Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SPR_RS09050 Genome accession   NC_003098
Coordinates   1774530..1775429 (-) Length   299 a.a.
NCBI ID   WP_000904866.1    Uniprot ID   Q8DND0
Organism   Streptococcus pneumoniae R6     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1769530..1780429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPR_RS09030 (spr1799) rsmA 1770284..1771156 (-) 873 WP_001216869.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  SPR_RS09035 (spr1800) - 1771287..1771595 (-) 309 WP_000333257.1 hypothetical protein -
  SPR_RS09040 (spr1801) - 1771588..1772229 (-) 642 WP_000565531.1 ABC transporter ATP-binding protein -
  SPR_RS09045 (spr1802) - 1772231..1774261 (-) 2031 WP_000825280.1 bacteriocin-associated integral membrane family protein -
  SPR_RS09050 (spr1803) comR 1774530..1775429 (-) 900 WP_000904866.1 helix-turn-helix domain-containing protein Regulator
  SPR_RS09055 (spr1804) rnmV 1775501..1776061 (-) 561 WP_000664448.1 ribonuclease M5 -
  SPR_RS09060 (spr1805) - 1776061..1776834 (-) 774 WP_000575607.1 TatD family hydrolase -
  SPR_RS09065 (spr1806) - 1777140..1777859 (-) 720 Protein_1776 DUF1542 domain-containing protein -
  SPR_RS09070 (spr1807) rpmH 1778068..1778202 (-) 135 WP_000831905.1 50S ribosomal protein L34 -
  SPR_RS09075 (spr1808) - 1778347..1779561 (-) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  SPR_RS09080 (spr1809) - 1779717..1780010 (-) 294 WP_000977365.1 hypothetical protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35191.98 Da        Isoelectric Point: 4.8875

>NTDB_id=22315 SPR_RS09050 WP_000904866.1 1774530..1775429(-) (comR) [Streptococcus pneumoniae R6]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKELTEEWQEDVKKYL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=22315 SPR_RS09050 WP_000904866.1 1774530..1775429(-) (comR) [Streptococcus pneumoniae R6]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGGAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(7-59)

ComR tetratricopeptide (ComR_TPR)

(70-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DND0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.755

98.328

0.371
  comR Streptococcus suis P1/7

37.457

97.324

0.365
  comR Streptococcus suis 05ZYH33

37.457

97.324

0.365

Multiple sequence alignment