Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   BV083_RS02685 Genome accession   NZ_CP020006
Coordinates   546491..547828 (-) Length   445 a.a.
NCBI ID   WP_105210537.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 48P106H1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 541491..552828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV083_RS02660 (BV083_545) - 543221..543493 (-) 273 WP_005630954.1 HU family DNA-binding protein -
  BV083_RS02665 (BV083_546) - 543633..544223 (-) 591 WP_005686892.1 YjaG family protein -
  BV083_RS02670 (BV083_547) nudC 544259..545053 (-) 795 WP_005686893.1 NAD(+) diphosphatase -
  BV083_RS02675 (BV083_548) nfuA 545120..545716 (-) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -
  BV083_RS02680 (BV083_549) - 545792..546478 (-) 687 WP_005686895.1 ComF family protein -
  BV083_RS02685 (BV083_550) comE 546491..547828 (-) 1338 WP_105210537.1 type IV pilus secretin PilQ family protein Machinery gene
  BV083_RS02690 (BV083_551) comD 547838..548251 (-) 414 WP_005686898.1 pilus assembly protein PilP Machinery gene
  BV083_RS02695 (BV083_552) comC 548248..548769 (-) 522 WP_005686899.1 competence protein ComC Machinery gene
  BV083_RS02700 (BV083_553) comB 548766..549272 (-) 507 WP_005649305.1 competence protein ComB Machinery gene
  BV083_RS02705 (BV083_554) comA 549273..550070 (-) 798 WP_005686900.1 pilus assembly protein PilM Machinery gene
  BV083_RS02710 (BV083_555) - 550169..552763 (+) 2595 WP_005686901.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49207.47 Da        Isoelectric Point: 7.8816

>NTDB_id=219759 BV083_RS02685 WP_105210537.1 546491..547828(-) (comE) [Haemophilus influenzae strain 48P106H1]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQHDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPDGSITFDERSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=219759 BV083_RS02685 WP_105210537.1 546491..547828(-) (comE) [Haemophilus influenzae strain 48P106H1]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTAGAGCAATTAGCTTTTCAACATGATG
TCAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGAGTTTATTATTTAAACGGCAGCCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCACACTTAGTGAGTCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCCGATGGGAGCATTACCTTTGATGAACGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTTGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.652

100

0.987
  comE Haemophilus influenzae Rd KW20

97.528

100

0.975
  comE Glaesserella parasuis strain SC1401

52

95.506

0.497
  pilQ Vibrio campbellii strain DS40M4

43.198

94.157

0.407
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.476

92.584

0.393
  pilQ Vibrio cholerae strain A1552

42.476

92.584

0.393

Multiple sequence alignment