Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C2H95_RS02770 Genome accession   NZ_CP026037
Coordinates   551899..553101 (-) Length   400 a.a.
NCBI ID   WP_134991656.1    Uniprot ID   -
Organism   Bacillus subtilis strain PK5_17     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 546899..558101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H95_RS02745 (C2H95_02740) rocE 547135..548538 (-) 1404 WP_032730280.1 amino acid permease -
  C2H95_RS02750 (C2H95_02745) rocD 548761..549966 (-) 1206 WP_072175728.1 ornithine aminotransferase -
  C2H95_RS02755 (C2H95_02750) rocR 550207..551592 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  C2H95_RS02760 (C2H95_02755) - 551574..551726 (-) 153 Protein_553 ATP-binding protein -
  C2H95_RS02765 - 551751..551879 (-) 129 WP_125121027.1 hypothetical protein -
  C2H95_RS02770 (C2H95_02760) htrA 551899..553101 (-) 1203 WP_134991656.1 serine protease HtrC Regulator
  C2H95_RS02775 (C2H95_02765) vicX 553183..553977 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  C2H95_RS02780 (C2H95_02770) walI 553999..554841 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  C2H95_RS02785 (C2H95_02775) walH 554828..556195 (-) 1368 WP_032722849.1 WalRK two-component regulatory system regulator WalH -
  C2H95_RS02790 (C2H95_02780) walK 556185..558020 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42742.47 Da        Isoelectric Point: 5.3321

>NTDB_id=222602 C2H95_RS02770 WP_134991656.1 551899..553101(-) (htrA) [Bacillus subtilis strain PK5_17]
MVDYDREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=222602 C2H95_RS02770 WP_134991656.1 551899..553101(-) (htrA) [Bacillus subtilis strain PK5_17]
ATGGTGGATTACGATCGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTAAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCTGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(182-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.542

100

0.417
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

44.242

82.5

0.365
  htrA Streptococcus pneumoniae D39

44.242

82.5

0.365
  htrA Streptococcus pneumoniae Rx1

44.242

82.5

0.365
  htrA Streptococcus pneumoniae R6

44.242

82.5

0.365