Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   A6J31_RS10910 Genome accession   NZ_CP020431
Coordinates   2111624..2112313 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus sp. FDAARGOS_192     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2106624..2117313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS10885 (A6J31_10825) - 2106856..2107686 (+) 831 WP_021143559.1 energy-coupling factor transporter transmembrane component T family protein -
  A6J31_RS10890 (A6J31_10830) - 2107776..2108447 (-) 672 WP_048790682.1 potassium channel family protein -
  A6J31_RS10895 (A6J31_10835) - 2108487..2109851 (-) 1365 WP_080611186.1 TrkH family potassium uptake protein -
  A6J31_RS10900 (A6J31_10840) rsmG 2109920..2110633 (-) 714 WP_048790684.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  A6J31_RS10905 (A6J31_10845) - 2110932..2111468 (+) 537 WP_002883813.1 DUF177 domain-containing protein -
  A6J31_RS10910 (A6J31_10850) covR 2111624..2112313 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  A6J31_RS10915 (A6J31_10855) covS 2112310..2113839 (+) 1530 WP_002883784.1 HAMP domain-containing histidine kinase Regulator
  A6J31_RS10920 (A6J31_10860) nrdR 2113961..2114440 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  A6J31_RS10925 (A6J31_10865) - 2114437..2115612 (+) 1176 WP_048790686.1 DnaD domain protein -
  A6J31_RS10930 (A6J31_10870) dnaI 2115616..2116518 (+) 903 WP_002883792.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=222915 A6J31_RS10910 WP_002883757.1 2111624..2112313(+) (covR) [Streptococcus sp. FDAARGOS_192]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=222915 A6J31_RS10910 WP_002883757.1 2111624..2112313(+) (covR) [Streptococcus sp. FDAARGOS_192]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACGCGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAACTATTGGCACGTATCCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTTGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment