Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6J38_RS08740 Genome accession   NZ_CP020411
Coordinates   1756864..1758084 (+) Length   406 a.a.
NCBI ID   WP_005694369.1    Uniprot ID   -
Organism   Haemophilus influenzae strain FDAARGOS_199     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1751864..1763084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J38_RS08720 (A6J38_08725) corC 1752825..1753724 (-) 900 WP_005694364.1 CNNM family magnesium/cobalt transport protein CorC -
  A6J38_RS08725 (A6J38_08730) ampD 1754357..1754911 (-) 555 WP_005694366.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  A6J38_RS08730 (A6J38_08735) pilA 1755027..1755476 (+) 450 WP_005694367.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  A6J38_RS08735 (A6J38_08740) pilB 1755473..1756867 (+) 1395 WP_005694368.1 GspE/PulE family protein Machinery gene
  A6J38_RS08740 (A6J38_08745) pilC 1756864..1758084 (+) 1221 WP_005694369.1 type II secretion system F family protein Machinery gene
  A6J38_RS08745 (A6J38_08750) pilD 1758081..1758773 (+) 693 WP_005694370.1 A24 family peptidase Machinery gene
  A6J38_RS08750 (A6J38_08755) rho 1758827..1760089 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  A6J38_RS08755 (A6J38_08760) metJ 1760336..1760653 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  A6J38_RS08760 (A6J38_08765) cueR 1760667..1761053 (-) 387 WP_005654127.1 Cu(I)-responsive transcriptional regulator -
  A6J38_RS08765 (A6J38_08770) - 1761130..1761336 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  A6J38_RS08770 (A6J38_08775) - 1761411..1761617 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  A6J38_RS08775 (A6J38_08780) - 1761691..1761897 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  A6J38_RS08780 (A6J38_08785) - 1761972..1762178 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  A6J38_RS08785 (A6J38_08790) - 1762253..1762459 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  A6J38_RS08790 (A6J38_08795) - 1762533..1762739 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46290.54 Da        Isoelectric Point: 9.8695

>NTDB_id=222416 A6J38_RS08740 WP_005694369.1 1756864..1758084(+) (pilC) [Haemophilus influenzae strain FDAARGOS_199]
MTKKLFYYQASNPLNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIVLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
YQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=222416 A6J38_RS08740 WP_005694369.1 1756864..1758084(+) (pilC) [Haemophilus influenzae strain FDAARGOS_199]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACCCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCCACGTTGCTACAATCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTGTACTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCGGAGTTACCAACAATAACCGCAATATTGCTCTCAATATCTAATTTCCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
TATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCTGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

100

100

1
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Glaesserella parasuis strain SC1401

38.155

98.768

0.377

Multiple sequence alignment