Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   A6J72_RS05430 Genome accession   NZ_CP020433
Coordinates   1091686..1093011 (+) Length   441 a.a.
NCBI ID   WP_216641942.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1086686..1098011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS05400 (A6J72_05415) dnaA 1086982..1088325 (-) 1344 WP_009569743.1 chromosomal replication initiator protein DnaA -
  A6J72_RS05405 (A6J72_05420) spo0J 1088551..1089318 (-) 768 WP_009569741.1 ParB/RepB/Spo0J family partition protein Regulator
  A6J72_RS05410 (A6J72_05425) htrA 1089373..1090563 (-) 1191 WP_009569739.1 S1C family serine protease Regulator
  A6J72_RS05415 (A6J72_05430) rlmH 1090767..1091246 (+) 480 WP_082311948.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  A6J72_RS05425 (A6J72_05440) - 1091523..1091669 (+) 147 WP_003075491.1 bacteriocin -
  A6J72_RS05430 (A6J72_05445) comD/comD1 1091686..1093011 (+) 1326 WP_216641942.1 GHKL domain-containing protein Regulator
  A6J72_RS05435 (A6J72_05450) comE 1093011..1093760 (+) 750 WP_003075488.1 competence system response regulator transcription factor ComE Regulator
  A6J72_RS05450 (A6J72_05465) - 1094084..1096660 (-) 2577 WP_082311949.1 YfhO family protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51882.73 Da        Isoelectric Point: 8.7063

>NTDB_id=223003 A6J72_RS05430 WP_216641942.1 1091686..1093011(+) (comD/comD1) [Streptococcus intermedius strain FDAARGOS_233]
MVKIEFVYWVIFSIIEAISVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFVKVKKV
KKHSSLFLALFLSLAVSGSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKIDFKENIVQ
LNFYLLFIHLLLNISHWLSNMKNLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEQEQLQLQKYTDEIVNLY
NEIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIEL
TFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGV
GRGLGLSNIKEIINNYEGIILDTKIEDEYFIQAMRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=223003 A6J72_RS05430 WP_216641942.1 1091686..1093011(+) (comD/comD1) [Streptococcus intermedius strain FDAARGOS_233]
ATGGTGAAAATAGAATTTGTATATTGGGTTATATTCTCCATTATAGAAGCTATTTCTGTTGTATATTGTTATAAGAAGAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAA
TACATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATACTTTGTTAAAGTAAAAAAAGTT
AAAAAACATTCGTCTTTATTTTTAGCACTATTTTTATCTTTAGCTGTATCAGGTTCTGAAACCTTCTTTTCAGTTATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTT
TCATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGATAGATTTTAAAGAAAATATTGTACAA
TTAAATTTTTATCTATTATTTATTCATCTTTTATTAAATATATCGCATTGGCTTAGTAACATGAAAAATTTAAATAGTTT
TTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAATTTTGTTCTACTTACAATCTATTCGCGAAAAATATG
AAAAAGAAGAACAAATTAAGCAAAAAGAACAGGAACAACTGCAATTACAAAAATATACAGATGAAATTGTTAATCTGTAT
AATGAAATTCGAGGTTTTCGTCATGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAGGTGATATAAA
AGAAGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATT
TAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTGTTTAAGGCACGAGATTACAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTTAAACCTTTGCCAATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTCCTTTTAAA
TAATGCAATAGAGGGAGCGGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTAGTAGATCTGGATACAGAAACGATCT
TAGTTATTCAAAATTCACGTAAGAAAAGACCTCTAGATTTGGAAGAAATTTACCAAACTGATTTTTCAACAAAGGGTGTG
GGACGTGGTTTAGGTTTAAGTAATATTAAAGAAATTATTAATAACTATGAAGGAATTATTCTGGATACTAAAATCGAAGA
TGAATATTTTATACAAGCAATGAGAGTGAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.795

99.32

0.544
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.299

100

0.544
  comD Streptococcus mitis SK321

46.939

88.889

0.417
  comD Streptococcus mitis NCTC 12261

48.404

85.261

0.413
  comD/comD2 Streptococcus pneumoniae TIGR4

47.872

85.261

0.408
  comD/comD1 Streptococcus pneumoniae Rx1

47.34

85.261

0.404
  comD/comD1 Streptococcus pneumoniae D39

47.34

85.261

0.404
  comD/comD1 Streptococcus pneumoniae R6

47.34

85.261

0.404

Multiple sequence alignment