Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   A6J31_RS06325 Genome accession   NZ_CP020431
Coordinates   1223636..1225507 (-) Length   623 a.a.
NCBI ID   WP_080610731.1    Uniprot ID   -
Organism   Streptococcus sp. FDAARGOS_192     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1218636..1230507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS06290 (A6J31_06225) rimM 1219013..1219531 (-) 519 WP_070656576.1 ribosome maturation factor RimM -
  A6J31_RS06305 (A6J31_06240) - 1220226..1220870 (-) 645 WP_002884791.1 response regulator transcription factor -
  A6J31_RS06310 (A6J31_06245) - 1220860..1221870 (-) 1011 WP_045768527.1 sensor histidine kinase -
  A6J31_RS06315 (A6J31_06250) liaF 1221867..1222565 (-) 699 WP_013990238.1 cell wall-active antibiotics response protein LiaF -
  A6J31_RS06320 (A6J31_06255) - 1222729..1223487 (-) 759 WP_080610730.1 potassium channel family protein -
  A6J31_RS06325 (A6J31_06260) stkP/pknB 1223636..1225507 (-) 1872 WP_080610731.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A6J31_RS06330 (A6J31_06265) - 1225507..1226244 (-) 738 WP_037604753.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  A6J31_RS06335 (A6J31_06270) rsmB 1226288..1227610 (-) 1323 WP_080610732.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A6J31_RS06340 (A6J31_06275) fmt 1227600..1228535 (-) 936 WP_080610733.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67772.43 Da        Isoelectric Point: 6.5787

>NTDB_id=222875 A6J31_RS06325 WP_080610731.1 1223636..1225507(-) (stkP/pknB) [Streptococcus sp. FDAARGOS_192]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEVE
DDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGEI
LSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSSTEVL
YQDPQAGTSVDGSVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=222875 A6J31_RS06325 WP_080610731.1 1223636..1225507(-) (stkP/pknB) [Streptococcus sp. FDAARGOS_192]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTAGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTTACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGGTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTAACAGGTCATATTCCTTACGATG
GCGATAGTGCTGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TACCGAAGGTTGATCCAGTTCCATCAGCAAGCCTTGAGAAAAAGGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCGAGGAAGAAAACGACACCAGCTAAGAAGAAAAAGAAGAATTTCTTCTCAACCTTACTCAAGGTTTT
CCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTAATG
TGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTTAAGGAAGTGGAA
GATGACTCTGTCGATACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACCACACGAAAAGAGGGATCAAGCATTGA
TGTCTATGTTTCTTCTGGTAGTAAAGGTTTTGCGTTGAAAGACTACAAAGGTAAAAACTACAAAGATGCCATTGAGGACT
TAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAAATC
CTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGTGGCAACTCC
TAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCTCAA
GTAGTAGTATCGAGTATCATGACTATAATACTGGTGCCAAGTTAGACAAGGATAAGGTTCCTAGCAGTACAGAGGTCCTT
TATCAAGATCCACAAGCTGGTACAAGCGTTGATGGTTCAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAGTCT
ACAGTCAAGCTCAAGCAGTACGACACACTCGTCATCCACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAACCT
CGACAGAGGCTACTCACACAGAGCTACAGTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(369-431)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(440-504)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.558

100

0.987
  pknB Streptococcus mutans UA159

67.159

86.998

0.584
  stkP Streptococcus pneumoniae TIGR4

50.997

96.629

0.493
  stkP Streptococcus pneumoniae D39

50.831

96.629

0.491
  stkP Streptococcus pneumoniae R6

50.831

96.629

0.491
  stkP Streptococcus pneumoniae Rx1

50.664

96.629

0.49

Multiple sequence alignment