Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   A6J31_RS10915 Genome accession   NZ_CP020431
Coordinates   2112310..2113839 (+) Length   509 a.a.
NCBI ID   WP_002883784.1    Uniprot ID   A0A1V0GG48
Organism   Streptococcus sp. FDAARGOS_192     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2107310..2118839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS10890 (A6J31_10830) - 2107776..2108447 (-) 672 WP_048790682.1 potassium channel family protein -
  A6J31_RS10895 (A6J31_10835) - 2108487..2109851 (-) 1365 WP_080611186.1 TrkH family potassium uptake protein -
  A6J31_RS10900 (A6J31_10840) rsmG 2109920..2110633 (-) 714 WP_048790684.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  A6J31_RS10905 (A6J31_10845) - 2110932..2111468 (+) 537 WP_002883813.1 DUF177 domain-containing protein -
  A6J31_RS10910 (A6J31_10850) covR 2111624..2112313 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  A6J31_RS10915 (A6J31_10855) covS 2112310..2113839 (+) 1530 WP_002883784.1 HAMP domain-containing histidine kinase Regulator
  A6J31_RS10920 (A6J31_10860) nrdR 2113961..2114440 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  A6J31_RS10925 (A6J31_10865) - 2114437..2115612 (+) 1176 WP_048790686.1 DnaD domain protein -
  A6J31_RS10930 (A6J31_10870) dnaI 2115616..2116518 (+) 903 WP_002883792.1 primosomal protein DnaI -
  A6J31_RS10935 (A6J31_10875) der 2116623..2117933 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  A6J31_RS10940 (A6J31_10880) - 2117998..2118627 (+) 630 WP_048790688.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58071.44 Da        Isoelectric Point: 5.1853

>NTDB_id=222916 A6J31_RS10915 WP_002883784.1 2112310..2113839(+) (covS) [Streptococcus sp. FDAARGOS_192]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=222916 A6J31_RS10915 WP_002883784.1 2112310..2113839(+) (covS) [Streptococcus sp. FDAARGOS_192]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCAGCCAATACGCTACTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAGGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCACCTAAAAATATCTATGCATCGATCATTAATGGTGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAATACAGATTCGCCTCCAGGTATGTCCGAGGTAAACAAACTGAAGTCAGTTTCTTATAAAGGGAAGCGTGGTTTC
TTGCTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCGACTG
TAGTTGTCCTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAAATCCTTGAGGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATCGGTAACTTCCGTGTCTTGCATGAAGACTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAGATGTTGGTCCAAGTGCA
AGATAATGGTGAAGGAATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GG48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

100

100

1

Multiple sequence alignment