Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   BV083_RS02000 Genome accession   NZ_CP020006
Coordinates   416932..418149 (-) Length   405 a.a.
NCBI ID   WP_005686722.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 48P106H1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 411932..423149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV083_RS01960 (BV083_404) - 412817..413023 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  BV083_RS01965 (BV083_405) - 413097..413303 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  BV083_RS01970 (BV083_406) - 413388..413594 (-) 207 WP_015701556.1 heavy-metal-associated domain-containing protein -
  BV083_RS01975 (BV083_407) - 413679..413885 (-) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  BV083_RS01980 (BV083_408) cueR 413962..414348 (+) 387 WP_005663006.1 Cu(I)-responsive transcriptional regulator -
  BV083_RS01985 (BV083_409) metJ 414362..414679 (-) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  BV083_RS01990 (BV083_410) rho 414927..416189 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  BV083_RS01995 (BV083_411) pilD 416243..416935 (-) 693 WP_005686720.1 prepilin peptidase Machinery gene
  BV083_RS02000 (BV083_412) pilC 416932..418149 (-) 1218 WP_005686722.1 type II secretion system F family protein Machinery gene
  BV083_RS02005 (BV083_413) pilB 418146..419543 (-) 1398 WP_005686724.1 GspE/PulE family protein Machinery gene
  BV083_RS02010 (BV083_414) pilA 419540..419989 (-) 450 WP_005686726.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  BV083_RS02015 (BV083_415) ampD 420104..420664 (+) 561 WP_005686728.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  BV083_RS02020 (BV083_416) corC 421285..422184 (+) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46122.32 Da        Isoelectric Point: 9.7232

>NTDB_id=219752 BV083_RS02000 WP_005686722.1 416932..418149(-) (pilC) [Haemophilus influenzae strain 48P106H1]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRELTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQKKNQLISVTPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=219752 BV083_RS02000 WP_005686722.1 416932..418149(-) (pilC) [Haemophilus influenzae strain 48P106H1]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCGCGAGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAAAAGAAAAATCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAGGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.975
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.25

98.765

0.378

Multiple sequence alignment