Detailed information NTG0220975

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: B4X03_RS09690
• Genome accession: NZ_CP020085
• Coordinates: 2033425..2034621 (+)
• Length: 398 a.a.
• NCBI ID: WP_005711777.1
• Uniprot ID: B8F826
• Organism: Glaesserella parasuis strain CL120103
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2028425..2039621

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B4X03_RS09665	gpt	2028687..2029166 (+)	480	WP_021114522.1	xanthine phosphoribosyltransferase	-
B4X03_RS09670	gmk	2029292..2029918 (+)	627	WP_021113158.1	guanylate kinase	-
B4X03_RS09675	radA	2029971..2031347 (-)	1377	WP_021114521.1	DNA repair protein RadA	-
B4X03_RS09680	pilA	2031535..2031999 (+)	465	WP_005711781.1	pilin	Machinery gene
B4X03_RS09685	pilB	2032047..2033432 (+)	1386	WP_010787006.1	GspE/PulE family protein	Machinery gene
B4X03_RS09690	pilC	2033425..2034621 (+)	1197	WP_005711777.1	type II secretion system F family protein	Machinery gene
B4X03_RS09695	-	2034618..2035286 (+)	669	WP_043896635.1	prepilin peptidase	-
B4X03_RS09700	dapE	2035370..2036503 (+)	1134	WP_021114519.1	succinyl-diaminopimelate desuccinylase	-
B4X03_RS09705	clpX	2036577..2037827 (-)	1251	WP_021114518.1	ATP-dependent protease ATP-binding subunit ClpX	-
B4X03_RS09710	clpP	2037834..2038415 (-)	582	WP_005711766.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
B4X03_RS09715	-	2038516..2038905 (+)	390	WP_010787002.1	SufE family protein	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45575.38 Da
• Isoelectric Point: 10.1129

>NTDB_id=220975 B4X03_RS09690 WP_005711777.1 2033425..2034621(+) (pilC) [Glaesserella parasuis strain CL120103]
MNNIYEFQWKGRNRFGQKQTGRQLAESREVLEKRLQQKGYSQLSISRHFALPTAPKKEEINQFMQQLALLIQAKIPLKQS
LVMLLETCQNRTFYRWQQETIRLIEAGFALSVAFKKQGKYINPQEIQLIKMAETSGNLGLILTNIAQRREKSEKLAKKIK
KILFYPVFILAISITLSILLLLFIVPQFAELYGSKGKSLPLITEILFSLSHFLQHSILTLIILCVLCFLLIHILNKKTDL
IKRLKFIILSHIPILKGIIQYSRIIFFCQNSSLMLASHIRLDTVLHSFLANKSDDILLQGSLATTLTYLKQGYRLADSLD
PKLFPTDMLQMIAIGEQSGKLSPMLQQISDGYQQRLDYQIDILSQLLEPMLMVLMGIIVGTILVGLYLPIFDMGAMIE

Nucleotide

• Length: 1197 bp

>NTDB_id=220975 B4X03_RS09690 WP_005711777.1 2033425..2034621(+) (pilC) [Glaesserella parasuis strain CL120103]
ATGAATAACATTTATGAATTTCAATGGAAAGGACGCAACCGCTTTGGGCAAAAGCAGACAGGGCGACAGCTTGCCGAAAG
CCGAGAAGTGCTAGAGAAACGGTTGCAACAAAAAGGATACAGCCAGTTAAGCATTAGCCGACATTTTGCCTTGCCGACTG
CACCAAAAAAGGAAGAAATTAATCAATTTATGCAACAGTTAGCCTTATTAATTCAAGCTAAAATCCCCCTAAAACAGAGT
TTAGTGATGTTGCTTGAAACCTGCCAAAATCGCACTTTTTACCGTTGGCAACAAGAAACAATCCGCTTGATTGAAGCCGG
CTTTGCGTTATCCGTTGCCTTTAAAAAACAGGGAAAATATATTAATCCACAAGAAATCCAATTAATTAAAATGGCAGAAA
CAAGCGGTAATTTAGGGCTAATTTTAACCAACATTGCACAACGCCGTGAAAAATCGGAAAAATTAGCCAAGAAAATTAAA
AAAATTCTCTTTTATCCCGTCTTTATTTTAGCTATTTCAATCACACTCTCTATTTTATTATTGCTTTTTATTGTGCCACA
ATTTGCAGAACTTTATGGTTCAAAAGGAAAATCACTCCCTCTAATTACCGAAATACTCTTTAGCCTATCCCATTTTCTAC
AACACTCTATTTTAACGCTAATTATTTTATGTGTATTATGTTTTCTATTAATTCATATTTTAAATAAAAAAACAGATCTT
ATTAAACGCCTAAAGTTTATTATATTAAGCCATATTCCTATTTTAAAAGGCATTATCCAGTATTCACGCATTATCTTTTT
TTGTCAAAATAGCAGTTTAATGCTGGCTTCACATATTCGTTTAGATACTGTACTTCATTCCTTTTTAGCCAATAAAAGTG
ATGATATTTTATTACAAGGTTCTCTAGCAACTACACTAACTTATTTAAAACAAGGCTATCGTTTAGCCGACAGTTTAGAT
CCAAAACTCTTTCCTACGGATATGTTACAGATGATTGCCATTGGCGAGCAGAGCGGAAAATTATCGCCAATGTTGCAACA
AATCAGCGACGGTTATCAACAGCGGTTAGATTATCAAATTGATATACTTTCCCAATTATTAGAGCCGATGTTAATGGTGT
TAATGGGAATTATTGTAGGAACTATTTTAGTCGGGTTATATTTGCCGATTTTTGATATGGGAGCAATGATAGAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (63-186)

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

3D structure

• AlphaFold DB: B8F826

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	100	100	1
pilC	Haemophilus influenzae 86-028NP	38.155	100	0.384
pilC	Haemophilus influenzae Rd KW20	38.155	100	0.384