ_CP020450
Coordinates   138251..140104 (-) Length   617 a.a.
NCBI ID   WP_045772973.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 133251..145104
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS00755 (A6J85_00750) - 133874..134260 (-) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -
  A6J85_RS00760 (A6J85_00755) - 134257..135660 (-) 1404 WP_082307131.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  A6J85_RS00765 (A6J85_00760) - 135748..136380 (-) 633 WP_082307132.1 response regulator transcription factor -
  A6J85_RS00770 (A6J85_00765) - 136382..137383 (-) 1002 WP_082307133.1 sensor histidine kinase -
  A6J85_RS00775 (A6J85_00770) liaF 137380..138078 (-) 699 WP_045506061.1 cell wall-active antibiotics response protein LiaF -
  A6J85_RS00780 (A6J85_00775) stkP 138251..140104 (-) 1854 WP_045772973.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A6J85_RS00785 (A6J85_00780) - 140101..140841 (-) 741 WP_082307774.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  A6J85_RS00790 (A6J85_00785) rsmB 140862..142175 (-) 1314 WP_082307134.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A6J85_RS00795 (A6J85_00790) fmt 142165..143100 (-) 936 WP_061596060.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 67105.10 Da        Isoelectric Point: 6.5896

>NTDB_id=223150 A6J85_RS00780 WP_045772973.1 138251..140104(-) (stkP) [Streptococcus gordonii strain FDAARGOS_257]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRVTDIG
EEDGQQYLAMEYVAGLDLKRYIKEHSPLSNEEAVRIMGQILLAMRLAHARGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENANVP
QSLENVIIKATAKKLTDRYQSVSDMYVDLSSCLSPERRNEKKLMFDDAVKADTKTLPKIPQVTPPVASRVNNDPATDVEQ
KVPQVAPPTKPKKKHHLRARYKVLLAAVFLVIAAFLALLYLTPSNKQVPDVTGKTVAEAREAIEKVNLKVGEEIEENSDE
VASGMIIRTDPVAGTQRKEGSTVNLVVSKGAKTLIMEDYTGQTTAQAVERLTDVLKVPKNNIKVEEVETNDAEEGTIFEQ
TPAAGATYDLTSNTKIVLKVAKAVSTIEMPNFGSLQYTYANARNYLISLGIPSSNIERVVDRSVVSSQSDLVTSQSPATG
PVNPKKVKVTLYVTEATTQSSSSSSSSNSNSSSSSKNTSSSSSSEDETSASSSTHGD

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=223150 A6J85_RS00780 WP_045772973.1 138251..140104(-) (stkP) [Streptococcus gordonii strain FDAARGOS_257]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCAAACAAATTGGCCGAGGCGGGATGGCAGATGTCTA
TCTTGCCAAGGATTTGATTTTAGATGGTGAAGAAGTGGCGGTTAAGGTTCTTAGAACCAATTACCAGACGGATCCTATCG
CTGTTGCACGTTTCCAACGAGAAGCGCGTGCCATGGCGGATTTGGACCATCCACATATCGTTCGTGTCACCGATATTGGT
GAAGAAGACGGCCAGCAATATTTGGCTATGGAATATGTAGCTGGCTTGGATCTCAAACGTTATATCAAGGAACACTCTCC
TTTGTCGAACGAAGAGGCCGTTCGAATTATGGGGCAAATTCTTTTAGCCATGCGTTTGGCACATGCTCGTGGGATTGTTC
ACCGAGATTTGAAACCGCAAAACGTTCTCCTGACACCTGATGGAAATGCTAAGGTAACGGACTTTGGGATTGCGGTTGCC
TTTGCAGAAACAAGTTTGACCCAAACAAATTCCATGCTTGGCAGTGTCCATTATTTGTCTCCTGAGCAGGCGCGTGGTTC
GAAAGCAACTTTCCAAAGCGATATTTATGCGATGGGGATCATCTTTTATGAGATGCTGACTGGTCATATTCCTTATGATG
GGGATAGTGCAGTGACGATCGCTCTACAACATTTCCAAAAACCATTGCCGTCCATTATTGCTGAAAACGCCAATGTTCCG
CAGTCTTTGGAAAATGTTATTATTAAGGCTACCGCTAAAAAGCTGACAGACCGGTATCAGAGTGTTTCGGATATGTATGT
AGATCTGTCTAGTTGTTTATCACCTGAAAGACGGAATGAAAAGAAACTGATGTTTGATGACGCGGTAAAAGCGGATACTA
AGACACTTCCAAAGATTCCGCAAGTTACACCTCCTGTAGCTTCTAGAGTAAATAATGATCCAGCTACAGATGTTGAACAG
AAAGTCCCTCAAGTTGCACCGCCAACAAAACCTAAGAAAAAGCATCATTTGAGAGCTAGATACAAGGTTTTGTTAGCTGC
AGTATTTCTGGTCATTGCTGCTTTTCTAGCTTTGCTCTATCTAACACCATCTAATAAGCAGGTTCCAGATGTTACTGGCA
AGACAGTTGCTGAAGCTAGAGAAGCGATTGAAAAAGTCAATTTAAAAGTTGGCGAAGAAATAGAAGAGAATAGTGATGAA
GTAGCTTCTGGAATGATTATTCGAACAGATCCAGTGGCAGGGACTCAGAGAAAGGAAGGCAGTACGGTTAATTTAGTTGT
TTCTAAGGGAGCTAAAACGCTGATCATGGAAGACTATACTGGTCAAACTACTGCCCAAGCCGTTGAAAGGCTCACGGATG
TTCTAAAAGTTCCAAAAAACAATATTAAAGTTGAAGAAGTTGAAACAAACGATGCAGAAGAAGGAACAATTTTTGAACAG
ACACCAGCTGCGGGAGCTACCTATGATCTCACTTCAAATACGAAGATTGTTTTAAAAGTAGCCAAAGCAGTATCAACGAT
TGAAATGCCAAACTTTGGTAGCCTTCAATATACTTATGCAAACGCTCGGAATTATCTGATTTCTCTAGGAATTCCATCTA
GTAACATTGAAAGAGTCGTGGATCGTTCAGTTGTGTCGAGTCAATCTGATTTGGTGACATCACAATCTCCAGCAACTGGA
CCAGTTAATCCTAAGAAGGTAAAAGTAACCTTATATGTAACTGAAGCAACTACTCAAAGTTCAAGTTCTAGCTCAAGTTC
GAATTCTAACTCCTCATCAAGTAGTAAGAATACGTCATCGTCAAGTTCTTCAGAGGATGAAACTTCAGCATCAAGTTCGA
CACATGGTGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(435-502)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(508-574)

Protein kinase domain (Pkinase)

(12-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

70.543

83.63

0.59
  stkP Streptococcus pneumoniae D39

70.349

83.63

0.588
  stkP Streptococcus pneumoniae R6

70.349

83.63

0.588
  stkP Streptococcus pneumoniae Rx1

70.155

83.63

0.587
  pknB Streptococcus mutans UA159

57.168

92.707

0.53
  stkP/pknB Streptococcus salivarius strain HSISS4

57.847

88.817

0.514

Multiple sequence alignment