Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   A6J72_RS03370 Genome accession   NZ_CP020433
Coordinates   683239..683988 (-) Length   249 a.a.
NCBI ID   WP_082311779.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 678239..688988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS03350 (A6J72_03345) - 678664..679896 (-) 1233 WP_082311777.1 cysteine desulfurase -
  A6J72_RS03355 (A6J72_03350) sufD 679913..681175 (-) 1263 WP_082311778.1 Fe-S cluster assembly protein SufD -
  A6J72_RS03360 (A6J72_03355) sufC 681215..681985 (-) 771 WP_003073743.1 Fe-S cluster assembly ATPase SufC -
  A6J72_RS03365 (A6J72_03360) - 682076..683242 (-) 1167 WP_003073746.1 glycosyltransferase family 4 protein -
  A6J72_RS03370 (A6J72_03365) mecA 683239..683988 (-) 750 WP_082311779.1 adaptor protein MecA Regulator
  A6J72_RS03375 (A6J72_03370) - 684115..684957 (-) 843 WP_003073751.1 undecaprenyl-diphosphate phosphatase -
  A6J72_RS03380 (A6J72_03375) - 685024..686913 (-) 1890 WP_082311780.1 DUF2207 domain-containing protein -
  A6J72_RS03385 (A6J72_03380) - 687040..688605 (+) 1566 WP_105255919.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 28966.72 Da        Isoelectric Point: 4.1860

>NTDB_id=222992 A6J72_RS03370 WP_082311779.1 683239..683988(-) (mecA) [Streptococcus intermedius strain FDAARGOS_233]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDIEAVRSLETAEAENSRSTSDMEEQEEDNDELTQKYIYYI
LKFANLREVIVFAKTVDYTVNTSELYKMDSHYYLTILVDIEGHPKRYPAWLLASMREHAEDTAVTRAVLQEHGYLLLVND
AVSNLQKVK

Nucleotide


Download         Length: 750 bp        

>NTDB_id=222992 A6J72_RS03370 WP_082311779.1 683239..683988(-) (mecA) [Streptococcus intermedius strain FDAARGOS_233]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAAGATTTAGAAGAACGTGGAATGGAGAT
GGCAGATTTTCTCGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCAGAGAGTT
TTTTGGATAGCGGTATGCTTAGTTTTCGTGTAACTCCTAAACCAGACCGACTGGATGTTTTTGTAACCAAGTCTAAGATT
GATAAGAATCTGAACTTTGATGATTTAGCAGATTTACCAGATGTAGAAGAGCTGTCTCAAATGTCTCCAGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGCAAAGACGATATTGAAGCTGTTCGGTCTTTGGAAACGGCAGAAGCAG
AAAATAGTAGAAGCACTTCTGATATGGAAGAACAAGAGGAAGATAATGACGAGCTAACACAAAAATATATATATTACATT
TTGAAGTTTGCCAACCTAAGAGAAGTGATTGTTTTTGCTAAAACGGTAGATTATACCGTCAATACTTCAGAGTTATACAA
AATGGACAGTCACTATTATTTGACAATTTTGGTTGATATTGAAGGCCATCCTAAGCGATATCCGGCTTGGCTTCTTGCAT
CTATGCGTGAACATGCAGAAGATACAGCTGTGACAAGAGCTGTTTTGCAAGAGCATGGTTACTTATTGCTTGTCAACGAT
GCGGTTTCCAATCTTCAAAAGGTTAAATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.145

99.598

0.679
  mecA Streptococcus pneumoniae D39

68.145

99.598

0.679
  mecA Streptococcus pneumoniae R6

68.145

99.598

0.679
  mecA Streptococcus pneumoniae TIGR4

67.742

99.598

0.675
  mecA Streptococcus mutans UA159

51.613

99.598

0.514
  mecA Streptococcus thermophilus LMD-9

45.703

100

0.47
  mecA Streptococcus thermophilus LMG 18311

45.312

100

0.466

Multiple sequence alignment